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Biochemistry | Gluconeogenesis and Glycogen Metabolism
PodBites
21 minutes
3 weeks ago
Biochemistry | Gluconeogenesis and Glycogen Metabolism
🍐 In this episode of PodBites, Mashour and Faisal walk you through gluconeogenesis and glycogen metabolism — the metabolic pathways that quietly keep your brain alive between meals.
🎙️ Tune in to explore:
Why glucose is so tightly protected by the body
How gluconeogenesis kicks in during fasting (and where its energy comes from)
The key bypass steps that make it not just glycolysis in reverse
High-yield cycles like the Cori cycle and glucose–alanine cycle
How glycogen is built, stored, and rapidly broken down
The different roles of liver vs muscle glycogen
Hormonal control by insulin, glucagon, and epinephrine
Classic clinical ties like metformin, McArdle disease, and Pompe disease
🌟 A clear, story-driven breakdown that turns metabolic pathways from something you memorize into something that actually makes sense.