Standard Uranium Vice President of Exploration Sean Hillacre joined Steve Darling from Proactive to share that the company has received exploration permits for its Corvo Uranium Project, which is currently under a three-year earn-in option agreement with Aventis Energy. The approval clears the way for an ambitious field program that will include high-resolution geophysical surveys and the project’s first-ever modern drill campaign, scheduled to begin in January 2026. Under the newly issued 18-month permit, the company plans to complete an extensive ground gravity survey over the property. The program will utilize a tight 50-metre by 200-metre grid and will cover more than 29 kilometres of conductive strike length across the project. More than 5,000 individual gravity stations will be measured as part of the survey. Hillacre explained that this work is designed to identify density anomalies that could represent hydrothermal alteration systems associated with uranium-fertile electromagnetic conductor trends, significantly refining drill targeting across the project. Following completion of the gravity survey, Standard Uranium plans to launch a skid-assisted diamond drilling program totaling approximately 3,000 metres during the winter 2026 field season. This campaign will mark the first drilling on the Corvo Project in more than four decades, representing a major milestone in the advancement of the property. Hillacre told Proactive that the drill program will focus on several high-priority targets, including the Manhattan Showing, which has never been drilled, along with multiple newly identified radioactive occurrences discovered through recent exploration work. The company believes these targets offer strong potential for uranium mineralization and could unlock significant new discoveries at Corvo. With permits now in hand and work programs defined, Standard Uranium is positioned to systematically advance the Corvo Project through modern exploration for the first time in a generation, as it seeks to build value through new uranium discoveries in a strengthening nuclear fuel market. #proactiveinvestors #standarduraniumltd #tsxv #stnd #otcqb #sttdf #mining #uranium #corvoproject #UraniumExploration #AthabascaBasin #DavidsonRiver #MiningInnovation #Geophysics #AmbientNoiseTomography #ResourceInvesting #FleetSpace #UraniumDiscovery #MiningNews

Starpharma CEO Cheryl Maley joined Steve Darling from Proactive to discuss the company’s recent momentum in oncology development and strategic partnerships, underscoring growing commercial and clinical interest in its proprietary dendrimer-based drug delivery platform. Maley explained that Starpharma’s technology enables more efficient and targeted drug delivery and has demonstrated significant benefits in oncology. The dendrimer platform is designed to improve the therapeutic performance of medicines while reducing side effects and toxicity, and can be applied across a wide range of molecules, from small-molecule drugs to complex antibodies. She confirmed that Starpharma signed two major agreements in 2025. The first was an exclusive licensing deal with Genentech, valued at up to 860 million Australian dollars plus royalties, focused on a specific and undisclosed area of oncology. The second was a research collaboration with Radiopharm Theranostics that includes an option for exclusivity. In parallel with its partnering activity, Starpharma continues to advance its internal development programs, particularly in radiotherapy. Maley said the company is targeting the entry of these assets into clinical trials in 2026. Starpharma also maintains a strategic relationship with private equity group Medicxi through a joint venture structure. On the commercial front, Maley highlighted the company’s plans to grow revenue from its two registered products, VIRALEZE and VivaGel, which are now available in approximately 35 countries. She added that Starpharma currently has three Phase 2 assets in development, with two of those programs actively targeted for licensing. #proaxctiveinvestors #starpharma #asx #spl #otc #sphry #OncologyInnovation #DrugDeliveryTech #BiotechNews #CherylMaley #GenentechPartnership #Radiopharm #VIRALEZE #VivaGel #DendrimerTechnology #PharmaPartnerships #ASXBiotech #ClinicalTrials #BiopharmaUpdates #Medicxi

