What happens when a healthy 8-year-old boy begins tripping, falling, and experiencing double vision? For Katie and Nick Macri, and grandparents Tim and Maggie McNiff, these early warning signs led to every family’s worst nightmare: a diagnosis of diffuse intrinsic pontine glioma (DIPG), a rare and aggressive tumor located in the brainstem.In this emotional episode of Believe in Progress, brought to you by the AACR Foundation, we sit down with the family of John Paul (JP) to discuss their journey through diagnosis and treatment.Part One introduces us to JP and his family. Katie and Nick recount the heartbreaking timeline from subtle symptoms to the harrowing moments of receiving the diagnosis. They discuss the devastating nature of a tumor located in the pons region of the brainstem and the "state of unknowing" that follows such news. We also hear from JP’s grandparents, Tim and Maggie, on dropping everything to support their grandchildren, and how the family navigated difficult conversations with JP’s older brother, Luke.Part Two focuses on the incredible resilience that defines JP’s journey. The family discusses their decision to pursue a clinical trial involving CAR T-cell therapy at Seattle Children’s Hospital to preserve JP's quality of life. The conversation shifts to the power of community—from a neighborhood Nerf war to the James Madison University football team adopting JP as an honorary captain. Finally, Nick and Tim discuss their initiative to accelerate research through the "M3 database," an AI-driven project designed to speed up data sharing for pediatric brain cancer.This is a story about cancer science and a little boy who refuses to let a dire diagnosis define his spirit.Featured GuestsKatie and Nick Macri – John Paul’s parentsKatie and Nick share their raw and honest experience navigating pediatric cancer, balancing full-time work with cross-country travel for treatment, and relying on their deep faith to carry the burden of the unknown.Tim and Maggie McNiff – John Paul’s grandparentsTim and Maggie offer the perspective of the extended family "village." They discuss the role of grandparents in a crisis and their work to support logistical and scientific initiatives to help their grandson.Key Topics:Part One – The Diagnosis and The Family Unit• Early Warning Signs: Identifying subtle symptoms like redness in eyes, head tilting, and loss of balance• The Diagnosis: Understanding DIPG and the initial prognosis• Sibling Impact: How JP’s older brother Luke is processing the illness and the attention surrounding it• The Power of Vulnerability: Why Nick and Katie chose to be open on CaringBridge rather than keeping the diagnosis privatePart Two – Innovation, Community and The "Green Bracelet" Army• CAR T-Cell Therapy: Choosing an innovative clinical trial over traditional chemotherapy to maintain quality of life• The JMU Connection: How the James Madison University football team embraced JP, from the weight room to the coin toss• The M3 Database: Nick and Tim’s effort to use AI and data centralization to help researchers share MRI and genomic data faster• Community Support: How neighbors, colleagues, and strangers lift the family up dailyTake Action to Advance Cancer Science and Medicine:If this episode moved you, here’s how you can take action to support families like the Macris:• Donate to the AACR: Fuel lifesaving innovation at https://AACR.org/Give• Check out the inaugural AACR Pediatric Cancer Progress Report, which highlights the advances and challenges in the field, at https://PediatricCancerProgressReport.

What happens when an elite athlete, known for his focus and discipline, faces a life-changing diagnosis? In this episode of Believe in Progress, a podcast of the AACR Foundation, we sit down with Steve Dawson, a titan in the world of pickleball, to discuss his experiences with prostate cancer.Part One: We explore Steve’s initial diagnosis, which came as a shock following a routine physical with no prior symptoms. Steve discusses his decision-making process regarding surgery versus radiation and the "state of unknowing" that accompanies a cancer journey. He discusses how his athletic background prepared him to tackle treatment head-on and the importance of men overcoming the stigma of discussing their health.Part Two: We dive into the intersection of passion and recovery. Steve shares how a cancer recurrence became the catalyst for launching his own paddle company, Aura, and reflects on the unique, supportive nature of the pickleball community. He shares candid, humorous, and vulnerable stories, including winning a bronze medal at the US Open while recovering from surgery, and discusses his "expiration date" philosophy that makes every sunset better and every glass of wine taste a little sweeter.This conversation highlights the importance of early detection, the power of an active lifestyle, and the refusal to let a diagnosis define one’s limits.Featured GuestSteve Dawson - Professional Pickleball Player, Coach, and Entrepreneur A legend in the sport with 18 majors to his name, Steve Dawson is the owner of the Bobby Riggs Racket and Paddle Club and the founder of Aura. He uses his platform to advocate for prostate cancer awareness and emphasizes the critical need for PSA screenings.Key Topics:Part One – The Diagnosis & Mindset* The silent nature of prostate cancer: How a routine physical that found a spike in PSA levels led to Steve’s diagnosis.* Navigating treatment options: The choice between surgery and radiation.* The "state of unknowing": Managing the anxiety of diagnosis and recurrence.* Breaking the silence: Why Steve feels men should talk more openly about cancer and "Man Up to Cancer."* How physical fitness and an athlete’s mentality aided Steve’s recovery from surgery.Part Two – Community, Innovation & Resilience* The pickleball melting pot: How the sport builds a diverse, supportive network for patients.* Turning adversity into action: How a cancer recurrence motivated the founding of his company, Aura.* The bronze medal story: A humorous and gritty look at competing in the US Open immediately post-surgery.* Integrative approaches: Combining Western medicine with Eastern holistic practices (diet, herbs, and stretching).* Reframing the narrative: Viewing cancer survivorship as a tool to appreciate the vibrancy of life.Take Action in the Fight Against Cancer:If this episode moved you, here’s how you can take action to advance cancer research:* Get screened: If you are eligible, talk to your doctor about a PSA test. It could save your life.

