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Endo Untangled
Dr Alecia Macrow GP with Cherie Noble EP
15 episodes
1 week ago
Unravels the complexities of endometriosis and persistent pelvic pain – one conversation at a time. Join Dr Alecia Macrow, GP and founder of Thrive Family Practice, and Exercise Physiologist Cherie Noble, as they explore the tangled threads of pelvic pain with compassion, curiosity, and clinical insight. From hormones to hypermobility, trauma to treatment gaps, Endo Untangled dives into the real-life experiences and science behind one of the most misunderstood conditions in women’s health. We talk to experts, share stories, and challenge outdated thinking.
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Health & Fitness
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All content for Endo Untangled is the property of Dr Alecia Macrow GP with Cherie Noble EP and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Unravels the complexities of endometriosis and persistent pelvic pain – one conversation at a time. Join Dr Alecia Macrow, GP and founder of Thrive Family Practice, and Exercise Physiologist Cherie Noble, as they explore the tangled threads of pelvic pain with compassion, curiosity, and clinical insight. From hormones to hypermobility, trauma to treatment gaps, Endo Untangled dives into the real-life experiences and science behind one of the most misunderstood conditions in women’s health. We talk to experts, share stories, and challenge outdated thinking.
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Health & Fitness
Episodes (15/15)
Endo Untangled
When Period Pain Stops Kids Going to School - PPEP Talk with Michelle Nielsen: Endo Untangled Summer

In this Fast and Curious episode from the Pelvic Pain Foundation annual seminar, Michelle Nielsen talks about PPEP Talk, the Periods, Pain and Endometriosis Program.

PPEP Talk is an engaging, medically accurate education session for secondary students that helps young people understand what normal period pain looks like, when pain is concerning, what endometriosis is, and practical strategies to manage pain and seek help. It has been delivered to more than 65,000 students across Australia, with data showing that before PPEP Talk many students did not know what endometriosis was but that knowledge rises dramatically after the session, empowering young people with new understanding.

A high proportion of students report severe period pain and many miss school or work because of it, and there are marked differences in impact between regional, rural and metropolitan students.

Michelle discusses what schools and clinicians find valuable about the program, how it supports students in sport and study, and why early education like this matters for long term health and wellbeing.


Find out more about the PPEP talk program:

https://www.pelvicpain.org.au/ppep-talk-schools-program/

PPEP talk Menstrual Education Video:

https://www.youtube.com/watch?v=EF2K7luhGPk

QENDO app:

https://www.qendo.org.au/the-app

PIPPA tool:

https://www.canberrahealthservices.act.gov.au/services-and-clinics/services/canberra-endometriosis-centre/period-impact-and-pain-assessment-pippa/period-impact-and-pain-assessment-pippa-online-screening-tool

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2 weeks ago
14 minutes 14 seconds

Endo Untangled
Ep 12: Endometriosis and fertility; expert insights with Professor Louise Hull

TW: Fertility is discussed here, and we know this can be a painful subject for those with endo and pelvic pain. If this raises concerns for you, give yourself permission to skip this episode.

In this episode, we talk with Professor Louise Hull, a reproductive medicine specialist and world-leading researcher in endometriosis. Louise shares her story, from IVF training at Cambridge to leading national research and policy here in Australia. She gives one of the clearest explanations of how endo causes pain, inflammation and damage, and how this links to fertility.

We explore:

  • Prof Louise's take on how endo actually causes pain
  • The link between endo and infertility, and what patients should know early
  • When surgery helps fertility, and when it might reduce ovarian reserve
  • Egg and embryo freezing, and how to make that decision
  • Impact of hormone treatments on long term fertility
  • What GPs and other health professionals often get wrong about fertility and endo
  • The myths, the gaps, and what Louise wishes every patient understood

This is a grounded and compassionate conversation that will be useful for patients, GPs, and anyone supporting someone with endo.

Louise is also the lead investigator behind EndoZone, a national digital platform that gives patients and clinicians access to evidence-based, user-friendly information about endometriosis. Check out this excellent resource at www.endozone.com.au

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4 weeks ago
1 hour 9 minutes 8 seconds

Endo Untangled
Ep 11: Endo, endometrioma , ovarian cysts and a new gold standard with A/Prof Mathew Leonardi

In the second episode of our endometriosis imaging arc, we sit down with world class excision surgeon and leading pelvic sonologist Dr Matthew Leonardi to explore how high quality pelvic ultrasound transforms the way we understand endometriosis. Matthew explains how advanced ultrasound maps disease in three dimensions, reveals deep lesions that laparoscopy can miss, and helps patients build a clearer, more accurate story of what is happening in their pelvis.

We break down the full spectrum of ovarian cysts, from follicular and haemorrhagic cysts to dermoids and endometrioma, and unpack why the term “complex cyst” causes unnecessary fear and needs to disappear. Matthew also shares how recognising an endometrioma is often just the start, and how detailed ultrasound guides safer, more precise surgical planning.

We finish with his interdisciplinary Endometriosis 360 model, where imaging, pelvic physio, dietetics and psychology work together to support better long term endo care.

