Welcome to Cardiology Today – Recorded November 19, 2025. This episode summarizes 5 key cardiology studies on topics like heart failure and stroke. Key takeaway: ECG Abnormalities Predict Heart Failure Risk. Article Links: Article 1: Isolated non-specific electrocardiographic ST-T abnormalities and risk of incident heart failure and its subtypes. (Heart (British Cardiac Society)) Article 2: Estimating 5-year absolute risk of cardiovascular disease using routinely collected electronic medical records from Australian general practices. (Heart (British Cardiac Society)) Article 3: Comparing diagnostic tools for heart failure with preserved ejection fraction across community and clinical cohorts. (Heart (British Cardiac Society)) Article 4: Therapy gaps for patients with heart failure and reduced kidney function: A prospective cohort study. (ESC heart failure) Article 5: Impact of Left Atrial v-Wave Following Mitral Edge-to-Edge Repair on Survival: The MITRA-PRO Registry. (Journal of the American Heart Association) Full episode page: https://podcast.explainheart.com/podcast/ecg-abnormalities-predict-heart-failure-risk-11-19-25/ Featured Articles Article 1: Isolated non-specific electrocardiographic ST-T abnormalities and risk of incident heart failure and its subtypes. Journal: Heart (British Cardiac Society) PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41249037 Summary: Isolated non-specific S. T. T. abnormalities on electrocardiograms were found to be associated with an increased risk of incident coronary heart disease and stroke in participants free of these conditions at baseline. This study also found that these abnormalities were linked to an increased risk of incident heart failure and its subtypes. Data showed that these specific electrocardiographic patterns, defined by Minnesota E. C. G. classification, independently predicted future development of heart failure, including both heart failure with preserved ejection fraction and heart failure with reduced ejection fraction. These findings establish a prognostic role for isolated non-specific S. T. T. abnormalities in identifying individuals at risk for future cardiovascular events and heart failure. Article 2: Estimating 5-year absolute risk of cardiovascular disease using routinely collected electronic medical records from Australian general practices. Journal: Heart (British Cardiac Society) PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41249035 Summary: This study demonstrated the feasibility and performance of using routinely collected electronic medical records from Australian general practices to estimate the 5-year absolute risk of cardiovascular disease. Researchers found that integrating primary care electronic medical record data, specifically from the New South Wales Health Lumos program, provided a viable approach for cardiovascular risk prediction. The study successfully utilized data from 680 general practices to assess the predictive capability of these records. These findings indicate that Australian healthcare systems can effectively leverage existing electronic medical records for robust cardiovascular disease risk estimation, comparable to methods used in the U. S. A. and U. K. Article 3: Comparing diagnostic tools for heart failure with preserved ejection fraction across community and clinical cohorts. Journal: Heart (British Cardiac Society) PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41249034 Summary: This study demonstrated the comparative diagnostic accuracy of several tools for heart failure with preserved ejection fraction (H. F. pEF) across community and clinical cohorts. Researchers found that the Heart Failure Association-P. E. F. F. and H. two F. P. E. F. Scores showed differing diagnostic performance when compared against inclusion criteria from sodium-glucose cotransporter-two inhibitors trials and age-adjusted N-terminal pro B-type natriuretic peptide. The data provided clarification on the strengths and limitations of each diagnostic ap