What happens when a life in media, advocacy, and leadership converges on a mission to transform the way we support people with cancer? On this episode of Believe in Progress, the AACR Foundation’s podcast, we hear from Suzanne St...

What does it take to lead one of the world’s largest gatherings of cancer researchers and to deliver cancer care on the front lines of a war zone? In this powerful episode of Believe in Progress, brought to you by the AACR Foundation, we sit down wi...

What does it take to face cancer head-on, twice, and still find the strength to run toward progress? In this powerful episode of Believe in Progress, brought to you by the AACR Foundation, Rhett Austell shares his deeply personal journey through stage 4 appendix cancer, fatherhood, advocacy, and the fight for his life.Rhett’s story is one of resilience. From the sudden onset of cancer in his late 30s to undergoing major surgery, chemotherapy, and still lacing up to run the Broad Street Run in Philadelphia, he embodies what it means to keep going, no matter the odds. His passion for funding cancer research is fueled by both the personal loss of his father and by hope: through his father-in-law’s survival, thanks to a clinical trial.This special extended episode includes a heartfelt epilogue recorded after Rhett’s recent cancer recurrence, where he speaks openly about the realities of a second diagnosis, his continued treatment, and what drives him to keep fighting—not just for himself, his wife, and his four daughters, but for all cancer patients and their families. Key Topics: * The shocking discovery of stage 4 appendix cancer at age 38* The emotional rollercoaster of becoming a father again amid diagnosis* Lessons learned from his father’s and father-in-law’s cancer journeys* Running the Broad Street Run after major surgery and raising more than $9,000* Facing a cancer recurrence and embracing advocacy with renewed urgency* The importance of time, clinical trials, and fully funding cancer research* What it means to believe in progress, even in the face of setbacksEpisode Chapter Markers (Timestamps): 00:00 – Introduction to Believe in Progress00:53 – Rhett's Story Begins03:09 – A Surprise Diagnosis and a New Baby on the Way08:12 – Treatment, Surgery, and Finding Strength Through Family09:28 – Cancer in the Family: Stories of Loss and Survival14:48 – Why Cancer Research Matters Now More Than Ever16:55 – Running Again: From the Hospital to the Finish Line20:23 – Fundraising, Broad Street Run, and Victory21:49 – Epilogue: Facing Recurrence with Purpose27:34 – Rhett’s Second Round of Treatment32:29 – Continued Advocacy in the Face of Uncertainty36:04 – Looking Ahead: Hope, Family, and Next GoalsIf this episode moves you, here’s how you can take action to advance cancer research:* Donate to the AACR: Fuel lifesaving innovation at https://AACR.org/Give (https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Faacr.org%2FGive&data=05%7C02%7Crachel.taschenberger%40aacr.org%7Ca360e90c8d524aafa07808de1b4bd412%7C246e714fe4c240eba104f70e9c80d6dc%7C1%7C0%7C638978209678974087%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=MwEcEsigCidB3gWfzpBbAkNmNvP%2FABmnCTPYtNlxwcc%3D&reserved=0)* Share this episode: Send it to inspire others in your network* Subscribe to Believe in Progress: Listen on Apple Podcasts, Spotify, YouTube, or wherever you get your podcastsProduction Credits: Host: Mitch StollerGuest: Rhett AustellExecutive Producer: Anthony LopesExecutive Producer: Michael LearyDirector: Anthony LopesCreative Director / Director of Photography: Michael LearyWriter: Anthony LopesEditor: Michael LearyAssociate Producer: Heather Holland Believe in Progress is produced by CollegeCast LLC.

