First Rounders

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First Rounders

Nature Biotechnology

61 episodes

11 months ago

Nature Biotechnology's First Rounders podcast is a series of conversations with founders, financers and developers from biotech's past, present and future.

Hosted on Acast. See acast.com/privacy for more information.

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Natural Sciences

All content for First Rounders is the property of Nature Biotechnology and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.

Nature Biotechnology's First Rounders podcast is a series of conversations with founders, financers and developers from biotech's past, present and future.

Hosted on Acast. See acast.com/privacy for more information.

Show more...

Natural Sciences

Episodes (20/61)

First Rounders

Brady Huggett signs off.

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3 years ago

4 minutes 28 seconds

First Rounders

Jay Keasling is a professor in the College of Chemistry at the University of California at Berkeley, where he runs the Keasling lab. He’s also the CEO of the Joint BioEnergy Institute, and has been involved in several startups. His conversation with Nature Biotechnology covers growing up on the family farm in Nebraska, how Genentech led him into biotech, and the future of biofuels.

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3 years ago

1 hour 11 minutes 46 seconds

First Rounders

Ingmar Hoerr is a co-founder and former CEO of CureVac. His conversation with Nature Biotechnology covers his initial discovery with RNA while in his PhD program, the struggle to find venture financing for CureVac, and how a brain aneurysm changed his view on life.

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3 years ago

1 hour 3 minutes 22 seconds

First Rounders

Lita Nelsen is the former long-time director of the Technology Licensing Office at the Massachusetts Institute of Technology. Her talk with Nature Biotechnology covers her father’s life designing television antennas, what drove her to the chemical engineering program at MIT, and the ingredients required to create an entrepreneurial environment on campus (and beyond).

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4 years ago

52 minutes 17 seconds

First Rounders

Hope Lies in Dreams Chapter 1

Stan Crooke is born ⬩ A tenuous existence ⬩ Life with his mother ⬩ The Tech Corner ⬩ Arsenal Tech High School ⬩ Nancy ⬩ Hoodlum ways ⬩ Off to Purdue

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4 years ago

33 minutes 47 seconds

First Rounders

Anthony Atala is the director of the Institute for Regenerative Medicine at Wake Forest University. He is also a co-founder of Precise Bio. His conversation with Nature Biotechnology covers implanting the first tissue-engineered bladder into a patient, Wake Forest’s plans for fostering entrepreneurship, and how he was coerced into a research career by a mentor.

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4 years ago

1 hour 6 minutes 5 seconds

First Rounders

Nancy Simonian is president and CEO of Syros Pharmaceuticals. Her conversation with Nature Biotechnology covers going against the advice of her mentor to take a job at Biogen; the long, winding path to approval for the multiple myeloma drug Velcade; and assisting her father in the operating room as a girl.

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4 years ago

1 hour 7 minutes 45 seconds

First Rounders

Carl June is a co-founder of Tmunity Therapeutics, and a professor in immunotherapy at the University of Pennsylvania, where he also runs the June Lab. His conversation with Nature Biotechnology includes how a boyhood fractured arm led him to his first scientific experiment, his years of service with the Navy, and his groundbreaking work with CAR T-cells.

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4 years ago

1 hour 5 minutes 11 seconds

First Rounders

Craig Mello is co-founder of Atalanta Therapeutics and a professor at the University of Massachusetts Medical School, where he runs the Mello Lab. He is also a Nobel Laureate. His conversation with Nature Biotechnology covers the lure of conspiracy theorists, the state of RNA therapeutics, and getting that call from the Nobel committee.

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4 years ago

1 hour 12 minutes 2 seconds

First Rounders

Neil Kumar is a co-founder and CEO of BridgeBio Pharma. He discussed with Nature Biotechnology his youth in the Midwest, the founding principles behind BridgeBio, and understanding where your strengths lie.

