“49ers Talk” hosts Matt Maiocco and Jennifer Lee Chan discuss San Francisco’s rivalry with the Seahawks and provide the latest injury updates before Matt speaks with general manager John Lynch on the importance of the team's Week 18 game. Also, offensive lineman Colton McKivitz joins Matt to share why home field advantage is so important in the postseason.

With a number of limited or nonparticipants in the 49ers' first practice of the week, depth players once again will need to step up and fill their role. What's also familiar is San Francisco's opponent in the regular-season finale on Saturday at Levi's Stadium: Sam Darnold and the Seattle Seahawks. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how clutch San Francisco's depth has been this season, especially in prime-time games. Also, they detail the many playoff permutations that will swirl following Week 18's results, along with just how much defensive coordinator Robert Saleh trusts his players and if Deommodore Lenoir will get a chance to shadow one of the league's best receivers Saturday in Jaxon Smith-Njigba.

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss the electric atmosphere at Levi's Stadium on Sunday and how San Francisco has proven all season that this iteration of the team is built for prime-time games. Also, the duo discusses how good of a job coach Kyle Shanahan and 49ers GM John Lynch have done keeping the team's competitive window open, as well as how a unique roster and season is capturing the hearts of the 49ers Faithful.

“49ers Talk” host Matt Maiocco provides the latest injury updates before speaking with general manager John Lynch about San Francisco's Week 17 matchup vs. the Chicago Bears. Also, NBC Sports' Cris Collinsworth joins Matt to discuss how Kyle Shanahan has done one of the best coaching efforts he's ever seen.

“49ers Talk” hosts Matt Maiocco and Jennifer Lee Chan preview San Francisco's Week 17 matchup against the Chicago Bears and discuss this week’s Pro Bowl selections before JLC is joined by "Sunday Night Football in America" host and former NFL head coach Tony Dungy to break down key matchups in 49ers-Bears and reflect on the Niners' improbable run to the playoffs this season.

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down the statement San Francisco made against the Colts in prime-time. Also, as the league results aligned in Week 16 in the 49ers' favor, Matt and Jennifer discuss how difficult the final two regular season games against the NFC's top two teams will be. The 49ers will attempt to rally behind their high-octane offense and ride the momentum to the No.1 seed.

“49ers Talk” host Matt Maiocco provides the latest injury updates before speaking with coach Kyle Shanahan about San Francisco's Week 16 matchup vs. the Indianapolis Colts. Also, Greg Papa joins Matt to discuss how the Los Angeles Rams’ Week 16 loss to the Seattle Seahawks opens the door for the 49ers to capture the NFC West and the NFC's No.1 playoff seed.

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down the Seattle Seahawks' shocking overtime victory against the Los Angeles Rams and how it affects the NFC playoff picture. Did the Rams have an early blueprint to stop the Seahawks they let slip away? And which area must the 49ers improve the most if they expect to contend for a now wide-open No. 1 seed? Matt and Jennifer also discuss the 49ers' looming matchup vs. Philip Rivers and the Indianapolis Colts on "Monday Night Football," and how close Rivers was to actually suiting up for San Francisco back in 2022.

It wasn't a picture-perfect performance Sunday vs. the Titans, but the 49ers returned from their bye week energized and executed when they needed to on their way to 37-24 victory at Levi's Stadium. Offensively, they looked sharp and scored on their first five possessions. Quarterback Brock Purdy threw for three touchdowns and zero interceptions as Ricky Pearsall finally broke through with a team-high 96 receiving yards and Jauan Jennings added two touchdowns. San Francisco's defense was tested, however, and will need to promptly turn things around with three regular-season games left and a ton on the line. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how San Francisco's offense is jelling at the right time, and how Purdy's confidence is contagious to the whole position group. They also detail how the 49ers' defense will need to step up amid a heated playoff race within their conference and, most importantly, their own division. San Francisco's postseason future is right in front of them, and they will play a large role in how it plays out down the stretch.

Kyle Shanahan joins "49ers Talk" co-host Matt Maiocco to discuss the challenges and benefits a late bye week presents San Francisco down the final stretch of the season. Matt asks Kyle how QB Brock Purdy can finish the season strong, evaluates wideout Ricky Pearsall's usage, and how the idea of meaningful December football can motivate his team. Greg Papa also joins Matt on this episode to break down how a young Tennessee Titans team with little to lose can present a dangerous obstacle for the 49ers. Papa points out where the 49ers need to fortify their resources on defense and if this is the game Pearsall can return to his early-season production

Hall of Fame linebacker Patrick Willis, now an Alumni Ambassador for San Francisco after spending his entire career in the Bay, joins "49ers Talk" co-host Matt Maiocco to discuss the impact Super Bowl LX can have on the region and how its immersive, family-friendly festivities can be enjoyed by all who attend -- whether they have a ticket or not. Patrick and Matt also tackle the 49ers' surprising run this season and how overcoming adversity has been a hallmark of their success. Willis expands on what San Francisco needs to focus on in its final four games, as well as how his relationship with the organization affords him the opportunity to connect with upcoming great 49ers players. Jennifer Lee Chan also joins Matt to paint the NFC playoff picture, review roster changes and injury updates, plus detail San Francisco's final stretch.