Your support matters. Help accelerate progress against cancer:* Donate to the AACR: Fuel lifesaving cancer research at https://AACR.org/Give (https://aacr.org/Give).* Share this episode: Amplify Patty’s and Vicki’s messages of early detection, advocacy, and hope.* Subscribe to Believe in Progress: Follow us on Apple Podcasts, Spotify, YouTube, or wherever you listen.What does it look like to face breast cancer with courage, clarity, and community?In this episode, we talk with Patty Guthrie and Vicki Courlang about the moments that changed everything in their lives and the choices that carried them forward. Patty describes retiring after 25 years of teaching, staying on top of her annual mammograms, and catching her cancer early—at Stage 1 in 2020—as well as navigating treatment during COVID-19. She credits her care team at Memorial Sloan Kettering, daily gratitude, and walking five to six days per week as pillars of her recovery.Vicki brings a clinician’s insight to a patient’s journey. A former oncology nurse, she recognized something was “off” long before her diagnosis with Paget’s disease of the breast. Paget’s is a rare condition that, for Vicki, didn’t appear on standard mammograms. She emphasizes listening to your body, seeking prompt evaluation for changes, and advocating for screening access at younger ages.Both guests underscore the lifesaving importance of early detection, the reality of vulnerable moments, and the power of family, friends, and compassionate care.Their message is clear: education, advocacy, and cancer research save lives, and hope grows from science and facing our challenges of cancer together.Episode Highlights:* Early Detection Saves Lives: Patty’s annual screening caught a small, hard-to-feel tumor, and Vicki’s Paget's symptoms appeared externally and did not show on standard mammograms. This is where self-awareness and follow-up mattered.* Treatment in a Pandemic: Chemotherapy and radiation during COVID-19 meant isolation at appointments. However, nurses, techs, and loved ones created a safety net.* Caregiver and Patient Dual Lens: Vicki’s oncology background helped her understand next steps; Patty learned fast and stayed positive through her cancer journey.* Support Systems: Spouses, children, and close friends (shoutouts included) made a big difference. They helped with rides to appointments, meals, calls, and presence.* Survivorship Milestones: From frequent follow-ups to annual imaging and bone-density checks, survivorship is a structured path, which includes daily movement and gratitude.* Mindset Shifts: Cancer doesn’t define who you are; it’s part of what you are. Boundaries, positivity, and purpose take center stage.* Practical Advice: Stay informed. Get your screenings. Seek second opinions. Choose a team and a care plan you feel confident in and move forward.How You Can Help:* Donate to the AACR: Support world-class cancer research at AACR.org/Give* Subscribe & Share: Help this episode reach patients, caregivers, and clinicians who need it* Leave a Review: Ratings and reviews help others discover the showProduction Credits:

Your support matters! Take action to propel progress in cancer science and medicine:* Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give (https://aacr.org/Give)* Share this episode: Help amplify Justin’s story and advance research for the benefit of caregivers, survivors, and all those impacted by cancer* Subscribe to Believe in Progress: Find us on Apple Podcasts, Spotify, YouTube, or wherever you listenEpisode Summary:How far would you go to protect the person you love most in the world?In this emotional and inspiring episode, Justin Wineburgh, President and CEO of Alkemy X, sits down with host Mitch Stoller to share the extraordinary story of his mother Iris: a single mom of three, a “force of nature,” and a woman whose love defined his world.Justin reflects on the moment everything changed: Iris’s ovarian cancer diagnosis on December 30, 1999. From that day forward, he became not just her son, but her advocate, her caregiver, and her anchor. Together, they navigated hospital rooms, treatment plans, and the emotional landmines of uncertainty, while holding tightly to moments of laughter, love, and connection.Faced with heartbreak after hearing about his mother's diagnosis, Justin found purpose: immersing himself in cancer research, standing fiercely by his mother’s side, and eventually becoming a father himself just weeks after her death in 2024. Today, he carries her legacy forward through storytelling, empathy, and relentless hope.Episode Highlights:* Meeting Iris: A single mom of three boys and a fierce, vibrant woman remembered as “a force of nature”* The Diagnosis: How a flip phone call from a young resident changed their lives forever* The Cancer Journey: Chemotherapy, second opinions, and choosing to get care close to home in Philadelphia* Caregiver Realities: Rage, love, exhaustion, and learning that “no one knows nothing”* Life After Loss: Navigating grief, becoming a father, and wearing Iris’s belt as a daily reminder of love* Why Research Matters: The drug that helped in her final year didn’t exist when she was first diagnosed* A Son’s Message: “If you can get one extra day with your loved one because of research, it’s worth everything”Production Credits:* Host: Mitch Stoller* Guest: Justin Wineburgh* Executive Producer: Anthony Lopes* Executive Producer: Michael Leary* Director:

Your support matters. Help us take action in the fight against cancer: * Donate to the AACR: Fuel innovation by supporting cutting-edge cancer research at 