MustGrow Biologics Corp Chief Executive Officer Corey Giasson joined Steve Darling from Proactive to discuss the company’s financial results for the three months ended September 30, 2025, highlighting a meaningful step forward in revenue generation and margin performance. During the quarter, MustGrow reported revenue of $0.8 million, marking a significant improvement from the same period last year, when the company recorded no revenue. Gross profit for the quarter totaled $180,555, resulting in a gross margin of 22.9%, up from 20.9% in the second quarter of 2025. Giasson attributed the sequential improvement in margins to a stronger mix of higher-margin product sales through the company’s Canadian sales and distribution division, NexusBioAg. From a balance sheet perspective, MustGrow ended the quarter with $3.3 million in cash and cash equivalents, along with $1.9 million in inventory on hand. Giasson noted that the company remains disciplined in its capital allocation strategy, continuing to focus on investments that support revenue growth across both its NexusBioAg Canadian operations and its TerraSante biofertility product sales in the United States. Giasson also emphasized the seasonal nature of the company’s business, pointing out that the third calendar quarter is typically the lowest revenue “shoulder season” for Canadian agriculture, as farmers are more focused on harvesting activities rather than purchasing crop input products. Despite this seasonal slowdown, he said the company continues to make progress in strengthening its commercial platform and positioning itself for improved sales performance in future quarters. #proactiveinvestors #mustgrowbiologicscorp #tsxv #mgro #otcqb #mgrof #mustardseed #TerraSante #Biofertility #Agriculture #BiologicalFarming #RegenerativeAg #SustainableFarming #NexusBioAg #AgTech #CropProtection #FarmingInnovation #CanadianFarming #adjuvantsplus

Bitwise Asset Management European head Bradley Duke talked with Proactive's Stephen Gunnion about the recent decline in Bitcoin's price and what it could mean for investors. Duke noted that while some view the fall from over $110,000 to $87,000 in November as a "disaster," others see it as a chance to accumulate at discounted levels. “It really is a sort of a Black Friday discount price for people who want to get involved,” he said. He explained that the downturn was triggered by a tweet from former President Donald Trump announcing a sharp tariff hike on China. Since crypto markets trade around the clock, Bitcoin bore the immediate brunt of the selloff while traditional markets were closed. This sparked a wave of profit-taking by long-term holders and panic selling by short-term investors, further accelerating the price decline. Despite this, Duke said institutional demand remains evident. Flows into Bitcoin ETPs continue, although somewhat tempered, and some large holders—or "whales"—have been buying the dip. The company has also engaged with investors who previously felt they had missed the opportunity to enter the market and now see more attractive entry points. Looking ahead, Duke pointed to seasonal patterns that could support Bitcoin in December. He noted historical spikes in Bitcoin ETP flows towards year-end, particularly from both European and US investors, which could help lift the price as the year closes. Visit Proactive’s YouTube channel for more videos like this, and don’t forget to give the video a like, subscribe to the channel, and enable notifications for future content. #Bitcoin #Cryptocurrency #BTC #Bitwise #BradleyDuke #CryptoInvesting #BitcoinPrice #CryptoMarkets #BitcoinETP #InstitutionalCrypto #ProactiveInvestors

Amerant Investments chief investment officer Baylor Lancaster-Samuel talked with Proactive's Stephen Gunnion about the launch and strategy behind the Amerant Latin American Debt UCITS ETF (RNTA). Lancaster-Samuel explained that RNTA was created to meet the needs of Latin American clients who want exposure to local corporates without the difficulties of constructing diversified portfolios themselves. “You need sort of five to six million dollars in order to get enough diversity,” he noted, citing bond denomination sizes as a barrier for many investors. The ETF takes an active investment approach, targeting high-performing corporate bonds from the largest and most stable economies in Latin America, including Brazil, Mexico, Colombia, and Chile. The strategy avoids distressed issuers, with zero exposure to Venezuela and caution around defaults such as Argentina. Lancaster-Samuel emphasised that the ETF is US dollar-denominated, reducing currency risk for clients already exposed to local currencies. He described the portfolio as concentrated (40–60 names), highlighting the opportunity in Latin America where “corporates trade with additional spread for the same amount of leverage.” The ETF is designed for income-focused investors, with a quarterly distribution and a focus on carry rather than capital appreciation. He added that RNTA could appeal to both retail and institutional investors seeking targeted emerging market exposure. For more interviews and insights, head over to Proactive’s YouTube channel. Don’t forget to like the video, subscribe to our channel, and turn on notifications for the latest updates. #LatinAmericaETF #FixedIncome #EmergingMarkets #CorporateBonds #RNTA #AmerantInvestments #ETFInvesting #ETF #IncomeInvesting #ActiveManagement #USDollarBonds

