Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

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Dr. Kara Fitzgerald

207 episodes

4 days ago

We explore how discoveries in cardiology led to this technology, what early clinical studies are showing, and why source and preparation are critical when evaluating any exosome-based approach. A clear, grounded look at a fast-moving field for clinicians who want to understand what’s real, what’s emerging, and what deserves attention next.

Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/

GUEST DETAILS Alisa Lask is the CEO of Rion Aesthetics, where she is driving innovation in regenerative aesthetics with platelet-derived exosomes and leading research in areas like hair restoration and skin appearance. She also oversees (plated)™ Skin Science, a medical-grade exosome skincare line distributed through aesthetic providers.

Alisa previously held senior roles at Galderma, Allergan, Zimmer-Biomet, and Eli Lilly, and she serves on the Board of Directors for CollPlant. She holds an MBA from the University of Michigan and is also a nationally competitive show-jumping equestrian involved in dog rescue initiatives.

THANKS TO OUR SPONSOR

(plated)™ Skin Science: http://platedskinscience.com/

Plated Skin Science translates the discovery of Dr. Atta Behfar, M.D., Ph.D., Director of Mayo Clinic’s Van Cleve Cardiac Regenerative Medicine Program into the first shelf-stable skincare line using regenerative, platelet-derived exosomes. These aren’t generic exosomes; they’re a specific class shown in peer-reviewed trials to regenerate skin's appearance by improving the look of wrinkles, pigmentation, luminosity, and overall skin quality. It’s an elegant approach to visible signs of skin aging, recognized by Time as a Best Invention of 2024 and now used in more than 2,000 medical practices. Learn more at http://platedskinscience.com/

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Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

Health & Fitness

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Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/

THANKS TO OUR SPONSOR

(plated)™ Skin Science: http://platedskinscience.com/

CONNECT with DrKF

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

Health & Fitness

Episodes (20/207)

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Platelet-Derived Exosomes in Aesthetics: Data, Safety, and Real-World Use Cases

Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/

THANKS TO OUR SPONSOR

(plated)™ Skin Science: http://platedskinscience.com/

CONNECT with DrKF

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

4 days ago

46 minutes 28 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

The Oral Microbiome: The Hidden Biomarker Driving Aging, Fertility & Systemic Inflammation

Functional dentistry is emerging as a powerful missing link in systems-based care. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald sits down with Staci Whitman, DMD, IFMCP, a leading voice in functional pediatric dentistry and co-founder of the upcoming Institute for Functional Dentistry. Together, they explore how the oral microbiome, airway health, saliva, hormones, nutrition, and stress physiology shape systemic inflammation, chronic disease risk, and long-term health outcomes.

You’ll learn how to recognize oral contributors to gut issues, autoimmunity, cardiometabolic disease, cognitive decline, sleep disorders, and more—plus practical tools you can use right away in a medical setting, including a simple five-question airway and breathing screener. If you’re looking to expand your longevity and whole-body health framework, this conversation offers clear, actionable insights you won’t want to miss.

Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/

GUEST DETAILS Dr. Staci Whitman is a board-certified pediatric and functional dentist and co-founder of the Institute for Functional Dentistry (IFD). She integrates the oral microbiome, airway and sleep health, nutrition, hormones, and early childhood development into modern dental care. She also founded Bloom Kids Dentistry and has an upcoming book on the oral microbiome.

Website: http://doctorstaci.com

THANKS TO OUR SPONSORS

DIAMOND

DUTCH: https://dutchtest.com/for-providers

Biotics Research: https://bit.ly/2IHK6Xd

GOLD TimeLine Nutrition: https://tinyurl.com/bdzx2xms

Vibrant Wellness: https://www.vibrant-wellness.com/

EXCLUSIVE OFFERS FROM OUR SPONSORS

OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA

Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. http://mitoq.com/drkara

*CONNECT with DrKF*

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz

Instagram: https://www.instagram.com/drkarafitzgerald/

Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

3 weeks ago

1 hour 19 minutes 34 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

The Hidden Immune Signal Accelerating Aging & the Beta-Glucan That Fixes It

Beta-glucans might be one of the most overlooked levers in immune resilience, and that has major implications for longevity. Talking with my long-time friends and colleagues Drs. Bob Rountree and Chris D’Adamo reminded me just how powerful this molecule truly is. The clinical reach here is stunning, from immune aging and cancer support to vaccine response, gut–brain effects, and overall resilience. What struck me most is how beta-glucans help the innate immune system respond more effectively over time, from overtraining and chronic infections to vaccine responsiveness. Clinicians really need this on their radar. I think you’re going to find this conversation eye-opening. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Bob Rountree, MD, is a leading figure in integrative and functional medicine with more than 40 years of clinical experience. Medical Director of Boulder Wellcare and long-time IFM faculty, he is widely published and a respected educator in personalized medicine, botanical therapies, and immune health.