Take Action: Help Accelerate Progress in Cancer Science and Medicine* Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give* Share this episode: Inspire others by amplifying Karlie’s story of resilience and recovery in the face of cancer* Listen and subscribe: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts, and follow so you never miss an episodeWhat does it take to survive cancer and still make it to the Olympics in a single year?In this inspiring episode of Believe in Progress, we sit down with Karlie Kisha: Olympian, papillary thyroid cancer survivor, and an assistant coach for the Villanova University field hockey team. Karlie takes us inside her incredible journey, from her cancer diagnosis just months before the Paris Olympic Games to representing the U.S. on the world stage.Her story is a masterclass in the power of determination, mindset, and belief in cancer research. Whether you're an athlete, a survivor, or someone in the midst of your own personal challenge, Karlie’s voice will remind you of what’s possible when you face adversity with courage and grace. Episode Highlights:Segment 1: Falling in Love with the Game* Karlie shares her early passion for field hockey, her collegiate journey at the University of Connecticut, and how she set her sights on the Olympics.Segment 2: Diagnosis, Disruption, and Determination* Just months before the Olympics, Karlie was diagnosed with papillary thyroid cancer. She discusses the whirlwind of emotions and the grit it took to keep her Olympic dreams alive.Segment 3: Recovery and Resilience* From surgery to healing to elite-level competition, Karlie reflects on the physical and mental strength required to bounce back and perform on the sport’s biggest stage.Segment 4: Coaching, Mentorship, and the Next Chapter* Now an assistant coach at Villanova, Karlie speaks about finding purpose beyond competition and why giving back means everything.Segment 5: Purpose, Gratitude, and Mental Toughness* Karlie closes with reflections on gratitude, mental health, and how surviving cancer reframed her entire view on life and purpose. Take Action: Support Cancer Research & Survivors* Donate to the AACR: Help advance the research that saves lives at https://AACR.org/Give* Share this episode: Someone in your network needs to hear Karlie’s story, so help us tell it by sharing it with them* Subscribe to Believe in Progress: Never miss a story that could inspire hope and action, you can find us on Apple Podcasts, Spotify, YouTube, or wherever you listenProduction Credits:Host: Mitch StollerGuest: Karlie KishaExecutive Producer: Anthony LopesExecutive Producer: Michael LearyDirector: Anthony LopesCreative Director/Director of Photography: Michael LearyWriter: Anthony Lopes

Want to know how you can take action in the fight against cancer? Help the AACR accelerate progress: - Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at www.AACR.org/Give.- Share this episode: Help amplify the message that strategic investments and scientific breakthroughs can change the future of cancer care.- Listen and subscribe: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts, and follow so you never miss an episode!In this episode of Believe in Progress, recorded live at the 2025 AACR Annual Meeting, we spotlight powerful stories of purpose, partnership, and personal experiences that propel action against cancer. Rodney and Erika McLeod, co-founders of Change Our Future, reflect on their personal cancer journeys and why they’re championing education, youth leadership, and cancer research through their growing partnership with the American Association for Cancer Research (AACR). NFL veteran and former Philadelphia Eagles safety Rodney McLeod shares how the loss of his grandmother to pancreatic cancer shaped his mission, while Erika opens up about her mother’s survivorship and their deep dedication to uplifting the next generation. We’re also joined by Stephen Ryan, President and Chairman of the AACR Foundation and longtime supporter of cancer research. Stephen discusses how personal loss became a catalyst for his advocacy and shares key insights about strategic giving, leadership, and the importance of funding early-stage research. Episode Highlights: Segment 1: Turning Loss into Purpose Rodney and Erika McLeod share how their personal connections to cancer inspired the founding of Change Our Future and their commitment to investing in the next generation. Segment 2: Partnering with the AACR to Inspire Young Scientists The McLeods speak about their involvement with the AACR’s high school program, empowering students to explore STEM and medical research as pathways to impact. Segment 3: Building Confidence Beyond the Classroom Through mentorship, leadership summits, and real-world skills, Change Our Future is equipping underserved youth with tools to succeed in life and career, including in cancer advocacy. Segment 4: Legacy, Strategy, and the Power of Philanthropy Stephen Ryan, President and Chairman of the AACR Foundation, discusses how cancer shaped his family’s legacy and how financial stewardship plays a key role in advancing cancer research. Segment 5: Broadening the Reach of Research Stephen reflects on the AACR’s reputation, the critical need to fund early-career scientists, and why the cancer research ecosystem must expand to reach more communities and have more potential. Production Credits: Host: Mitch StollerGuests: Rodney McLeod, Erika McLeod, Stephen RyanExecutive Producer: Anthony LopesExecutive Producer: Michael LearyDirector: Anthony LopesCreative Director/Director of Photography: Michael LearyWriter: Anthony LopesEditor: Michael LearyAssociate Producer: Heather HollandBelieve in Progress is produced by CollegeCast LLC.