Valereum PLC (AQSE:VLRM) CEO Gary Cottle talked with Proactive's Stephen Gunnion about the company’s newly announced $200 million royalty and streaming financing agreement with Quorum Global Photonics (QGP), a fund based in the Cayman Islands specialising in tokenisation and resource-based assets. Cottle explained that the deal involves a token swap rather than traditional debt financing, providing Valereum with a quarterly annuity stream of over $2 million. “We actually receive the coupon, not pay the coupon,” he said, describing the instrument as a perpetual call certificate that delivers consistent capital inflow to help grow and operate the business. He noted the partnership is expected to be long-term and strategic, with QGP potentially taking up to 49.9% ownership in Valereum within a year. This, he said, would lead to shareholder dilution but is part of a broader vision to bring in strategic investors aligned with Valereum’s focus on tokenisation and AI in the streaming space. Cottle also revealed that Valereum is preparing for a US exchange listing, targeting Nasdaq or NYSE, with a timeline of six to twelve months, depending on revenue developments and acquisitions. Several potential acquisitions are in progress to build out the revenue base required for that listing. Visit Proactive's YouTube channel for more videos, and don't forget to give the video a like, subscribe to the channel and enable notifications for future content. #Valereum #GaryCottle #QGPDeal #RoyaltyStreaming #Tokenisation #BlockchainFinance #AIinFinance #StrategicInvestment #NasdaqListing #EquityFinance #ProactiveInvestors #DigitalAssets #USListing #CryptoFinance

New Era Energy & Digital CEO Will Gray joined Steve Darling from Proactive to announce a major expansion milestone for the company’s flagship digital infrastructure development. Texas Critical Data Centers (TCDC)—the company’s 50/50 joint venture with Sharon AI, Inc.—has finalized a definitive purchase and sale agreement to acquire an additional 203 contiguous acres near Odessa, Texas. This brings the total development footprint to 438 acres, significantly boosting the site’s capacity to support a multi-phase, multi-gigawatt AI and high-performance computing (HPC) campus designed to scale well beyond 1 gigawatt. Gray explained that this enlarged footprint provides the long-term scalability required as global demand for AI compute accelerates and enterprises pursue increasingly GPU-intensive workloads. He added that the company is already in active commercial discussions with several prospective tenants seeking large-scale, power-dense environments with future-proof expansion capabilities—criteria that the expanded TCDC site is uniquely positioned to meet. The site also offers multiple strategic advantages that strengthen project economics and reduce development friction. Its proximity to high-capacity fiber routes, major intrastate natural-gas transmission lines, and existing CO₂ pipeline corridors provides opportunities for efficient power integration, advanced cooling solutions, and optionality for future carbon capture, utilization, and storage (CCUS) systems. These infrastructure synergies are expected to lower interconnection complexity, shorten development timelines, and enable TCDC to deploy sustainable, high-performance digital infrastructure at scale. Gray also detailed the company’s ongoing geotechnical and engineering work, including drilling and civil studies essential for large-scale data center construction. He emphasized that New Era is shifting from a powered land model toward a powered shell development strategy—prioritizing long-term recurring revenue streams rather than short-term land sales. This strategic pivot reflects the company’s broader vision to operate as a vertically integrated digital infrastructure developer. As part of that effort, TCDC is currently in exclusive discussions on a potential triple net lease with a major anchor tenant. While Gray noted that a formal announcement is unlikely in the fourth quarter, he said the company anticipates finalizing the agreement in early Q1. Operational milestones remain on schedule for 2026, including Phase 1 construction and initial tenant occupancy. To support execution, Gray said the company plans to make several C-suite hires and expand its development and engineering teams as planning progresses. #proactiveinvestors #neweraheliuminc #nasdaq #nuai #oil #gas #perimianbasin #HeliumProduction #NaturalGas #DataCenters #AIInfrastructure #PecosSlope #VerticalIntegration #EnergyMarkets #PermianBasin #Semiconductors #PowerGeneration #ProactiveInvestors