Chris D’Adamo, PhD, is a research scientist and epidemiologist focused on how nutrition, lifestyle, and environmental factors influence health. An Assistant Professor at the University of Maryland School of Medicine, he has led numerous clinical studies, published widely, and is a trusted advisor and educator in integrative and lifestyle medicine.

THANKS TO OUR SPONSOR

BetterWay Health (Consumers) BWHLabs (Practitioners) WEBSITE: http://bwhlabs.com/kara

EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS

Book a practitioner call and receive a complimentary bottle of beta-glucan to try personally or with a patient at http://bwhlabs.com/kara

CONNECT with DrKF

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

1 month ago

1 hour 5 minutes 49 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

From Hot Flashes to Healthspan: The FxMed Guide to Hormones & Longevity

In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald sits down with hormone and women’s health expert Dr. Carrie Jones to explore the powerful connection between mitochondrial health and women’s hormones. Together, they unpack how mitochondrial function influences hormone balance, metabolism, energy, mood, and resilience, especially during perimenopause and menopause. Dr. Jones shares practical, evidence-based strategies to support mitochondrial health for optimal hormonal balance, improved sleep, and emotional well-being.

Listeners will gain actionable insights into functional medicine approaches to women’s hormone health, including how mitochondrial vitality can help ease hormonal transitions and enhance longevity.

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Dr. Carrie Jones, ND, FABNE, MPH, MSCP is an internationally recognized expert in women’s health and hormones. Known as the “Queen of Hormones,” she’s a naturopathic physician, educator, and Chief Medical Officer at NuEthix Formulations. With over 20 years in the field, Dr. Jones has shaped hormone education through her work with major functional labs and her hit podcast, Hello Hormones.

Email: drjones@drcarriejones.com Website: https://www.drcarriejones.com/ THANKS TO OUR SPONSORS

DIAMOND

DUTCH: https://dutchtest.com/for-providers

Biotics Research: https://bit.ly/2IHK6Xd

GOLD

TimeLine Nutrition: https://tinyurl.com/bdzx2xms

Vibrant Wellness: https://www.vibrant-wellness.com/

EXCLUSIVE OFFERS FROM OUR SPONSORS

OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA

Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. https://tinyurl.com/4f8t7jt6

*CONNECT with DrKF*

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz

Instagram: https://www.instagram.com/drkarafitzgerald/

Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

1 month ago

1 hour 4 minutes 16 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Guide to Building a Sustainable Concierge Longevity Practice

Dr. Kara Fitzgerald sits down with Dr. Brooke Stubbs, an internal and lifestyle medicine physician who transitioned from hospital medicine to a concierge model focused on prevention and personalization. Together, they discuss how to design a practice that supports both patients and practitioners, from efficient systems and appropriate pricing to functional lab integration. Dr. Stubbs explains how Vibrant Wellness helps streamline diagnostics and ensure consistent, high-quality care, offering real-world insights for clinicians ready to evolve their model.

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS

Dr. Brooke Stubbs is a double board-certified physician in Internal and Lifestyle Medicine with a master’s in nutrition from Columbia University. As founder of Rooted Femme, a concierge practice in Austin, she helps women achieve better health through lifestyle-based care. She’s a national speaker, retreat creator, and advocate for integrating science, art, and compassion into modern medicine.

Website: https://www.rootedfemme.com/

LinkedIn Profile: https://www.linkedin.com/in/brookestubbsmd/

THANKS TO OUR SPONSOR

SPONSOR: Vibrant Wellness http://vibrant-wellness.com/drfitzgerald

Vibrant Wellness’ innovative testing panels identify key imbalances in areas like nutrition, hormones, toxins, and the gut microbiome—so you can take targeted steps toward optimal wellness. Discover the possibilities and become a provider or connect with one near you at http://vibrant-wellness.com/drfitzgerald

CONNECT with DrKF

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

2 months ago

36 minutes 28 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Reversing Aging: Screening, Wearables & What To Do Now

Dr. Kara Fitzgerald talks with Sergey Young, founder of the Longevity Vision Fund and XPRIZE board member, about the future of aging medicine. Hear how AI, wearables, new diagnostics, and early screening are making longevity solutions more practical, affordable, and clinically relevant for functional medicine practitioners.