In this powerful episode of Believe in Progress, John Matthews, founder of Ride Hard Breathe Easy, and Jack Owens, a University of Notre Dame student, share their deeply personal journeys to fight lung cancer through action, advocacy, and cycling. Segment 1: A Promise Becomes a MissionJohn shares how a promise to his mother led to Ride Hard Breathe Easy and its first cross-country fundraising ride. Segment 2: A New Generation Joins the RideJack Owens talks about his current 3,600-mile solo ride across the U.S., honoring his grandmother and expanding the organization’s impact. Segment 3: Meeting Patients Where They AreThey discuss how funding helps lung cancer patients with transportation and essential needs, making treatment possible. Segment 4: Breaking the StigmaJohn addresses the stigma around lung cancer and the importance of educating the public about its realities. Segment 5: The Power of Family and CommunityReflections on the role of family, community, and support networks in sustaining the mission.Segment 6: Training, Dedication, and Lessons LearnedJack shares his physical and emotional preparation for the ride, and what keeps him going on the toughest days.  Segment 7: What’s Next for Ride Hard Breathe EasyIf you enjoyed this episode, here is how you can take action to advance cancer research: • Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give• Visit https://www.rhbe.org to learn more about Ride Hard Breathe Easy or to make a donation• Share this episode to raise awareness for cancer patients or with someone you know who might benefit from hearing it• Subscribe to Believe in Progress on Apple Podcasts, Spotify, YouTube, or wherever you listen to podcasts Production CreditsHost: Mitch StollerGuests: John Matthews and Jack OwensExecutive Producer: Anthony LopesExecutive Producer: Michael LearyDirector: Anthony LopesCreative Director/Director of Photography: Michael LearyWriter: Anthony LopesEditor: Michael LearyAssociate Producer: Heather Holland

In this emotional episode of Believe in Progress, host Mitch Stoller, Chief Philanthropic Officer at the AACR, is joined by Joe Krajewski, a father, runner, and advocate who transformed personal tragedy into a powerful mission. After losing his only child, Will, to osteosarcoma in 2016, Joe began running in Will’s memory as part of “Team Will Power,” raising vital funds and awareness in the fight against cancer.You will hear a deeply moving conversation, Joe reflects on love, grief, and legacy, and how a father’s promise has fueled ongoing advocacy, research support, and endurance racing. Whether you’ve experienced loss or simply want to be reminded of the strength of the human spirit, this episode will stay with you.Segment 1: A Father and Son Bonded by RunningJoe shares heartfelt stories about his son Will—their special bond through running, Will’s contagious energy, and their memorable experience running the iconic Hood to Coast relay together.Segment 2: A Life-Altering DiagnosisJust weeks after Hood to Coast, Will was diagnosed with osteosarcoma. Joe recounts the moment of diagnosis, navigating treatments, and the endurance lessons that carried them through.Segment 3: Team Will Power and the Legacy of AdvocacyThe founding of Team Will Power marked a turning point. Joe explains how the team became a tribute to Will and a platform for cancer awareness, resilience, and generosity.Segment 4: Grief, Reflection, and the Endurance to Keep GoingJoe opens up about living with grief, finding healing through running and writing, and how Will’s legacy continues to inspire his advocacy and outlook.Segment 5: The Meaning of ProgressJoe reflects on the power of community, memory, and the AACR’s mission to advance lifesaving science—and what it means to ‘Believe in Progress.’Take Action: Support Childhood Cancer ResearchDonate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/GiveShare this episode: Help spread Will’s story and honor the strength of families impacted by childhood cancer.Subscribe to Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you enjoy podcasts.Production CreditsHost: Mitch StollerGuest: Joe KrajewskiExecutive Producer: Anthony LopesExecutive Producer: Michael LearyDirector: Anthony LopesCreative Director/Director of Photography: Michael LearyWriter: Anthony LopesEditor: Michael LearyAssociate Producer: Heather HollandBelieve in Progress is produced by CollegeCast LLC.

In this special 50th episode of Believe in Progress, Mitch Stoller, the host of Believe in Progress and Chief Philanthropic Officer of the AACR, sits in the guest chair. Special guest host, Anthony Lopes, Esq., the executive producer of Believe in Progress, leads a reflective and inspiring retrospective conversation with Mitch. They discuss the early days of Believe in Progress, at the AACR, as well as moments that moved and transformed. This episode looks back at the voices, lessons, and stories that have shaped the show’s journey, as well as helped the AACR in the fight against cancer. We also hear about why there is still a lot more work to do in the battle against cancer, and why cancer research is so critical to that mission.Segment 1: Why Believe in Progress Matters* Mitch shares the origins of Believe in Progress, inspired by a desire to connect science with humanity and foster wider engagement.Segment 2: Episode One of Believe in Progress to Today* From Lauren Hart to marathon runners to trailblazing scientists, Mitch reflects on the evolution of the show and its mission.Segment 3: Behind the Mic* The guests and moments that left a lasting emotional imprint, including the late Howard Brown and Mitch’s own brother.Segment 4: Science + Philanthropy* Connecting real-world impact with groundbreaking research—and how storytelling builds bridges between them.Segment 5: The Guest Effect* What surprised Mitch most about guests’ honesty, vulnerability, and the unexpected ripple effects of each conversation.Segment 6: Looking Forward* From celebrity voices to younger scientists, Mitch shares his hopes and goals for the next 50 episodes and beyond.Segment 7: Why Progress Needs All of Us* A call to action to subscribe, share, and amplify the message: cancer research saves lives, and everyone has a role to play.Take Action: Support the Fight Against Cancer* Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give* Share this episode: Help amplify the message that strategic investments and scientific breakthroughs can change the future of cancer care* You can show your support by following or subscribing to our show so that you never miss an episode! You can listen and subscribe to Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts. Production Credits:Host: Anthony LopesGuest: Mitch StollerExecutive Producer: Anthony LopesExecutive Producer: Michael LearyDirector: Anthony LopesCreative Director/Director of Photography: Michael LearyWriter: Anthony LopesEditor: Michael LearyAssociate Producer: Heather HollandBelieve in Progress is produced by CollegeCast LLC.