Power Metallic Mines CEO Terry Lynch joined Steve Darling from Proactive to provide an update on the company’s ongoing drilling activities and its planned listing on the New York Stock Exchange. Lynch noted that although the listing process experienced a brief delay due to the U.S. government shutdown, the company now expects to debut in New York in January. “They’ll start the new year off with a bang in New York,” he said. At the company’s recent annual general meeting, shareholders raised concerns about the recent decline in share price. Lynch attributed the drop to broader market conditions and a fund sell-off, despite strong operational news. He emphasized that the company’s fundamentals remain robust and that investor interest has strengthened in recent weeks. Power Metallic Mines is currently executing a large-scale 100,000-metre drill program with five rigs active and additional rigs—potentially a sixth or seventh—expected to join. Assay results from this summer’s drilling campaign are anticipated shortly after American Thanksgiving. The company continues to expand its resource base across four key targets and advance toward future development milestones. “We’re bullish on all of them,” Lynch said, underscoring confidence in the projects currently being drilled. #proactiveinvestors #powernickelinc #tsxv #pnpn #otcqb #cmetf #nickel #mining #invest #investing #PowerMetallicMines #MiningIndustry #PolymetallicExploration #Copper #Nickel #TSXVenture #TerryLynch #ProactiveInvestors #InstitutionalInvestment #Gold #Silver

Aftermath Silver CEO Ralph Rushton joined Steve Darling from Proactive to confirm that the company has completed the final payment required to secure full ownership of the Berenguela silver-copper-manganese project—nearly two years ahead of the original November 2026 deadline. Rushton explained that this early payment brought meaningful benefits. EMX Royalty Corporation agreed to reduce the amount of the final payment by US$100,000 and, importantly, waived Aftermath’s obligation to complete and file a Pre-Feasibility Study (PFS) by November 23, 2025, a requirement previously set out in the amended Berenguela Acquisition Agreement. With this final payment now made, Aftermath Silver has satisfied all financial commitments under the acquisition deal. Rushton noted that the company is now working closely with SSR to finalize the formal transfer of ownership of the Berenguela project. Looking ahead, Aftermath will launch a full, comprehensive PFS for Berenguela. The study will evaluate a development plan centered on producing silver, copper, and manganese—three commodities in strong demand across industrial supply chains and emerging technologies. Rushton said this work represents a major step forward in positioning Berenguela as a significant future source of these critical metals. #proactiveinvestors #aftermathsilverltd #tsxv #aag #otcqx #aagff #mining #SilverMining, #BerenguelaProject, #Mining #Silver #Copper #Manganese #Peru #DrillingResults #BatteryMetals #ResourceModel #Investing

Tooru PLC (LSE:RGO) CEO Scott Livingston talked with Proactive's Stephen Gunnion about the company's strategy for growth through its portfolio of health and wellness consumer brands. Livingston began by outlining the core brands under Tooru, including Juvela, a gluten-free range sold via prescription; OAF, its mass-market gluten-free line launched in Tesco; Pulsin, a long-established protein bar and supplement brand; and Purely, a plantain crisps label. The company also operates Market Rocket, a tech division supporting direct-to-consumer growth. “We think that we can grow these existing brands dramatically,” Livingston said, citing strong demand for clean-label, functional foods. He also noted the strength of OAF’s launch and its traction with retailers and consumers. Livingston confirmed Tooru is EBITDA positive at the operating company level and is seeing the effects of investments made into product development and brand turnaround. The company is prioritising organic growth, but remains open to strategic acquisitions that align with existing operations or offer synergy on the production side. Tooru is positioning itself within a growing health and wellness sector, with Livingston stating, “Even low-income area teenagers would read what's on the back of a product,” reflecting a wider consumer shift towards transparency and healthier choices. For more interviews like this, visit Proactive's YouTube channel. Don’t forget to like this video, subscribe, and turn on notifications for future updates. #TooruPLC #HealthAndWellness #GlutenFree #OAF #Pulsin #ConsumerBrands #OrganicGrowth #CeliacFriendly #NutritionTrends #EBITDA #FoodInnovation #ScottLivingston #ProactiveInvestors

Rainbow Rare Earths Ltd (LSE:RBW, OTC:RBWRF) CEO George Bennett talked with Proactive's Stephen Gunnion about a major milestone in the company's development of the Phalaborwa rare earths project in South Africa. Bennett outlined how Rainbow’s decision to switch from ion chromatography to solvent extraction (SX) as the separation method for rare earth elements significantly reduces risk. He said, “This is a significant de-risking step for Rainbow because now we're using tried, proven and tested technology.” The company engaged ANSTO, the Australian Nuclear Science and Technology Organisation, to confirm the viability of its solvent extraction circuits, which are expected to achieve the necessary 99.5% purity levels for both NdPr and the SEG+ groups. Bennett also discussed the implications of soaring yttrium prices, which have risen dramatically from $6/kg to over $220/kg in some contracts. He said Rainbow has now attracted interest from one of the largest aerospace and jet engine manufacturers globally for yttrium offtake. According to Bennett, the SEG+ group could generate approximately $160 million in revenue at 70% payability, compared to previous estimates of $80 million, marking a significant boost to EBITDA. Bennett concluded by confirming that key technical milestones have been achieved, enabling a more defined DFS timeline targeting mid-2026. For more updates, visit Proactive's YouTube channel. Don't forget to like the video, subscribe to the channel, and enable notifications for future content. #RareEarths #RainbowRareEarths #Yttrium #PhalaborwaProject #GeorgeBennett #NdPr #ANSTO #SolventExtraction #CriticalMinerals #ProactiveInvestors #MiningNews #StrategicMetals #GreenEnergyMetals #TechMetals #RareEarthSeparation