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Sergey Young is a longevity investor, author, and visionary committed to extending healthy lifespans for one billion people. He co-founded the BOLD Longevity Growth Fund, wrote the bestseller The Science and Technology of Growing Young, and serves on the boards of XPRIZE and AFAR.

Website: https://sergeyyoung.com/ Follow Sergey: @sergeyyoung200

THANKS TO OUR SPONSORS

DIAMOND

DUTCH: https://dutchtest.com/for-providers

GOLD

Vibrant Wellness: https://www.vibrant-wellness.com/

TimeLine Nutrition: https://tinyurl.com/bdzx2xms

EXCLUSIVE OFFERS FROM OUR SPONSORS

Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. https://tinyurl.com/4f8t7jt6

OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA

CONNECT with DrKF - Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz

Instagram: https://www.instagram.com/drkarafitzgerald/

Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

2 months ago

37 minutes 17 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Aging & Hair Loss Explained: OS-01’s Science-Backed Approach

Hair loss is more than cosmetic. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald explores new research on the OS-01 peptide and its role in targeting senescent cells. Learn how peptide therapy compares to minoxidil, and how hormones, thyroid health, stress, UV exposure, and the scalp microbiome all play a role in thinning hair. Carolina Reis Oliveira, PhD, co-founder of OneSkin, shares insights on how polyphenols, prebiotics, and integrative strategies can support healthier growth.

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Carolina Reis Oliveira, PhD - OneSkin Co-Founder & CEO

Carolina Reis Oliveira, PhD, is the CEO and co-founder of OneSkin and an advocate for healthy aging. With a doctorate in immunology, she moved from Brazil to Silicon Valley to pursue her vision of using science to prevent age-related diseases. At OneSkin, she leads pioneering research on aging biology, including the development of the proprietary OS-01 peptide, the first scientifically proven to reverse skin’s biological age.

THANKS TO OUR SPONSOR

OneSkin: http://oneskin.co/DRKARA

EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS

Interested in reclaiming your roots and addressing hair thinning? Visit https://oneskin.co/DRKARA for 15% off your purchase of OneSkin’s OS-01 HAIR peptide scalp serum.

CONNECT with DrKF

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

3 months ago

46 minutes 43 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

The Bile Acid Imbalance Accelerating Aging: How to Detect & Fix It

Have you ever struggled to understand why some patients just don’t respond as expected, even when you’re following all the usual gut protocols? In this episode, I sat down with Dr. Tom Fabian, who breaks down the latest insights from StoolOMX and GI-MAP testing and shows us how to put them into practice for our most complex cases. We dive into how identifying specific types of inflammation, bile acid patterns, and microbial imbalances can guide more precise interventions, whether it’s introducing fiber, addressing biofilms, or supporting secondary bile acid production. Dr. Fabian makes the science practical, helping us see not just what’s happening in the gut, but what to do about it in real-world clinical settings. ~DrKF

FOLLOW ALONG WITH THE CONVERSATION!

Curious about the StoolOMX Add-On to GI-MAP? Head to http://tinyurl.com/StoolOMX to download the StoolOMX Reference Guide to better understand results and create effective, actionable protocols

Listeners, join me and Dr. Tom Fabian for a free webinar on October 23rd 2025 and get your questions answered on all things on all things bile acids, pattern recognition on functional stool testing and precision-based interventions for optimal gut health and longevity. Register here: https://tinyurl.com/ydzsh6y6

Check out the show notes at www.drkarafitzgerald.com/fxmed-podcast/ for all the relevant links and resources.

GUEST DETAILS Thomas Fabian, PhD, CNTP

Email: tom.fabian@diagnosticsolutionslab.com

Dr. Tom Fabian, PhD, is a translational scientist focused on applying microbiome research in functional and integrative medicine. He serves as a consultant and science advisor with Diagnostic Solutions Laboratory, sits on the Science Advisory Board at Designs for Health, and is a certified Nutrition Therapy Practitioner.

