Listen as Drs. Mike Wilkes and Mark Ebell discuss a new systematic review that found some conditions for which skeletal muscle relaxants are effective, and others for which they are not.

Join Drs. Ebell and Wilkes as they discuss this weeks POEM. It addresses the question of whether beta-blockers should be continued indefinitely after a myocardial infarction.

Join Drs. Mike Wilkes and Mark Ebell as they discuss the use of e-cigarettes to help people quit smoking.

Join Drs. Mike Wilkes and Mark Ebell as they discuss digital behavioral therapy to treat symptoms of fibromyalgia:

Gendreau RM, McCracken LM, Williams DA, et al. Self-guided digital behavioural therapy versus active control for fibromyalgia (PROSPER-FM): A phase 3, multicentre, randomised controlled trial. Lancet 2024;404(10450):364-374. 

Join Drs. Mike Wilkes and Mark Ebell as they discuss a new randomized trial of probiotics for UTI:

Gupta V, Mastromarino P, Garg R. Effectiveness of prophylactic oral and/or vaginal probiotic supplementation in the prevention of recurrent urinary tract infections: A randomized, double-blind, placebo-controlled trial. Clin Infect Dis 2024;78(5):1154-1161.

This week, Drs Wilkes and Ebell discuss a new meta-analysis of the CV benefit of SGLT-2 inhibitors, which is less dramatic than you might think.

This week primary care Drs. Wilkes and Ebell talk about the long term harms of multiple UTIs in children.

This week Mike and Mark discuss a new meta-analysis summarizing all of the data on the benefits of antibiotics for kids.

Join primary care physicians Drs. Mike Wilkes and Mark Ebell as they discuss the comparative death rates for patients hospitalized with influenza, RSV and COVID-19