This episode of Believe in Progress brings together two individuals leading global investments in cancer research: Dr. Christiana Bardon of MPM BioImpact and Mark Haefele of UBS Global Wealth Management. Dr. Bardon and Mr. Haefele are uniting science, finance, and philanthropy to accelerate breakthroughs in cancer treatment. Their collaboration has led to the Oncology Impact Fund, a revolutionary approach to investing in biotech innovation and expanding philanthropic support for cancer research.Featured Guests:Dr. Christiana Bardon – Managing Partner, MPM BioImpactDr. Bardon shares how MPM BioImpact has helped launch more than 59 FDA-approved drugs and is driving cutting-edge therapies in oncology. She discusses the philanthropic vision behind the Oncology Impact Fund and the critical role the AACR research grant-giving program plays in supporting young scientists.Mark Haefele – Chief Investment Officer, UBS Global Wealth ManagementMark discusses UBS’s commitment to purposeful investing, the genesis of the Oncology Impact Fund, and how clients responded to the idea of aligning financial returns with social good through impact investing.Key Topics:- The intersection of financial investment and cancer innovation- How impact investing can fund lifesaving research- The origins and structure of the Oncology Impact Fund- Why philanthropy and venture capital must work together- The role of AACR grants in nurturing the next generation of researchersTake Action: How You Can Support the Fight Against Cancer - Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give- Share this episode: Help amplify the message that strategic investments and scientific breakthroughs can change the future of cancer care- Listen and subscribe: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcasts and make sure to follow/subscribe to our show so that you never miss an episode!Cancer Research Saves Lives®Production Credits:Host: Mitch StollerExecutive Producer: Anthony LopesExecutive Producer: Michael LearyDirector: Anthony LopesCreative Director/Director of Photography: Michael LearyWriter: Anthony LopesEditor: Michael LearyAssociate Producer: Heather HollandBelieve in Progress is produced by CollegeCast LLC.

This special episode of Believe in Progress, recorded live at the AACR Annual Meeting 2025 in Chicago, features two compelling conversations that spotlight the human side of cancer research. From confronting rare diagnoses to reshaping clinical tria...

This special episode of Believe in Progress, recorded live at the 2025 AACR Annual Meeting in Chicago, features dynamic conversations with researchers, clinicians, entrepreneurs, and student scholars, each contributing uniquely to the fight against cancer. From breakthrough diagnostics to trailblazing health services research, our guests share their stories of science, innovation, and hope.Featured GuestsDr. Marija Plodding – CEO and Co-Founder of ARTIDISDr. Plodinec discusses how her background in physics led to a revolutionary approach in cancer diagnostics through nano-mechanical phenotyping. Learn how ARTIDIS is using atomic force microscopy to analyze tissue stiffness and improve treatment precision for solid tumors.Dr. Andrew Chapman – Director, Sidney Kimmel Cancer Center, Jefferson HealthA leader in geriatric oncology and care delivery, Dr. Chapman emphasizes the importance of safe, high-quality care for all patients, especially older adults. He also reflects on the AACR’s impact as a convening force for breakthrough science.Izzy Wiener & Isaac Silverman – Student Researchers, Yeshiva UniversityThese future cancer researchers discuss their work in bioinformatics and molecular biology, presenting posters at the AACR Annual Meeting and sharing how their experiences shape their aspirations in medicine and research.Aaron Shaykevich – Scholar-in-Training Awardee & Incoming Medical Student, SUNY UpstateAaron shares how his research into novel cancer markers is informed by his passion for public health and economics. He emphasizes the role of community insights and AI in future research directions.Take Action: How You Can Support the Fight Against Cancer* Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give (https://aacr.org/Give)* Share this episode: Help amplify the message that bold ideas and cross-disciplinary thinking can change the future of cancer care* Listen and Subscribe: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcastsCancer Research Saves Lives® Production Credits: * Host: Mitch Stoller* Executive Producer: Anthony Lopes* Executive Producer: Michael Leary* Director: Anthony Lopes* Creative Director/Director of Photography: Michael Leary* Writer: Anthony Lopes* Editor: Michael Leary* Associate Producer: Heather HollandBelieve in Progress is produced by CollegeCast LLC.  Check out more episodes: https://AACR.org/BelieveInProgress (https://aacr.org/BelieveInProgress)