THANKS TO OUR SPONSOR

Diagnostic Solutions Laboratory: https://tinyurl.com/2shv9jth Phone: 877-485-5336

CONNECT with DrKF

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

3 months ago

56 minutes 18 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Why Functional Medicine Is the Future of Longevity

Can functional medicine unlock the secrets to healthy aging? In this special preview of the Functional Medicine is Longevity Medicine™ Masterclass happening on September 17- September 19, 2025, Dr. Kara Fitzgerald sits down with three leading voices in medicine and research:

- Dr. Bob Rountree: functional medicine pioneer in integrative approaches to health

- Dr. Dale Bredesen: internationally recognized expert on Alzheimer’s prevention and reversal

- Dr. Charles Serhan: Harvard researcher on inflammation resolution and aging biology

Together, they explore how functional medicine reframes longevity by addressing root causes, supporting cognitive health, and resolving chronic inflammation.

Whether you’re a clinician, health professional, or simply passionate about living longer and healthier, this conversation offers a glimpse into the science and practical applications that are transforming longevity medicine.

WATCH NOW TO LEARN:

- Why functional medicine is central to extending healthspan - The latest insights on Alzheimer’s prevention and brain health - How inflammation resolution impacts aging and chronic disease - What to expect in the full Functional Medicine is Longevity Medicine™ Masterclass

Learn more & register for the Masterclass here: www.functionalmedicineislongevitymedicine.com

THANKS TO OUR SPONSORS

DIAMOND

DUTCH: https://dutchtest.com/for-providers

Biotics Research: https://www.bioticsresearch.com/

GOLD

TimeLine Nutrition: https://tinyurl.com/bdzx2xms

Vibrant Wellness: https://www.vibrant-wellness.com/

EXCLUSIVE OFFERS FROM OUR SPONSORS

OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA

Discover why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. https://tinyurl.com/4f8t7jt6

4 months ago

55 minutes 16 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Why Centenarians Are Defying Science: Secrets to Living 100+

It was a pleasure to sit down with Dr. Nir Barzilai for a conversation that turned out to be both lively and thought-provoking. His decades of research on centenarians, biological age, and the hallmarks of aging have shaped how we think about longevity—and what’s possible when we start targeting aging itself, not just individual diseases.

We get into the science behind why some people live 20–30 years longer and healthier, and what it means to measure the biological age of individual organs. But we also hit a few sparks—especially when it comes to nutraceuticals and the role of metformin in prevention. I don’t agree with everything you’ll hear, and I followed up with Dr. Barzilai afterward to unpack some of the more provocative claims. We may just need a second round for this one... stay tuned.

Check out the show notes at www.drkarafitzgerald.com/fxmed-podcast/ for all the relevant links and resources. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Nir Barzilai M.D. Director of the Einstein Institute for Aging Research Professor of Medicine and Genetics President of the Academy for Health & Lifespan Research

Website: https://einsteinmed.edu/faculty/484/nir-barzilai

Email: nir.barzilai@einsteinmed.edu

Dr. Nir Barzilai is a pioneer in aging science, known for his work on centenarians, the biology of aging, and the TAME trial. He is Director of the Institute for Aging Research at Albert Einstein College of Medicine and author of Age Later and has published over 330 papers.

THANKS TO OUR SPONSORS

DIAMOND

DUTCH: https://dutchtest.com/for-providers

Biotics Research: https://www.bioticsresearch.com/

GOLD Vibrant Wellness: https://www.vibrant-wellness.com/

OneSkin: http://oneskin.co/DRKARA

EXCLUSIVE OFFERS FROM OUR SPONSORS

Why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy.https://tinyurl.com/4f8t7jt6

OneSkin: Get 15% off OneSkin with the code DRKARA at oneskin.co/DRKARA

CONNECT with DrKF

Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz

YouTube: https://tinyurl.com/hjpc8daz

Instagram: https://www.instagram.com/drkarafitzgerald/

Facebook: https://www.facebook.com/DrKaraFitzgerald/

DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You Practitioner Training Program: https://www.drkarafitzgerald.com/trainingyyi/

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

4 months ago

1 hour 22 minutes 19 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

The Science-Backed Bitter Compound That Mimics GLP-1 (No Injections Needed!)

I’ve been watching the science behind Calocurb evolve over the last year, and I have to say—this is one of the most exciting clinical tools I’ve seen emerge in the metabolic space in quite some time. A hops-derived compound that stimulates endogenous GLP-1, CCK, and PYY—without a prescription or injection? That’s a big deal, especially for patients struggling with appetite regulation, weight plateaus, or the aftermath of GLP-1 discontinuation.