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4 years ago

1 hour 1 minute 4 seconds

First Rounders

Grace Colón is president and CEO of InCarda Therapeutics. Her conversation with Nature Biotechnology covers growing up in San Juan, Puerto Rico; her love of musical theater; and how grad school at MIT guided her toward a career in entrepreneurship.

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5 years ago

1 hour 3 minutes 39 seconds

First Rounders

Tillman Gerngross

Tillman Gerngross is the CEO and co-founder of Adimab, and a professor of bioengineering at Dartmouth College. His conversation with Nature Biotechnology covers his years at GlycoFi, the nature of problem solving in entrepreneurship, and Adimab’s paper last year challenging the work of MIT researcher Ram Sasisekharan.

Editor's note: Ram Sasisekharan has since been cleared of these charges. Please see https://www.statnews.com/2023/06/14/ram-sasisekharan-mit-vindicated-fraud-investigation/ and https://www.wsj.com/articles/mit-drug-researcher-cleared-in-research-probe-3d050624?utm_source=headtopics&utm_medium=news&utm_campaign=2023-06-15 for more information.

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5 years ago

1 hour 12 minutes

First Rounders

Noubar Afeyan is the founder and CEO of Flagship Pioneering. His conversation with Nature Biotechnology covers his family fleeing the Lebanese Civil War when he was a boy, how a chance encounter at a scientific meeting opened his mind to entrepreneurism, and why immigrants (and entrepreneurs) benefit from having a “paranoid optimist” mindset.

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5 years ago

1 hour 7 minutes 46 seconds

First Rounders

Katrine Bosley is former CEO of Editas Medicines and Avila Therapeutics. She discusses growing up in Ohio, her first job in biotech (as an administrative assistant) and why her five years at CRISPR company Editas felt more like 1,000. This episode is part of Nature Biotechnology's focus issue on translating the CRISPR technology.

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5 years ago

1 hour 8 minutes 37 seconds

First Rounders

Ted Love is the president and CEO of Global Blood Therapeutics. In his conversation with Nature Biotechnology, he discusses why his time at Haverford College was transformative, why he views Global Blood Therapeutics as a social justice company, and what might be gained from the “racial catharsis” happening in America after the police killing of George Floyd.

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5 years ago

1 hour 22 minutes 22 seconds

First Rounders

Alexis Borisy is CEO and Chairman of EQRx, and a long-time biotech builder with Third Rock Ventures. His conversation with Nature Biotechnology covers growing up as a “faculty brat” in Wisconsin, dropping out of his PhD program at Harvard and why, even as an investor, biotech cannot be all about the money.

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5 years ago

1 hour 5 minutes 39 seconds

First Rounders

Bonus: Jeremy Levin

A conversation with Jeremy Levin, chairman of the Biotechnology Innovation Organization and CEO of Ovid Therapeutics, about industry versus government responses to covid19, the split within biotech on how to address charges of high prices, and why the biopharma industry is so disliked.

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5 years ago

46 minutes 23 seconds

First Rounders

Bassil Dahiyat is co-founder, president and CEO of Xencor. His conversation with Nature Biotechnology covers his parents emigrating from Jordan, how Xencor has survived (and changed) over the past 22 years, and when it’s necessary for a CEO to speak out.

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5 years ago

1 hour 3 minutes 40 seconds

First Rounders

Forum: Schneeberger on Clavien

Senior Editor Irene Jarchum talks to Stefan Schneeberger about the significance of a recent Nature Biotechnology paper describing a sophisticated perfusion machine to keep human livers alive for a week. The work was carried out by Pierre-Alain Clavien and colleagues from ETH Zurich. Read the paper here.

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5 years ago

22 minutes 20 seconds

First Rounders

Greg Verdine is a professor at Harvard University, and CEO and president of FogPharma and LifeMine Therapeutics. He is co-founder of more than 10 companies. His talk with Nature Biotechnology covers growing up in the Pine Barrens of New Jersey, the importance of excelling in the lab versus the classroom, and drugging the undruggable.

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6 years ago

1 hour 13 minutes 23 seconds