Welcome back to the Peptides for Women podcast!
In today's episode, weโre talking about three major benefits you can get from using a GLP-1s beyond weight loss. By the end of this episode, youโll see that GLP-1s can help regulate your blood sugar, calm inflammation, and support your liver so you feel better day-to-day.
In this episode, I break down:
BENEFIT #1: Better Glucose & Insulin Regulation
How GLP-1s slow gastric emptying, which means steadier blood sugar after meals
Why fewer post-meal spikes = fewer energy crashes (and fewer cravings)
The impact on insulin sensitivity and long-term metabolic health
BENEFIT #2: Lower Inflammation
The surprising connection between GLP-1s and reduced systemic inflammation
My personal story: how tirzepatide helped relieve my hip pain and plantar fasciitis
What the research is showing about inflammation markers improving on GLP-1 therapy
BENEFIT #3: Improved Liver Health
How GLP-1s can lower liver enzymes like ALT, AST, and GGT
Why better liver function = less bloating, more energy, and smoother digestion
The link between fatty liver, perimenopause, and insulin resistance
๐ Resources:
1.โ Effects of semaglutide on beta cell function and glycaemic control in participants with type 2 diabetes: a randomised, double-blind, placebo-controlled trial โ https://pubmed.ncbi.nlm.nih.gov/28526920/ ย
2. Changes in Glucose Metabolism and Glycemic Status With Once-Weekly Subcutaneous Semaglutide 2.4 mg Among Participants With Prediabetes in the STEP Program โ https://pubmed.ncbi.nlm.nih.gov/35724304/ ย
3. Weight Loss-Independent Effect of Liraglutide on Insulin Sensitivity in Individuals With Obesity and Prediabetes โ https://pubmed.ncbi.nlm.nih.gov/37874653/ ย
4. Impact of semaglutide on high-sensitivity C-reactive protein: exploratory patient-level analyses of SUSTAIN and PIONEER randomized clinical trials โ https://pubmed.ncbi.nlm.nih.gov/36056351/ ย
5. Effects of once-weekly semaglutide 2.4 mg on C-reactive protein in adults with overweight or obesity (STEP 1, 2, and 3): Exploratory analyses of three randomised, double-blind, placebo-controlled, phase 3 trials โ https://pubmed.ncbi.nlm.nih.gov/36467859/ ย
6. GLP-1 alleviates NLRP3 inflammasome-dependent inflammation in perivascular adipose tissue by inhibiting the NF-ฮบB signalling pathway โ https://pubmed.ncbi.nlm.nih.gov/33641439/ ย
7. A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis โ https://pubmed.ncbi.nlm.nih.gov/33185364/ ย
8. Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study โ https://pubmed.ncbi.nlm.nih.gov/26608256/ ย
9. Tirzepatide for Metabolic Dysfunction-Associated Steatohepatitis with Liver Fibrosis โ https://pubmed.ncbi.nlm.nih.gov/38856224/ ย
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