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1 month ago
59 minutes 24 seconds

Endo Untangled
Ep 10: Yes, you can see endo on ultrasound with the right technique. We examine high quality endo scans, anatomy and the sonographic confessional, with Ali Deslandes

Join us on Endo Untangled as Dr Alecia Macrow and Cherie Noble sit down with Alison Deslandes – clinical academic sonographer, endometriosis researcher and founder of Astute Ultrasound Education – to explore how advanced imaging is reshaping the diagnostic landscape for people living with endometriosis and pelvic pain.

In this episode you’ll hear:

  • Why a “normal” scan doesn’t always mean everything’s fine – and what to ask if the standard ultrasound isn’t giving you answers

    • How specialised transvaginal ultrasound protocols and the “sliding sign” technique help detect deep-disease and posterior pouch involvement that many imaging pathways miss.
    • Who the hell is Douglas and why is he in my pelvis? and other anatomy including where to find the uterosacal ligaments and where exactly is the peritoneum in the pelvis.
    • The real-world impact of Australia’s new Medicare rebate for endometriosis imaging, and why access still hinges on finding ultrasound services with the right training and expertise.

    • The emerging role of artificial intelligence in sonographer training – and what that could mean for future scans, reporting and surgical planning. Alison Deslandes

    Whether you’re a healthcare practitioner committed to improving care, a patient seeking better diagnostic clarity, or a partner navigating the care journey together – this episode offers practical insight, nuance and hope. Tune in, open your mind and equip yourself with the language and questions to get the ultrasound conversations you deserve.


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    1 month ago
    55 minutes 52 seconds

    Endo Untangled
    Ep 09: The science of pain, and what *actually* helps pelvic pain, with scientist Dr Millie Mardon

    In this episode of Endo Untangled, Dr Millie Mardon PhD shares how her long trips from Port Augusta to Adelaide as a teenager shaped her work in pain science. She explains how understanding what pain really is can help us change it, slowly but surely.


    We talk about where pain discussions go wrong, how what we think, feel and see can shift the way pain shows up, and why personal stories matter in research and recovery.


    This one will change how you think about pain.


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    2 months ago
    51 minutes 47 seconds

    Endo Untangled
    Ep 08: A Pain in the Bum! When pelvic pain hits the bowels, with Dr Chris Gillespie

    In Episode 08, we dive deep (no pun intended) with specialist colorectal and pelvic floor surgeon Dr. Chris Gillespie as he lifts the lid on everything your bowels don’t want you to ask. From the anatomy and reflexes behind a good poop, to what’s going on when your colonoscopy is “normal” but symptoms persist, we cover it all. We unravel the role of anorectal manometry, bust common myths (do laxatives really make your bowel “lazy”?), and get his go-to strategies for managing bowel dysfunction in real life. Whether you’re a clinician, patient, or just poop-curious — this one’s for you.


    Tune in, flush away the stigma, and get the inside track on what your gut’s been trying to tell you.

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    2 months ago
    1 hour 4 minutes 20 seconds

    Endo Untangled
    Ep 07: Lightning vag? Random stabs? Pelvic muscles and why so painful: Alycia Scannell & Caz Berry

    Titled Pelvic Health Physios Alycia Scannell and Carolyn Berry explain how overprotective pelvic floor muscles can tighten and guard, leading to stabby pains, bladder urgency, bowel changes, deep pelvic aching, tailbone pain, or painful sex.


    They share how treatment goes far beyond exercises. It is about calming the nervous system, teaching the body safety again, and helping people reconnect with their pelvic floor through awareness, breathing, and gentle retraining.

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    2 months ago
    59 minutes 26 seconds

    Endo Untangled
    Ep 06: Unpacking the pain and fatigue double whammy with expert pain physio Sophie Sheppard

    In this episode of Endo Untangled, physiotherapist Sophie Sheppard shares her lived experience of chronic fatigue as a teenager and later discovering she is autistic and ADHD. We unpack the science of persistent pain and how it reverberates through the nervous, endocrine and immune systems (the NEI ensemble), and explore how understanding the whole-system impact changes care. Sophie explains how these insights shape her work as a pain-titled physiotherapist, helping people untangle complex pain and reclaim their lives.


    Whether you are living with persistent pain, supporting someone who is, or working as a health professional, this episode offers understanding, compassion, and practical insights.

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    3 months ago
    58 minutes 6 seconds

    Endo Untangled
    Endo Untangled, Fast and Curious Ep 01: The Brain-Uterus Axis with A/Prof Susan Evans

    Welcome to the first of our Endo Untangled mini ep series, Fast and Curious.

    We met with A/Prof Susan Evans at the recent Pelvic Pain Foundation of Australia Annual Practitioner Seminar in Brisbane, to pick her brains on:


    - the relationship with the uterus, brain, nervous, and immune system

    - Dr Evans' work with Alyra Biotech in the development of some novel therapies for endometriosis and pelvic pain, tapping into the neuro-immune activation that underpins the pain and whole-body symptoms that are associated with endometriosis

    - How this new therapy came about, on the grounds of Tokyo University


    If you're interested in finding out more about Dr Susan's trial, please visit www.alyrabiotech.com.