In this episode, I sit down with Sarah Kennedy, founder of New Zealand-based Calocurb, to talk about the years of government-funded research that led to this discovery, the remarkable clinical outcomes they’ve seen so far, and how I’ve personally used it in my practice with excellent results. If you’re looking for science-backed, natural strategies to support appetite control, fasting, or GLP-1 transitions—this one’s worth a listen. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Sarah Kennedy, Founder and CEO of Calocurb Ltd.

Email: sarah.kennedy@calocurb.com LinkedIn: https://www.linkedin.com/in/sarah-kennedy-0a840b13/

Sarah Kennedy, BVSc, is a veterinarian and health industry leader with 20+ years in nutrition science and innovation. Now CEO of Calocurb, she brings a unique perspective on natural GLP-1 activation—bridging plant-based research, gut physiology, and clinical application.

THANKS TO OUR SPONSOR: Calocurb

EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS

Manage cravings and feel full faster with Calocurb, a 100% natural capsule that supports healthy weight management. Visit http://calocurb.com/drkara10 and use code DRKARA10 at checkout.

CONNECT with DrKF

Join Dr. Kara Fitzgerald and leading experts *LIVE on Sept 17–19, 2025* for a free virtual Masterclass on redefining healthcare & longevity through the lens of science-backed, systems-based approach. Register now: https://www.functionalmedicineislongevitymedicine.com/

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5 months ago

53 minutes 6 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

10 Year Anniversary: What I Learned After 200+ Conversations with the Best Minds in FxMed

In this very special episode, I have the privilege of turning the tables on Dr. Kara Fitzgerald as we celebrate 10 years of the New Frontiers podcast. I’ve been honored to walk alongside Kara on much of this journey—as a colleague, a collaborator, a mentee, and a friend—and it’s been incredible to witness the evolution of both her work and the field itself.

Together, we reflect on the stories, science, and people who have shaped this podcast—and the remarkable growth of epigenetics, personalized medicine, and functional medicine along the way. From early conversations around methylation and aging to hosting pioneers like Dr. Jeff Bland, Dr. Sidney Baker, and Dr. Charles Serhan, New Frontiers has become a living archive of how this field has moved forward.

As we talked about during the conversation: “Everybody is a piece of this ecosystem, and everybody has their role... It’s really cool to be part of that community.” This episode is a celebration of that collective journey—and a look at where we’re headed next. ~Romilly Hodges MS CNS

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

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5 months ago

1 hour 17 minutes 27 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Dead Mitochondria Might Be Fueling Cardiovascular Aging — Here’s The Fix

This is a really exciting conversation with Dr. Davide D’Amico from Timeline, where we’re taking a closer look at Urolithin A and heart health. It should come as no surprise that this mitochondrial wonderkin of a nutrient is showing promise here—especially when you consider that 40% of the heart’s weight is mitochondria. That’s an extraordinary factoid, and one that really shifts how we think about aging in the cardiovascular system.

What’s particularly compelling in this new preclinical research is that restoring mitochondrial function may do more than just improve ejection fraction. It may also have ripple effects on other hallmarks of aging—like chronic inflammation, cellular stress signaling, and impaired autophagy. I’m thrilled Timeline is continuing to invest in both preclinical and clinical research on this front—and yes, I’m totally nerding out over what they’re up to. ~DrK

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Davide D'Amico, PhD: Director of Discovery and Translational Research at Timeline.

With over 15 years of experience in mitochondrial and aging biology, he contributed to developing Urolithin A as a science-backed, clinically validated nutritional product to enhance mitochondrial and muscle health.

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6 months ago

47 minutes 27 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Why Human-Centered AI Is the Future of Medicine & Mental Wellness

This episode is a little different from what we usually cover on New Frontiers, but it’s one I couldn’t wait to bring to you. I’ve been thinking a lot about how we—as clinicians—are supposed to keep up in this era of high-throughput technology. We’re swimming in data: labs, multi-omics, diet logs… and an ever-growing stream from wearables. There’s just so much coming at us, and too often, we’re awash in a sea of information without adequate interpretive power.