What happens when deep science meets bold cancer-fighting innovation? In this episode of Believe in Progress, we sit down with Dr. Ajit Singh—Managing Director at Artiman Ventures and a Trustee of the AACR Foundation—for a compelling conversation about the technologies and ideas shaping the future of cancer care.With decades of experience leading both Fortune 500 healthcare companies and high-impact startups, Dr. Singh brings a unique perspective to the intersection of oncology, diagnostics, data science, and global health. From early detection and precision diagnostics to equitable access in underserved communities, his insights offer a powerful look at what’s next in the fight against cancer.In this episode, you’ll learn:* Why diagnostics and imaging are essential to improving patient outcomes* How venture capital is accelerating lifesaving cancer innovations* What it takes to bring bold ideas to market—and make them accessible globally* Why Dr. Singh believes in continuous learning, curiosity, and collaboration* What drives his commitment to the AACR Foundation’s missionWhether you're a scientist, entrepreneur, clinician, or advocate, this episode will inspire you to think bigger about what's possible in cancer care.Take Action: How You Can Support Cancer Research* Learn more about Dr. Ajit Singh’s work: Explore the ventures and companies he supports that are reshaping cancer diagnostics and care* Donate to the AACR: Fuel lifesaving innovation by supporting cutting-edge cancer research at https://AACR.org/Give* Share this episode: Help amplify the message that bold ideas and cross-disciplinary thinking can change the future of cancer care* Subscribe and listen: Find Believe in Progress on Apple Podcasts, YouTube, Spotify, or wherever you get your podcastsCancer Research Saves Lives® Production Credits: * Host: Mitch Stoller* Guest: Dr. Ajit Singh* Executive Producer: Anthony Lopes* Executive Producer: Michael Leary* Director: Anthony Lopes* Creative Director/Director of Photography: Michael Leary* Writer: Anthony Lopes* Editor: Michael Leary* Associate Producer: Heather HollandBelieve in Progress is produced by CollegeCast LLC.  Check out more episodes: https://AACR.org/BelieveInProgress

In this powerful and deeply personal episode of Believe in Progress, the podcast presented by the American Association for Cancer Research Foundation, host Mitch Stoller sits down with Chef AJ—renowned plant-based chef, bestselling author, and host of the popular YouTube channel "Healthy Living with Chef AJ." With over 47 years of experience in whole-food, plant-based nutrition, Chef AJ has long championed the power of healthy eating.But in early 2023, her journey took an unexpected turn with a stage 3 lung cancer diagnosis—an experience she publicly shared for the first time in November 2024. Now, Chef AJ is using her platform to speak candidly about cancer, nutrition, and what it means to live with purpose through adversity.This conversation explores:• Chef AJ’s transformation from “junk-food vegan” to whole-food advocate• Her surprising cancer diagnosis and the emotional aftermath• The evolving role of nutrition in cancer prevention and healing• How community, mindset, and hope fuel her journey today• What she’s learned from survivors, support groups, and sharing her platformWhether you’re navigating cancer, exploring a plant-based lifestyle, or searching for stories of resilience and hope—this is an episode you won’t want to miss.Don't forget to visit Chef AJ’s website and YouTube channel, to explore her books, including "Unprocessed" and "The Secrets to Ultimate Weight Loss," and access her “Thriving in the Face of Cancer” video series.If this episode moved you, here’s how you can make a difference:• Support cancer research by donating at AACR.org• Subscribe and leave a review on Apple Podcasts, YouTube, or wherever you listen• Share this episode with someone who might benefit from hearing Chef AJ’s storyProduction Credits:• Host: Mitch Stoller• Guest: Chef AJ• Executive Producer: Anthony Lopes• Executive Producer: Michael Leary• Associate Producer: Heather Holland• Director: Anthony Lopes• Creative Director/Director of Photography: Michael Leary• Editor: Michael LearyThis episode is produced by CollegeCast LLC.

