Get the latest on mankind's mission to find a vaccine or cure for HIV/Aids as Dr Michelle Moorhouse chats with Prof. Penny Moore, Reader and NRF/DST South African Research Chair of Virus Host Dynamics at Wits University and NICD.

How safe, reliable and accurate is HIV self-testing? Well, joining Dr Moorhouse to answer this is Mohammed Majam from Wits RHI and Jonathan Gunthorp, the Executive Director of the Southern African AIDS Trust.

Are you in the right mindset for 2016? Kamini Pather thinks we could all use a little guidance, she is joined by a psychologist who will give both western and eastern advice. They look at what healthy New Year's resolutions are and tackle depression and overall mental health, ensuring you're geared up to kick 2016's A$$. Donovan Goliath joins to reveal the dark side of comedians and his own experience with depression.

What should you do in the first few seconds of an emergency? Netcare 911 Clinical Head, Richard Mulder, tells you this and has some first aid for beginners that he wants to share. Then, creative director Conn Bertish, tells of how he instinctively viewed his life-threatening cancer diagnosis as a challenge and what solutions he found that helped to save his life.

Leading expert in stress management, Dr Arien van der Merwe, believes that stress is essential to 21st century survival. She shares practical tools and techniques to manage and take an integrated approach to stress. Then, any parent with a child battling addiction will tell you how difficult and invasive regular drug testing can be, Russell Hutton talks about the future of non-invasive drug testing kits, joining him is a mother who knows first hand the difficulties of traditional testing methods.

It's an unavoidable part of a woman's life, with an estimation 25 million women every year entering menopause. Dr Sibongile Nomganga tells you what's happening to your body, what symptoms to expect, how your menstrual cycle will change, as well as how to cope with hot flushes and night sweats.

With World AIDS Day being commemorated, Dr Sindi talks about living positively with HIV. She is joined by Ntimbwe Mpamba, who was born with HIV and is dedicated to helping other youths in his position. Ntimbwe is the oldest person in Africa living with HIV who was born HIV+.

Dr Sindi tells you how you can support Pulmonary Hypertension Month and explains just what this disease does to its patients. Then we hear from renowned physiotherapist-turned-entrepreneur Gary Arenson, who will gives tips on improving pain and discomfort associated with bad posture and working in an office environment.

With the international community recently commemorating World Diabetes Day, Jonathan Sinclair stands in for Dr Sindi and speaks to Lize van Dorsten and Kerry Kalweit from Youth With Diabetes, a non-profit organisation that empowers children, teens and young adults with Type 1 Diabetes, with support, knowledge, skills and confidence to live happy and healthy lives. Both Lize and Kerry have grown up with Type 1 Diabetes and are using their experience to helps others.

World Hospice and Palliative Care Day has taken place and to commemorate this occasion Dr Sindi talks to CEO of Hospice Palliative Care Associate Dr Liz Gwyther who provides the facts surrounding the future of palliative care in our country and worldwide.

Dr Sindi introduces you to the first ever clinically tested sexual stimulant to hit the market. Applied externally, it increases sensitivity and blood flow, creating a more intense and pleasurable experience for women. She talks to Dr Eve who's a couple and sex therapist about this new product.

The doc's guest is Dr Claire Jamieson, who created a natural skincare range out of necessity, as her own daughter suffered from bad eczema, and she was unable to find any product that worked without irritating her skin. Sindi also chats to Nombulelo Ngamlana, who has been practising as a Pharmacist for 12 years.

A cure for Type 1 Diabetes. Sound too good to be true? Think again! Dr Eli Lewis is a world-renowned expert on autoimmune disease, breaking new ground in seeking a cure for Type 1 Diabetes. His research focuses on improving the transplantation therapy of insulin producing cells in diabetic patients. Dr Lewis and his team have discovered a common, easily accessible drug that can protect transplanted cells, reversing diabetes and restoring glucose control in diabetic patients. Dr Lewis joins Dr Sindi today and tells more about his groundbreaking research.

215 million women worldwide would like to use a contraceptive method. However, in developing countries not all women have access to modern contraceptive methods and many are unsure of their options. Dr Sibongile from Bayer's Women Health demystifies the myths surrounding contraception and advises women on which contraceptive methods could best suit them. Men, don't think this does not affect you, empower yourself with knowledge!

Radiofrequency and ultrasound treatments are quite the trend due to being non-invasive and non-painful, while still delivering phenomenal results in terms of skin rejuvenation, tightening of the face and body fat reduction. Medical Doctor in Aesthetics Dr Catherine Davies talks about vaginal rejuvenation and other new and exciting, non-invasive cosmetic procedures.

Sleep Professor Alison Bentley talks about using biology to sleep better and why we all can't sleep solidly for 8 hours, she also debunks some "sleep myths" with Dr Sindi.

Dr Riaz Motara is the pioneer behind the The Women's Heart Clinic. The clinic focuses on preventative cardiology and a holistic approach to heart health. Dr Motara joins Dr Sindi to talk about 'KardioFit' and heart health in general. Then Dr Sindi chats to the organiser of the 'Organic Life Fair'. This fair allows one to take the first step towards a natural holistic and healthy way of living.

September is Heart Awareness Month, dedicated to raising awareness about cardiovascular disease in South Africa, culminating with World Heart Day on the 29th of September. Dr Sindi speaks with the Heart and Stroke Foundation about the importance of awareness, regular check-ups, early detection and support.

Medical aesthetics is a growing trend that focuses on improving cosmetic appearance through the treatment of various conditions. Dr Sindi speaks with Dr Fatima Bhabha, owner of the female only run practice, Beauty & Curves. Dr Bhabha specialises in treating African and Asian skin types, however that doesn't mean she doesn't know a thing or two about Caucasian skin. A member of the ASLMS -American Society for Lazer Medicine and Surgery AAAM- American Academy of Aesthetic Medicine SACD - South African Association of Cosmedic doctors. I also have my diploma in Aesthetic medicine from AAAM and will be chairing numerous sessions at the upcoming COSMEDICA 2015. I have brought one of the latest crazes in aesthetic medicine around the world to the shores of S.A., the VENUS CONCEPT range. We have been distributing this range for the last 3 years and in june 2015 had a launch at the hyatt to hand over distribution. I am a woman only run practice

Dietitian Thando Msomi, talks with Dr Sindi about aspects of healthy eating that can improve your quality of life. She also discusses her everyday job.