That’s why this conversation with Dr. Rana el Kaliouby felt so important. She’s not just an AI scientist—she’s a visionary and a total badass. She’s building technology that doesn’t just process data, but actually helps us become better clinicians and better humans. We get into the ethics, the potential, the parenting implications—and yes, a personal story about a tragedy in my own hometown that made this all hit very close to home. This one’s powerful, and I hope it sparks the same questions and inspiration for you as it did for me. ~DrKF

TRIGGER WARNING

This episode touches on sensitive topics, including gun violence and suicide, in the context of empathy, mental health, and technology. If you or someone you know is struggling, please seek help. We share this with care and hope it offers support and perspective.

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Dr. Rana el Kaliouby: http://www.ranaelkaliouby.com

Managing Partner, Blue Tulip Ventures: http://www.bluetulip.vc

Host, Pioneers of AI Podcast: https://www.pioneersof.ai/

Author of Girl Decoded

Dr. Rana el Kaliouby is an Egyptian-American AI scientist, entrepreneur and investor. She is co-founder and Managing Partner of Blue Tulip Ventures, where she invests in startups building Human-Centric AI, and host of the Pioneers of AI podcast. Prior to that, Rana founded her company Affectiva out of MIT, where she pioneered the field of Emotion AI, and successfully exited the company in 2021. She holds a Ph.D. from the University of Cambridge and a Post Doctorate from MIT.

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6 months ago

1 hour 11 minutes 26 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Legal Pitfalls That Could Destroy Your Practice & How to Avoid Them

In many ways, the legal side of functional medicine can feel like the Wild West—uncertain, unregulated, and full of risks. The reality is, we all want to have our practices legally buttoned up, but navigating the legal landscape can feel overwhelming—and expensive. What Scott Rattigan, creator of Functional Lawyer, shares in this episode is a real game-changer. He not only breaks down the complexities of the legal side of things but also offers real solutions for us—solutions that can make sure we're covered without the stress and uncertainty that often comes with it. Whether you're just starting out or growing your established practice, you're going to get actionable insights on how to avoid common legal pitfalls, protect your practice, and actually move forward with confidence. It’s a topic that’s been an unmet need for so long, and I'm so excited to bring this to you. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

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Download 5 Essential Legal Documents for Every Functional or Integrative Medicine Practice: https://www.functionallawyer.com/resource-downloads

GUEST DETAILS

Scott Rattigan, JD

Founder: Functional Lawyer: https://www.functionallawyer.com/kf

Co-founder: Origins Incubator - https://www.originsincubator.com/

The Junto Podcast Playlist: https://fxmedlaw.com/junto-youtube

LinkedIn: https://www.linkedin.com/in/scott-rattigan/

Email: info@functionallawyer.com

Phone: 941-229-0928

Scott Rattigan, JD, is the founder of Functional Lawyer, offering flat-rate legal solutions to help practitioners protect their licenses and grow their businesses. Inspired by helping his wife build her functional medicine practice, Scott provides high-quality legal support for health coaches, doctors, and more. He’s an attorney, internationally recognized speaker, host of The Junto with Scott Rattigan, bestselling author of The Practice of Telemedicine, and co-founder of the practice success software ReveliaDx.

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Functional Lawyer: https://www.functionallawyer.com/kf

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7 months ago

1 hour 25 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Why You’re Aging Faster Than You Think & How to Slow It

I’ve been looking forward to sharing this conversation with you because it’s one I’m truly passionate about. Today, we’re diving into the DunedinPACE epigenetic clock with one of its creators, the brilliant Dan Belsky. It’s a tool I use regularly with my patients, and one that’s transforming how we approach aging and interventions. While this show is a bit more technical than usual, the science is fascinating, and the real-world applications are incredibly valuable. This isn’t just about theory—it’s about practical insights that can change how we measure aging and track the effectiveness of the treatments we offer. Stick with us, and you’ll walk away with actionable knowledge that can make a difference in your practice. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Daniel W Belsky, PhD

Website: www.belskylab.com

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7 months ago

1 hour 11 minutes 12 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

What New Research Says About Cartilage Regeneration and Joint Longevity

What if a human trial of over 1200 patients showed improved mobility and reduced pain in osteoarthritis (OA) patients using a natural combination of boswellia and celery seed extract? What if a second follow-up randomized, placebo-controlled human trial found that within 90 days, this same combination increased OA patients' ability to perform a walk test by over 50%, reduced markers of cartilage degeneration by half and increased markers of cartilage regeneration by half. This is what the research team at Calroy Health Sciences have discovered, putting a tremendous amount of work and financing into studying the effects of the uniquely-developed Cartigenix-HP. Not only that, increased joint space at the end of the trial was clearly visible via radiography, and 90% of the intervention group did not need any "rescue" pharmaceutical medication at the end of the 90 day period (compared with only 20% of the placebo group) and this effect was sustained beyond the end of the trial. I have to say, I am impressed and excited about the potential for this new product to help my patients and I am thinking about other applications like OA prevention and osteoporosis! Listen in to find out more. ~ DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Kiran Krishnan, Microbiologist