Caledonia mining CEO Mark Learmonth joined Steve Darling from Proactive to discuss the company’s decision to formally proceed with the development of the Bilboes gold project in Zimbabwe, following the completion of a comprehensive feasibility study. The long-awaited study confirmed the project’s compelling economics and positioned Bilboes as one of the most significant future gold developments in the region. Learmonth highlighted that the project delivers an NPV of more than $580 million at an 8% discount rate, based on a gold price assumption of $2,548 per ounce. The internal rate of return exceeds 32%, supported by a competitive all-in sustaining cost of $1,061 per ounce. “That clearly means that it’s a very high-margin operation with a very quick payback period,” Learmonth told Proactive. The feasibility study recommends developing Bilboes as a single-phase, large-scale operation, with peak capital expenditure estimated at $484 million, plus roughly $100 million in financing-related costs. According to Learmonth, the single-phase plan generates superior returns compared to a phased development approach, benefiting from economies of scale and stronger overall project metrics. Caledonia expects to fund the build primarily through a combination of non-recourse senior debt and internal equity from Blanket Mine, which is set to support the financing through a newly arranged three-year gold hedge at a minimum strike price of $3,500 per ounce. This hedge is anticipated to generate approximately $200 million in cash flow to underpin project construction. Looking ahead, Learmonth outlined a timeline that sees construction beginning in the second half of 2026, with first gold production targeted for late 2028, contingent on finalising debt agreements. The company also plans to deliver further exploration updates from Blanket and Motapa in early 2026, adding additional potential growth catalysts. Beyond its economic strength, Bilboes represents a major milestone for Zimbabwe’s mining sector. Learmonth described it as a “marquee project” with the potential to meaningfully boost national gold production, attract new investment, and reinforce the country’s profile as a destination for world-class gold development. #proactiveinvestors #aim #cmcl #nyseamerican #cmcl #caledoniamining #GoldInvesting #MiningStocks #ZimbabweMining #BilboesProject #GoldProduction #FeasibilityStudy #MiningDevelopment #JuniorMining #MiningEconomics #GoldPrice #ResourceInvestment

Cordiant Digital Infrastructure Management chairman Steven Marshall and Cordiant Digital Infrastructure Ltd (LSE:CORD) CFO Andrew Ewe talked with Proactive's Stephen Gunnion about the company’s continued financial performance and strategic progress, with net asset value (NAV) surpassing £1 billion. Marshall said the NAV growth reflects the strong demand across digital infrastructure, as "demand for more and more capacity across the plumbing of the internet" continues to drive performance. He highlighted the strength of Cordiant's buy, build and grow strategy and underscored the value being delivered through hands-on management of portfolio companies. Ewe detailed the financial resilience underpinning the results, noting a 2.175 pence per share interim dividend, which is "50% of the target set earlier in the year." He also pointed to a dividend coverage ratio of 1.7 times and over £200 million in undrawn debt and cash, supporting continued capital expenditure and acquisitions. The acquisition of BT Ireland and construction plans for the Prague Gateway data centre are among key growth catalysts. Ewe noted that "this could be a significant driver of the NAV" as development progresses. Both executives acknowledged the current discount to NAV, with Marshall stating he and colleagues had bought more shares, confident in the long-term value of the platform. Visit Proactive’s YouTube channel for more interviews and market insights. Don’t forget to like the video, subscribe to the channel, and enable notifications for future content. #CordiantDigital #InfrastructureInvestment #NAVGrowth #DigitalInfrastructure #AIandData #PragueGateway #BTIreland #DividendStocks #CapitalGrowth #ProactiveInvestors

