68: Metformin Blunts Vascular Insulin Sensitivity After Exercise

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Listen, Learn, Adapt

Anthony Novello

76 episodes

3 days ago

One research article dissected in plain, clear language... no opinions, just evidence. Diving into the world of health & wellness, physical medicine & rehab, and pain. We will help you understand the evidence and apply it to real life. Whether you're an athlete, a healthcare provider, someone who enjoys staying informed, or just getting started with health and wellness, this podcast makes research easy to follow, digest, and use! Dr. Anthony Novello, PT, DPT https://www.instagram.com/anthonynovello.dpt/

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68: Metformin Blunts Vascular Insulin Sensitivity After Exercise

Listen, Learn, Adapt

39 minutes 6 seconds

4 weeks ago

68: Metformin Blunts Vascular Insulin Sensitivity After Exercise

This episode does a deep dive into a study that investigated the combined effects of the drug metformin and various exercise training intensities on vascular health. The research utilized a double-blind, placebo-controlled trial involving adults at risk for Metabolic Syndrome, dividing participants into groups receiving either low-intensity exercise (LoEx) or high-intensity exercise (HiEx), each with either metformin (Met) or a placebo (PL).

Malin SK, Heiston EM, Battillo DJ, Ragland TJ, Gow AJ, Shapses SA, Shah AM, Patrie JT, Barrett EJ. Metformin Blunts Vascular Insulin Sensitivity After Exercise Training in Adults at Risk for Metabolic Syndrome. J Clin Endocrinol Metab. 2025. doi:10.1210/clinem/dgaf551.

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