#TheShot of #DigitalHealth 2026 episode almost didn’t happen - Jim Joyce was in the air, I was back in cold New Jersey, and Max was somewhere warm and productive (naturally). But missing it would’ve been a mistake. Max Marchione, founder of Superpower, joined me for a wide-ranging conversation on why modern healthcare is fundamentally broken - and why diagnostics, AI, data, and first-principles thinking might finally fix it. We talked about: - Growing up with chronic health issues no doctor could explain - Why “10x doctors” exist - and why most medicine can’t scale them - How AI will soon outperform humans at clinical reasoning - And what it actually takes to scale a healthcare startup without losing your soul This wasn’t a polished healthcare panel. It was a real conversation about truth, tradeoffs, and taking massive action - even when you know you’ll mess some of it up. If you’re building in health, longevity, AI, or just trying to feel better in your own body… this one’s worth your time.

What happens when a class clown from Monaghan builds one of the most quietly impactful healthtech companies in Europe - and then takes on the U.S. healthcare system? In this year-end episode of The Shot of Digital Health Therapy, we sat down with Neill Dunwoody 🇺🇦 (aka “Funwoody”), co-founder of SPRYT, to talk about resilience, rejection, healthcare absurdities, and why meeting patients where they already are matters more than building yet another app. From standing in a bin at school ➝ scaling talent at UnitedHealth Group ➝ pivoting a sports app into an AI-driven healthcare orchestration platform, Neil’s story is as honest as it is instructive. We cover no-shows, NHS, U.S. healthcare economics, founder health, Ukraine, and why humor might be one of the most underrated leadership traits. 🎧 Worth your time if you’re building, scaling, or questioning the system you’re trying to fix. Fun mentions as always: Rachel Francine, Shaun Dodimead,Optum, NHS, MediDrive, LLC 00:00 Holiday banter, community singing & year-end reflections 02:00 Meet Neil Dunwoody (“Funwoody”) 03:30 Growing up in Monaghan, sport & stand-up comedy 06:30 Humor, resilience, and rejection 08:00 Recruitment, HR, and learning to read people 15:00 Scaling talent at UnitedHealth / Optum 22:00 Blitzscaling, culture breaks & hiring mistakes 31:30 The birth of SPRYT: sports → healthcare pivot 36:00 NHS pilots, WhatsApp, and no-show economics 43:00 U.S. expansion & healthcare fragmentation 48:00 Orchestrating care beyond appointments 53:30 Ukraine, Tech Link Ukraine & purpose 56:00 Founder health, weight loss & personal reset 58:00 Closing advice to younger self

On this episode of #TheShot of #DigitalHealth therapy, Jim Joyce and I finally sat down with Amy Cosler, a dynamic healthcare leader who rose from old-school hospital sales to driving transformation across Livongo -> Teladoc Health, Lyra Health, and now Carrum Health. Amy shares stories from her early days "carrying a bag" (if you know, you know), navigating to hospital basements with paper maps, transforming a 65-year-old public company, being part of Livongo’s IPO, and leading sales in the exploding employer benefits space. She opens up about resilience, family, leadership, and why kindness and grit are not mutually exclusive. This conversation delivers deep insights for founders, sales leaders, employer-benefit innovators, and anyone navigating the rapidly evolving healthcare economy. 📉 Employers demand real savings ⏱️ Buying cycles are compressing 💸 Utilization pricing opens doors 🤝 Culture drives adoption 🏥 Value-based care delivers impact Fun mentions as always: Jim Pursley, Glen Tullman, Sean McBride, David Ebersman and many more... 00:00 – Opening banter; year-end episodes; creative side projects 03:00 – Introducing guest Amy Cosler 04:00 – Early life: oldest of four, Illinois upbringing, healthcare family roots 05:30 – First job: carrying the bag for Medaflex; 4:00 AM training rides; selling skin-prep products 09:00 – Early sales journey; winning President’s Club; joining Baxter 11:00 – Intrapreneurial experience: building a startup inside Allegiance 13:00 – Cardinal Health acquisition; leadership influences 15:00 – Transformation at Landauer; building radiation monitoring + medical physics business 20:00 – Culture shock moving from startups to legacy healthcare 23:00 – Deep dive into early clinical sales environment (maps, suits, coffee, meetings) 27:00 – Divestiture, financial success, personal reset 28:00 – Meeting her husband; triathlons; writing the first version of her book 30:00 – Enter Livongo: shifting from hospitals to employer benefits 33:00 – Livongo culture, mission focus, member empathy 35:00 – Teladoc acquisition; overnight customer communications 38:00 – Pivot to Lyra; leading sales in mental health 39:30 – Joining Carrum; value-based care for surgery, cancer, SUD 41:00 – Employer trend challenges; cost inflation; need for bold solutions 45:00 – The misconception that kindness isn’t compatible with toughness 46:00 – Lessons for entrepreneurs selling to employers 49:00 – PEPM vs utilization-based pricing 51:00 – Looking ahead; entrepreneurial future; completing her book 52:00 – Jim’s narrative future-casting question 54:00 – Amy’s emotional answer: focus on family 55:00 – Closing and thank you