Tonix Pharmaceuticals Holdings CEO Dr. Seth Lederman joined Steve Darling from Proactive to announce a major milestone for the company and for patients: TONMYA is now commercially available by prescription at pharmacies across the United States. TONMYA is a first-in-class, non-opioid analgesic designed specifically for adults with fibromyalgia and is taken once nightly at bedtime. Dr. Lederman told Proactive that this marks a transformative moment for the estimated 10 million Americans living with fibromyalgia, a chronic condition characterized by widespread pain, sleep disturbance, fatigue, and impaired quality of life. TONMYA offers a novel therapeutic option that directly targets the condition’s core, debilitating symptom—chronic pain—while also showing positive effects on associated symptoms. The commercial launch follows a substantial clinical development program, including the recently published RESILIENT Phase 3 trial in Pain Medicine. The study evaluated TONMYA on primary endpoints measuring pain reduction and secondary endpoints assessing overall patient-reported improvement, symptom severity, sleep quality, functional impact, and fatigue. The published findings reinforce TONMYA’s role as a meaningful new option in a field where therapeutic advances have been limited. Regulatory approval incorporated efficacy and safety results from two double-blind, randomized, placebo-controlled Phase 3 trials involving nearly 1,000 patients. In both studies, TONMYA demonstrated a statistically significant reduction in daily pain scores at 14 weeks, meeting the primary endpoint. A higher proportion of patients receiving TONMYA also achieved clinically meaningful pain improvement after three months compared with placebo, underscoring its real-world therapeutic relevance. With its U.S. pharmacy availability now in place, TONMYA becomes a first-in-class, non-opioid option designed to address the multi-dimensional burden of fibromyalgia—and represents a significant step forward for patients seeking relief and improved daily functioning. #proactiveinvestors #tonixpharmaceuticalsholdingcorp #nasdaq #tnxp #Biotech #Tnx-1500 #transplant #kidneydisease #massachusettsgeneralhospital #massgeneral #VaccineDevelopment #ClinicalTrials #PharmaceuticalNews #MedicalResearch #WHO #GlobalHealth #InfectiousDiseases #Biopharma #ProactiveInvestors

Trust Stamp EVP John Bridge joined Steve Darling from Proactive to outline the company’s newly announced patent-protected framework for embedding links to a biometrically validated, cryptographic chain of provenance directly into stablecoins. The update comes as global regulators intensify scrutiny on the misuse of stablecoins for illicit finance. According to recent insights from the Financial Action Task Force (FATF), stablecoins have become one of the most commonly used virtual assets by bad actors — including North Korean cybercriminals, terrorist financiers, and drug trafficking networks — with most on-chain illicit activity now concentrated in stablecoin transactions. Bridge explained that Trust Stamp’s USPTO Patent #11,681,787 captures the company’s strategy to serve as a critical infrastructure provider where distributed digital identity and digital asset issuance converge. The patent covers a system for validating ownership of cryptographic asset contracts using irreversibly transformed identity tokens. This technology enables every unit of a stablecoin to be cryptographically linked to a tokenized, non-reversible representation of its owner’s identity — without exposing any personally identifiable information on-chain. The result is a privacy-preserving, biometrically anchored chain of provenance that supports embedded ownership authentication. Bridge highlighted that the framework is designed to meet emerging regulatory expectations, offering quantum-resistant security while enabling compliant, transparent, and privacy-first issuance of digital assets in a rapidly evolving global regulatory environment. #proactiveinvestors #truststamp #nasdaq #idai #IdentityTech #DigitalIdentity #Fintech #GhanaID #SouthKoreaStartup #AsiaExpansion #KStartupChallenge #FinancialServices #Biometrics #TechExpansion #ProactiveInvestors #AndrewGowasack #wallet #TSI3 wallet #biometrics #DigitalIdentity #CryptoWallet #BiometricWallet #StableIT2 #DeFiSecurity #KYC #CryptoRecovery #LostCryptoKeys #Stablecoin #BlockchainTechnology #Web3