How can new approaches to early detection make a difference for children at risk of rare cancers? In this episode of Believe in Progress, brought to you by the American Association for Cancer Research (AACR) Foundation, host Mitch Stoller speaks with Dr. Kris Ann P. Schultz, a leading pediatric oncologist and Scientific Director of Cancer and Blood Disorders at Children's Minnesota.Dr. Schultz shares her groundbreaking work on DICER1-related cancers and how early diagnosis, surveillance, and collaboration with patients and families are transforming the field of pediatric oncology. From research-driven strategies to personal stories of survival, this episode explores how science and compassion intersect to save lives.Whether you're a healthcare professional, a caregiver, or an advocate for pediatric cancer research, this episode offers vital insights into how research is reshaping the future of childhood cancer care.In this episode, you’ll hear:* How Dr. Schultz’s personal drive led her into pediatric oncology* Why DICER1 research is critical for rare childhood cancers* How early detection and surveillance guidelines are changing lives* The vital role patients and families play in advancing research* Why survivorship care is essential for long-term wellness* How you can help drive progress in pediatric cancer researchTimestamps:* 00:00 Introduction and Mission Statement* 00:15 Welcome to Believe in Progress* 00:56 Meet Dr. Kris Ann Schultz* 01:26 Dr. Schultz’s Career and Contributions* 07:41 The Importance of Survivorship Care* 12:49 Understanding ER One and DICER1* 16:18 Early Detection and Surveillance Guidelines* 22:32 Challenges and Future Directions* 29:10 Conclusion and Wrap-upAdditional information and contact information:* In 2024, the PPB/DICER1 Registry published updated DICER1 testing and surveillance guidelines in the journal of Clinical Cancer Research. This analysis demonstrated the impact of surveillance in PPB and Sertoli Leydig cell tumor and led to a recommendation for earlier initiation of ovarian surveillance in girls and young women with germline DICER1 variants. * READ MORE: https://aacrjournals.org/clincancerres/article/30/24/5681/750430/DICER1-Related-Tumor-Predisposition-Identification (https://aacrjournals.org/clincancerres/article/30/24/5681/750430/DICER1-Related-Tumor-Predisposition-Identification)* Early detection efforts for individuals with DICER1-related tumor predisposition include patient and family education and age-specific imaging recommendations. * In rare cancers, every journey matters! Individuals impacted by these rare conditions are encouraged to learn more about DICER1 and to consider participation in efforts to advance our understanding of optimal treatments.* To contact the PPB/DICER1 and OTST Registries, please email dicer1@childrensmn.org (mailto:dicer1@childrensmn.org).* To learn more about the PPB/DICER1 Registry please visit www.ppbregistry.org (http://www.ppbregistry.org/)* To learn more about the OTST Registry please visit www.otstregistry.org (https://www.otstregistry.org/)Learn more and take action:* Visit aacr.org (https://www.aacr.org) to donate and support pediatric cancer research* Subscribe and share this episode to spread awareness* For more episodes, visit

What does it take to turn a scientific discovery into a treatment that changes lives? On this episode of Believe in Progress, the podcast brought to you by the American Association for Cancer Research (AACR) Foundation, host Mitch Stoller talks with Dr. William Pao, an esteemed physician-scientist, executive leader, and author of the new book Breakthrough: The Quest for Life-Changing Medicines. Dr. Pao is the Chief Executive Officer of Revelio Therapeutics, Inc. and previously led Global Product Development at Pfizer, overseeing the clinical development and regulatory advancement of innovative medicines. With a distinguished career spanning leadership roles at Pfizer, Roche, and Vanderbilt University, Dr. Pao has been at the forefront of oncology research and drug development. In this episode, we explore:* The complex journey of drug discovery and the biggest challenges scientists face* The unexpected twists and groundbreaking moments behind revolutionary treatments* The role of collaboration and innovation in drug development* The future of cancer research and how scientific advancements are shaping patient care* The critical need for continued investment in cancer researchDr. Pao’s work offers a rare glimpse into the process of creating lifesaving medicines, and his book Breakthrough takes readers behind the scenes of eight transformative treatments. Whether you’re a patient, a caregiver, a scientist, or someone passionate about the future of medicine, this is an episode you won’t want to miss. Episode Highlights: * Dr. Pao’s journey – From academic research to leading global pharmaceutical development, how his career evolved to focus on oncology and lifesaving treatments* The story behind Breakthrough – Why Dr. Pao wrote this book and what readers can learn about the real process of drug discovery* The science of innovation – The unexpected challenges and pivotal moments that shape medical breakthroughs* The future of cancer research – The biggest opportunities and challenges in developing next-generation therapies* Collaboration & research – How scientists, regulators, and patients work together to bring treatments to market* Why cancer research needs support – The importance of continued investment in research to drive progress in oncology and beyondTake Action: How You Can Support Cancer Research * Read Dr. Pao’s book: Breakthrough: The Quest for Life-Changing Medicines – A must-read for anyone interested in the future of medicine* Donate to the AACR: Support groundbreaking cancer research by visiting AACR.org/Donate  * Share this episode: Help spread awareness about the power of research and innovation in the fight against cancer* Subscribe & listen: Find Believe in Progress on Apple Podcasts, YouTube, Spotify,