Kiran Krishnan is a research microbiologist and a health and wellness expert who aims to make complex information understandable to all. He has founded a number of successful health and supplement companies over the last 20 years including co-founding and leading Microbiome Labs, the preeminent, microbiome therapeutics focused brand among healthcare professionals. He is currently a co-founder and partner in 3 other companies that aim to revolutionize wellness care and an advisor to Calroy Health Sciences. He has conducted and published several research studies in scientific journals, has published chapters in scientific textbooks/references books, has global patents and is a sought after speaker on human health and the microbiome.

THANKS TO OUR SPONSOR

Go to Calroy.com/drkf for exclusive resources and discounts on Cartigenix HP.

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8 months ago

1 hour 6 minutes 18 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

The Truth About Chronic Illness: How to Reset Your Nervous System & Slow Aging

We’ve all had patients struggling with chronic conditions like long COVID, fibromyalgia, Lyme disease, and chronic fatigue. Despite all the tools in our functional medicine toolkit, there’s still something missing. How can we truly help them? I’m excited to have Ashok Gupta back on the New Frontiers podcast to offer a new take on healing from chronic illness. He explains that many chronic diseases stem from a malfunction in the brain's threat detection system, where the body overreacts to perceived threats, triggering immune, nervous system, or mood responses, creating a vicious cycle. Ashok shares how retraining the brain and calming the nervous system can reset the body’s response to chronic stress and presents the growing body of research supporting the Gupta Program, including new subjective measurements like CRP showing its impact. What excites me most is the potential for this approach to help some of my toughest-to-treat patients. With more studies emerging, I’m increasingly hopeful this could be a game-changer. It’s a conversation you won’t want to miss! ~DrKF

Check out the show notes at https://tinyurl.com/2t55s3y3 for the full list of links and resources.

GUEST DETAILS

Ashok Gupta Email: ashokguptaprogram@gmail.com https://guptaprogram.com/

Ashok Gupta is an internationally recognized speaker, filmmaker, and health practitioner who specializes in supporting individuals with chronic illness. After overcoming ME (Chronic Fatigue Syndrome) through his own neuroplasticity research, Ashok developed the Gupta Program in 2007 to help others recover. He has published several medical papers and continues to research chronic conditions, with recent studies demonstrating the effectiveness of the Gupta Program. Ashok is dedicated to advancing holistic approaches to healing and improving outcomes for those facing chronic illness.

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8 months ago

1 hour 6 minutes 19 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Hidden Mitochondria Problems Are Accelerating Your Age & Draining Your Health

What if the key to reversing chronic disease, slowing cognitive decline, and boosting energy lies in the tiny powerhouses inside your cells—and we’ve finally found a way to protect them?

We know mitochondria power our cells, but did you know they also create oxidative stress as they generate energy? Protecting mitochondrial health is critical—but most antioxidants can't reach inside the mitochondria where protection is needed most—until now. MitoQ, a scientifically advanced, mitochondria-targeted antioxidant developed by visionary researchers in New Zealand penetrates mitochondria up to 90%, offering protection where it's needed most.

In this episode with Dr. Siobhan Mitchell, we dive into how MitoQ is transforming the way we tackle chronic disease, inflammation, and cognitive decline. From improving heart health to supporting brain function, MitoQ is changing the game. It’s something I’m using personally and recommending to most of my patients. Listen in to discover how this powerful tool can help you support your patients at the cellular level—before symptoms even appear. ~DrKF

Check out the show notes at https://tinyurl.com/2t55s3y3 for the full list of links and resources.

GUEST DETAILS

Dr Siobhan Mitchell, PhD., MitoQ Chief Scientific Officer Email: smitchell@mitoq.com

Holding a PhD in neuroscience from SUNY Albany, Siobhan Mitchell has also completed a post-doctoral fellowship on brain aging at the University of Washington. She has over 15 years of clinical research experience, seven patents on mood and cognitive food products, and has authored over 50 papers on aging, brain health, nutrition, metabolic health and more. With a personal passion for brain aging research, Siobhan has worked on metabolic and skin health, appetite, sports physiology and of cellular health –which she now focuses on as the Chief Scientific Officer for research-backed cellular health company, MitoQ – creators of the world’s first mitochondria-targeted antioxidant.