AtaiBeckley NV CEO Dr Srinivas Rao joined Steve Darling from Proactive to discuss the company’s official launch following the completion of the merger between Atai Life Sciences and Beckley Psytech, forming a new clinical-stage biopharmaceutical company focused on developing transformative treatments for mental health disorders. Rao said the combined company, now known as AtaiBeckley, brings together complementary expertise, proprietary technologies, and a robust clinical pipeline aimed at addressing treatment-resistant depression (TRD) and other mental health conditions. AtaiBeckley’s lead program, BPL-003, a short-acting psychedelic compound, has received Breakthrough Therapy Designation from the U.S. Food and Drug Administration (FDA) for TRD. The company expects to meet with the FDA in the coming months to finalize Phase 3 trial plans, with pivotal studies anticipated to begin in Q2 2026. The company also reported positive topline results from the open-label extension (OLE) of its Phase 2b clinical trial of BPL-003 in TRD patients. A 12 mg dose administered eight weeks after an initial dose (0.3 mg, 8 mg, or 12 mg) produced rapid, robust, and sustained antidepressant effects lasting up to eight weeks. The Phase 2b trial consisted of an eight-week, quadruple-masked, dose-finding study followed by an eight-week OLE phase. Of the 126 patients who completed the core study, 107 entered the OLE. Patients who initially received 0.3 mg recorded a mean reduction in MADRS score of 14 points by Day 57.Those who received 8 mg or 12 mg demonstrated a mean reduction of 19 points, with a 63% responder rate and a 48% remission rate at Day 57. The safety and tolerability profile of BPL-003 in the OLE remained consistent with prior studies and comparable to other compounds within the psychedelic class. Beyond BPL-003, AtaiBeckley’s pipeline includes VLS-01 (DMT buccal film) – in a Phase 2 trial for treatment-resistant depression, EMP-01 (R-MDMA) – in a Phase 2a trial for social anxiety disorder and a portfolio of preclinical 5-HT2A receptor agonists, including non-hallucinogenic neuroplastogens Rao said the newly merged entity is strategically positioned to become a leader in next-generation neuropsychiatric innovation, leveraging scientific depth and clinical momentum to bring novel treatments to patients with few or no existing options. #proactiveinvestors #ataibeckley #nasdaq #atai #clinicaltrial #bpl003 #depression #AtaiBeckley #BPL003 #PsychedelicTherapy #ClinicalTrials #MentalHealthInnovation #Phase2Results #5MeODMT #BiotechNews #DrugDevelopment #ProactiveInvestors

Northstar Gold Corp CEO Brian Fowler Joined Steve Darling from Proactive to reveal that the company has signed a Master Project Agreement with DIGITAL – Canada’s Global Innovation Cluster for digital technologies – alongside Novamera Inc. and Micon International Limited. The collaboration forms part of a broader initiative aimed at supporting data-driven, digital mining solutions for Northstar’s Cam Copper Surgical Mining Project in Ontario. Fowler explained that the agreement builds on an existing Definitive Surgical Mining Services Agreement between Northstar and Novamera, under which Novamera will deploy its fully integrated precision-mining system at Cam Copper. Over a 31-month pilot phase, the company plans to extract roughly 120,000 tonnes of high-grade copper material using advanced real-time downhole imaging, robotic drilling technology and immediate backfilling to keep environmental disturbance to a minimum. Novamera’s “Surgical Mining” method is designed to dramatically improve efficiency and reduce environmental impact by eliminating blasting, reducing waste rock generation and employing a closed-loop water circuit that results in virtually no water discharge. The reduced surface footprint and simplified operational footprint may enable a smoother permitting pathway, faster development timelines and lower overall project costs compared with conventional mining approaches. Under the strategic agreement, Northstar and Novamera will continue due diligence and implementation planning in the coming months. As part of the commercial structure, Novamera will earn a 5% revenue share from production at the Cam Copper Project. The partnership represents a significant step toward modernizing the project with cutting-edge digital and precision-mining technologies aimed at unlocking value while minimizing environmental impact. #proactiveinvestors #northstargoldcorp #cse #nsg #MiningNews #GoldDiscovery #CopperExploration #MillerProperty #KirklandLake #Investing #Gold #Copper #ProactiveInvestors #novamera #CamCopper #MiningInnovation #CopperMining #Novamera #DigitalSupercluster #SurgicalMining #MiningTechnology #HighGradeCopper #MiningCanada #ResourceDevelopment #ExplorationMining #MiningFinance