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    3 months ago
    11 minutes 6 seconds

    Endo Untangled
    Ep 05: Standing Up to POTS with Dr Marie-Claire Seeley (Part 2)

    From tests to treatment, here’s how to take your next steps with POTS.

    In Part 2 of our conversation, Dr Marie-Claire Seeley takes us deeper into the journey of postural orthostatic tachycardia syndrome (POTS). We explore what investigations can actually help, practical management strategies that make a difference, and how to start feeling better day to day. Whether you’re newly diagnosed or years into navigating POTS, this episode offers clarity, hope, and real-world tools you can use.

    If you find this episode helpful, share it with someone who might need it and follow Endo Untangled for more conversations that bring insight and support.

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    3 months ago
    40 minutes 9 seconds

    Endo Untangled
    Ep 04: Standing Up to POTS: Dr Marie Claire Seeley’s POTS story, pt 1

    Unwell in Central Asia. Dismissed as “just anxiety.” Four kids, nursing shifts, and a fight to be believed. Today Dr Marie-Claire Seeley is CEO of the Australian POTS Foundation, using her PhD and lived experience to change care for people with POTS.

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    4 months ago
    57 minutes 34 seconds

    Endo Untangled
    Ep 03: Bridging the Gap: Why Endo Conversations Go Off Track – and How to Get Them Back, with Gynaecologist and Pain Physician A/Professor Susan Evans and Women's Health GP Dr Carmel Reynolds.

    Why does endo care feel like a tug-of-war?

    Pill pushback • stabbing pains • surgery debates.


    Why do so many endo appointments leave patients feeling unheard and doctors feeling stuck? In this episode, GP Dr Alecia Macrow and EP Cherie Noble sit down with Prof Susan Evans and Dr Carmel Reynolds to unpack why care can feel like control, why “they just want to put me on the pill” is such a common refrain in forums, and how sharp “ovary pains” aren’t always what they seem.

    We talk about:

    • ​The disconnect across the desk and how to rebuild partnership
    • ​Why hormonal treatments are offered so often (and how to talk about them without shutting down choice)
    • ​Stabbing pains, ovary myths, and what’s really going on
    • ​Surgery: when it helps, when it doesn’t, and why it’s not the whole story

    This is a constructive, honest conversation for patients, clinicians, and anyone wanting to better navigate endo care.

    A/Prof Evans discusses her current clinical trial with Alyra Biotech, you can find more information here:

    https://alyrabiotech.com/clinical-trials/

    as well as her new book "When Periods Hurt – A guide to periods, pain and endometriosis for Teens" available here:https://www.pelvicpain.org.au/product/whenperiodshurt/

    We also discussed some of the great resources available at the Pelvic Pain Foundation, which are available hereLhttps://www.pelvicpain.org.au/find-support/download/


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    4 months ago
    59 minutes 6 seconds

    Endo Untangled
    Ep 02: The pelvic pain super-syndrome with Dr Sneha Wadhwani

    Ep 2: The Pelvic Pain “Super Syndrome” with Dr Sneha Wadhwani


    Why the fatigue? Why the headaches? Why the lightning arse?!


    In this episode, we dive into the messy overlap of gut issues, pelvic floor dysfunction, heavy periods, and crushing fatigue – and why these symptoms so often show up together. Dr Sneha Wadhwani joins us to explore what we’re calling the Pelvic Pain “Super Syndrome” and how recognising these patterns can completely shift how we approach care.


    We talk about:

    • ​How pelvic pain can be driven – and kept going – by multiple factors across the body and brain
    • ​The difference between endometriosis as a disease and pelvic pain as a condition
    • ​Why understanding the links between gut, nerves, hormones, and the pelvic floor is so important
    • ​What patients and clinicians can do with this knowledge to get better outcomes


    If you’ve ever felt like your symptoms don’t fit neatly into one box, this episode will help you see the bigger picture.


    Check out Dr Sne’s podcast, “Everything from A to V” on Spotify here https://open.spotify.com/episode/1snC82WBvSrfWgtmi1v0m8?si=9SZVDO_zRr6QVbKV70t4pA

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    5 months ago
    46 minutes 16 seconds

    Endo Untangled
    Ep 01: Introducing the Tangle

    Exercise Physiologist Cherie Noble and Endo GP Dr Alecia Macrow talk through the 'why' of Endo Untangled, their personal stories, and what they're most looking forward to in the podcast.

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    5 months ago
    13 minutes 53 seconds

    Endo Untangled
    Endo Untangled - season preview

    Full series dropping soon

    Show more...
    6 months ago
    1 minute 2 seconds

    Endo Untangled
    Unravels the complexities of endometriosis and persistent pelvic pain – one conversation at a time. Join Dr Alecia Macrow, GP and founder of Thrive Family Practice, and Exercise Physiologist Cherie Noble, as they explore the tangled threads of pelvic pain with compassion, curiosity, and clinical insight. From hormones to hypermobility, trauma to treatment gaps, Endo Untangled dives into the real-life experiences and science behind one of the most misunderstood conditions in women’s health. We talk to experts, share stories, and challenge outdated thinking.