THANKS TO OUR SPONSOR

MitoQ: https://www.mitoQ.com/partner CustomerService@mitoq.com

OFFER FOR NEW FRONTIERS LISTENERS

Practitioners - Sign up to become a MitoQ Partner, access wholesale rates, and Unlock Cellular Health for your Patients by going to https://www.mitoq.com/partner

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Show more...

9 months ago

1 hour 12 minutes 21 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

p-Tau 217: The Breakthrough Biomarker Revolutionizing Early Alzheimer’s Detection
Join me for a fascinating conversation around an exciting breakthrough in dementia detection that’s offering real hope for early intervention. Dr. Hans Frykman, Chief Scientific Officer at Neurocode Laboratories, is here to share groundbreaking insights into cutting-edge biomarkers that can identify pathology associated with Alzheimer's disease before symptoms even appear. What’s even more fascinating is how these same tools are revealing neuroinflammation caused by infections, including COVID, Lyme disease, and mold exposure—issues that are incredibly relevant in functional medicine today. The assays Dr. Frykman and his team have developed, and continue to research, are transforming the way we think about diagnosing and addressing neurodegeneration. We’re talking about a potential game-changer that allows us to intervene earlier, reverse damage, and ultimately improve the trajectory of these conditions. This is an extraordinary time in science and medicine, and the work we’re discussing today is at the forefront of it all. Don’t miss out on how this could reshape your practice. ~DrKF

Check out the show notes at https://tinyurl.com/2t55s3y3 for the full list of links and resources.

GUEST DETAILS
Dr. Hans Frykman, MD PhD FRCPC hfrykman@neurocode.com
Hans Frykman MD, Ph.D., FRCPC is the founder, CEO, and medical director of BC Neuroimmunology Lab located in the UBC hospital on the University of BC campus in Vancouver BC. He is the medical director for Lykke Lab a genetics laboratory also on the University of BC campus. Also, he is the CSO for Neurocode Lab Inc. in Bellingham WA, a high-complexity, specialty lab focused on neuroimmunology and biomarkers in neurodegeneration. Dr. Frykman has a clinical faculty position at the University of British Columbia, Faculty of Medicine, Division of Neurology.
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Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz
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9 months ago
1 hour 7 minutes 49 seconds

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Exosomes are becoming one of the most talked-about tools in regenerative medicine, but not all exosomes are created equal. In this episode of New Frontiers, Dr. Kara Fitzgerald talks with Alisa Lask, CEO of Plated Skin, about the science behind platelet-derived exosomes and why their signaling pathways matter for repair, renewal, and changes in skin appearance.
We explore how discoveries in cardiology led to this technology, what early clinical studies are showing, and why source and preparation are critical when evaluating any exosome-based approach. A clear, grounded look at a fast-moving field for clinicians who want to understand what’s real, what’s emerging, and what deserves attention next.
Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/
GUEST DETAILS Alisa Lask is the CEO of Rion Aesthetics, where she is driving innovation in regenerative aesthetics with platelet-derived exosomes and leading research in areas like hair restoration and skin appearance. She also oversees (plated)™ Skin Science, a medical-grade exosome skincare line distributed through aesthetic providers.
Alisa previously held senior roles at Galderma, Allergan, Zimmer-Biomet, and Eli Lilly, and she serves on the Board of Directors for CollPlant. She holds an MBA from the University of Michigan and is also a nationally competitive show-jumping equestrian involved in dog rescue initiatives.
THANKS TO OUR SPONSOR
(plated)™ Skin Science: http://platedskinscience.com/
Plated Skin Science translates the discovery of Dr. Atta Behfar, M.D., Ph.D., Director of Mayo Clinic’s Van Cleve Cardiac Regenerative Medicine Program into the first shelf-stable skincare line using regenerative, platelet-derived exosomes. These aren’t generic exosomes; they’re a specific class shown in peer-reviewed trials to regenerate skin's appearance by improving the look of wrinkles, pigmentation, luminosity, and overall skin quality. It’s an elegant approach to visible signs of skin aging, recognized by Time as a Best Invention of 2024 and now used in more than 2,000 medical practices. Learn more at http://platedskinscience.com/
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