First Phosphate Corp. CEO John Passalacqua joined Steve Darling from Proactive to share that the company the company has closed another tranche of its non-brokered private placement, raising $3.5 million. This brings the total raised since June 2022 to roughly $43.6 million across 10 management-led financings. Passalacqua said the proceeds support First Phosphate’s goal of establishing a fully integrated, North American lithium iron phosphate (LFP) battery materials supply chain, targeting markets such as energy storage, data centers, robotics, mobility, and national security. The company continues to advance its high-purity Bégin-Lamarche phosphate project in Saguenay–Lac-Saint-Jean, Quebec — a rare igneous phosphate resource known for low impurities and strong suitability for LFP battery production. #proactiveinvestors #firstphosphatecorp #cse #phos #otcqx #frspf #frspf #phosphate #CriticalMinerals #BatteryMaterials #LFPCathode #FirstPhosphate #CanadaMining #GreenEnergy #SupplyChain #QuebecMining #EVBatteries #dod

Stuhini Exploration CEO Meredith Eades joined Steve Darling from Proactive to announce a significant new development at the company’s 100%-owned Ruby Creek Project near Atlin, British Columbia. Fieldwork from the 2025 exploration season has led to the identification of a potential new copper-gold porphyry system, marking a major addition to the project’s expanding portfolio of high-impact targets. Eades reported that geological teams uncovered a 400-metre-wide, discontinuous exposure of feldspar-phyric porphyry in the Ruffner area, which returned a series of high-grade copper and gold values. Eleven grab samples collected from outcrop and talus returned assays exceeding 0.5% copper, with grades reaching as high as 8.1% Cu. Gold assays were equally compelling, including 13.0 g/t Au from outcrop and 36.8 g/t Au from talus float material. The newly identified target lies approximately 3.6 kilometres from the company’s flagship Ruby Creek molybdenum deposit, further demonstrating the district-scale potential of the 29,734-hectare land package. Eades noted that the discovery underscores the strength of Stuhini’s emerging multi-metal exploration pipeline, which includes copper, gold, silver, and molybdenum prospects across the property. To build on this momentum, Stuhini has engaged Tetra Tech to complete a conceptual-level economic study of the Ruby Creek molybdenum deposit, which hosts 433 million pounds of molybdenum. This assessment leverages approximately 74,000 metres of historical drilling and a past 2006 feasibility study, with the goal of determining whether an updated Preliminary Economic Assessment (PEA) is warranted. In parallel, the company plans to advance several high-priority exploration targets, positioning Ruby Creek as a potentially significant polymetallic district with multiple pathways for development. #proactiveinvestors #stuhiniexploration #mereditheades #tsxv #stu #otcqb #stxpf #RubyCreek #CopperGold #Molybdenum #MiningInvesting #JuniorMining #ExplorationUpdate #BritishColumbiaMining #ResourceDevelopment #TetraTech

EnergyPathways PLC (AIM:EPP) CEO Ben Clube talked with Proactive's Stephen Gunnion about the company’s recent developments on the MESH project, a major initiative designated as a project of national significance in the UK. This designation enables the project to progress under a streamlined development consent order process, helping to reduce approval risks and delays. Clube explained that the company has formally submitted a gas storage license application covering both natural gas and hydrogen elements. He highlighted the project’s significant scalability, with plans for up to 60 large-scale salt caverns to store energy. “We’ve got an eye to the scalability of what we’re doing here,” Clube noted, adding that energy storage is a core challenge for the UK’s energy security and affordability. Clube also discussed the commercial potential of methane pyrolysis and hydrogen technologies being developed with KBR, Hazer, and Siemens Energy. He expressed confidence in reaching commercial scale by 2030, stating, “We’re doing it, and we’re leading the way in the UK.” On the Siemens Energy front, Clube said the current non-binding agreement is a pathway to a formal long-term contract, likely by the start of the new year. He also confirmed that multiple revenue streams—including synthetic graphite and long-duration energy storage—are under evaluation, with a clearer funding picture expected in early 2026. For more updates from EnergyPathways and other innovative energy companies, visit Proactive's YouTube channel. Don’t forget to like the video, subscribe to the channel, and turn on notifications for future content. #EnergyPathways #GasStorage #HydrogenStorage #MESHProject #BenClube #UKEnergy #EnergySecurity #HydrogenEconomy #KBR #HazerGroup #SiemensEnergy #SyntheticGraphite #LDES #NetZeroUK #ProactiveInvestors