The 49ers enjoyed a bump in their playoff position without lifting a finger in their bye week, the last of the NFL season. The other teams battled it out in a blockbuster of matchups with gargantuan postseason implications across the board in both NFL conferences. In the NFC, the Green Bay Packers leapfrogged the Chicago Bears to take the No. 2 overall seed while dropping their division rivals to the seventh and final wild-card position, a precipitous fall for an opponent in one afternoon of work. The 49ers will play those Bears in a Sunday night clash in Week 17, which surely will intrigue. But, first come the Tennessee Titans in a matinee next Sunday, a potent opponent with nothing to lose. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan look ahead to San Francisco's final four games, a stretch that will test it in all phases and could define the rest of the team's entire season.

President of Football Operations/General Manager John Lynch joins '49ers Talk,' co-host Matt Maiocco for an update on the organization before San Francisco starts its final stretch of the 2025 NFL season. Lynch detailed the pride he has for the 49ers enduring tremendous adversity to place themselves squarely in the NFC playoff race before offering his expectations for the rest of the season. Jennifer Lee Chan also joins Maiocco to break down the 49ers' chances of making a deep playoff run as San Francisco begins to hit its stride.

Its Week 14 in the NFL, and the 49ers finally have reached their bye. As San Francisco players rest and recuperate, "49ers Talk" co-hosts Matt Maiocco and Jennifer Lee Chan take a pulse on the 49ers' season with just four regular-season games left. Jennifer, Matt, and later Greg Papa, discuss if Kyle Shanahan's current coaching staff is his best yet, and if that makes him a strong candidate for his first NFL Coach of the Year award. They also detail the 49ers' latest injuries and roster additions, then discuss if Christian McCaffrey's public support of Roger Craig can convince the Pro Football Hall of Fame committee to induct the legendary 49ers running back.

The 49ers, on Sunday, notched their first three-game winning streak since the opening three weeks of the season and won in Cleveland for the first time since Nov. 1984. The 49ers' latest win was exhibition in execution from the kickoff as they played complimentary football in all three phases. Brock Purdy played errorless football with excellent decision-making, while extending plays when needed. The special teams group bolstered the 49ers' field-position on returns and made timely kicks when needed, while the defense has been humming the last few weeks, creating turnovers and finally adding an element of pressure from the D-line that spurred San Francisco to victory. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco's decisive 26-8 road win over the Cleveland Browns at Huntington Bank Field. From Brock Purdy's bounce-back performance following a mistake-filled game, to special teams and defensive units flourishing, to a coach committed to his preparation and scheme in what might be his best coaching season for the Faithful, Matt and Jennifer detail a team finding health and success in time for a much-needed break during their Week 14 bye week.

San Francisco's president of football operations John Lynch sat down with “49ers Talk” host Matt Maiocco this week to preview their Week 13 matchup vs. the Cleveland Browns and provide organizational news and updates. Maiocco and Lynch also discuss how Brock Purdy can bounce back in Week 13 following a poor display against the Carolina Panthers, Brandon Aiyuk's current relationship with the organization in light of his contract situation, and how San Francisco's special teams group has turned from a liability last season into a weapon this year. Finally, Maiocco provides injury updates that will affect the 49ers' defense Sunday and names the five key San Francisco players to watch in Week 13.

The 49ers are entrenched in the final NFC playoff spot as they prepare to face the Cleveland Browns. However, with low temperatures, high-winds, and possible perception forecast for Sunday's matchup, holding onto that precious wild card spot might be more complicated. Having lost their previous contest in Cleveland under similar conditions in 2023, San Francisco will be tasked with executing their offense more efficiently this time while mitigating current NFL sack leader Myles Garrett. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss Brock Purdy's regression last week against the Panthers and how he and the 49ers' offense can minimize mistakes against familiar obstacles in inclement weather and a formidable pass-rush. Also, Matt and Jennifer provide injury updates, surprising takes on a San Francisco offensive line playing well under-the-radar and where the 49ers might look in the draft. They also praise the evolution of Christian McCaffrey's game during an incredible individual season.

The 49ers entered Monday night knowing the needed a win to distance themselves from another NFC playoff contender in the Carolina Panthers. Despite three uncharacteristic interceptions from quarterback Brock Purdy, the 49ers' defense stepped up to secure a 20-9 victory as safety Ji'Ayir Brown's two interceptions helped San Francisco hold Carolina to single digits. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss Purdy's dip in form and whether he's physically 100 percent, linebacker Curtis Robinson's long-awaited first NFL start and Brown's career night. Finally, wide receiver Brandon Aiyuk's curious contract situation is highlighted: With five regular-season games remaining, will he return? And what are the motivating factors for both parties if he does?

“49ers Talk” host Matt Maiocco discusses the latest news on Brandon Aiyuk before speaking with coach Kyle Shanahan about San Francisco's Week 12 matchup vs. the Carolina Panthers on Monday night. Also, Greg Papa joins Matt to discuss Brock Purdy’s performance against the Arizona Cardinals in Week 11 and reflect on the trade that brought Christian McCaffrey to the 49ers.

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan reflect on the blockbuster trade that brought Christian McCaffrey to San Francisco ahead of Monday night's matchup against his former team. Additionally, Matt and Jennifer discuss how a healthy 49ers offense will improve their run game. Matt then sits down with defensive back Deommodore Lenoir to discuss his growth as a leader and team captain of the 49ers’ defense.