This week on #TheShot of #digitalHealth Therapy, Jim Joyce and I sat down with someone who might just change how we all understand… well, everything. Because when you think “future of health tech,” your brain probably doesn’t jump to noses in petri dishes. But maybe it should. We hosted Brian Lin, a Tufts researcher and a co-founder of Cellsor, who is literally growing living smell tissue to build the world’s first biological smell "camera". Yes - a "camera" for scent. Think RGB for odors… except instead of 3 channels, humans have 400, dogs have 700, elephants have 2,000, and Jim has… well, that’s still in peer review. 😅 Some highlights: 🧠 Humans have 400 smell receptors - meaning we “smell in 400 dimensions,” far beyond what we can verbally describe. 👃 Most people begin losing smell sensitivity in their 50s–70s without realizing it. 🛡️ The same tech could detect explosives, chemical threats, or hazardous compounds at checkpoint distance. 🔬 Brian’s company uses living tissue, not electronic sensors - truly an actual biological nose. 📡 The system aims to create the world’s first universal smell-recording “camera.” 💡 Future applications span diagnostics, food science, perfumery, defense, and everyday consumer tech. The science is wild, the implications are massive, and the conversation? Pure fun. 🎧 Give it a listen - and trust me, this one will stay with you in ways you can’t quite describe… because we don’t yet have the right vocabulary for smell. Fun mentions as always: Laura Hamilton Daniel Couchman Kendall #healthcare #digitalhealth #biotech #innovation #futureofwork #AI #sensorytech 00:00 – 02:10 Thanksgiving Banter & Show Opening Eugene and Jim share Thanksgiving plans, travel updates, and open the episode. 02:10 – 03:20 Scoop of Thanks Story A heartwarming story about cancer survivors bringing ice cream to oncology staff. 03:20 – 04:25 Introducing Brian Lin Jim recounts meeting Brian at Boston Startup Week over beer and ham sandwiches. 04:25 – 06:15 How Brian Meets People (The Whiskey Method) Brian explains his tradition of bringing whiskey to conferences to meet people. 06:15 – 07:45 Brian’s Background Growing up in Reading, Massachusetts; parents immigrating from China. 07:45 – 10:20 Childhood Pyro Stories Thermite experiments, accidental bed fires, and early science curiosity. 10:20 – 12:20 Education Path Undergrad at RPI, moving to Tufts for a PhD, meeting his wife. 12:20 – 15:00 From Cancer Lab to Smell Research Why cancer signaling wasn’t a fit and how he discovered the olfaction lab. 15:00 – 17:00 The Beer That Improves Dissections A lab story about shaky hands, a Corona with lime, and perfect dissections. 17:00 – 21:00 Understanding Smell Biology Why smell matters, how neurons regenerate, and why people lose smell with age. 21:00 – 24:00 COVID and Smell Loss How COVID reprograms smell neurons, parosmia, and Brian losing smell in Scotland. 24:00 – 28:00 Smell, Culture, Memory, and Diagnosis How smell connects to emotion, depression models, and historical healing. 28:00 – 32:00 Dogs Detect Cancer; Human Nose Complexity Why electronic noses fail and how humans actually smell in 400 dimensions. 32:00 – 35:00 Growing a Living Nose in a Dish Founding CellSaur and using real biological tissue instead of sensors. 35:00 – 38:20 Applications and the Smell Camera Concept Recording smells like RGB/hex codes and connecting to perception models. 38:20 – 41:10 Business Strategy for Smell Tech Three-step pathway: R&D tools, security/defense, and medical diagnostics. 41:10 – 45:00 Market Imagination Future possibilities like airport screening, drones, and household smell libraries. 45:00 – 47:00 Fundraising as a First-Time Founder Brian shares what it’s like shifting from academia into startup fundraising. 47:00 – 50:00 Final Question and Advice Jim gives a future scenario; Brian answers with “hold your conviction.”

On this 3d long-form edition of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had the privilege of sitting down for an unforgettable deep dive with Tim Wentworth, the candid, thoughtful, fiercely grounded and recently retired CEO of Walgreens (previously CEO of Evernorth Health Services). Tim’s story reads like a masterclass in leadership and life itself - from sweeping parking lots in Rochester to leading global healthcare giants like Cigna’s Evernorth and Walgreens. Across nearly two hours (and honestly, we could’ve gone four), Tim brought raw honesty, wisdom, and humor to every story - from his early scholarship thanks to a teacher who believed in him, to leading multi-billion dollar companies but always defining what it means to lead with heart. This is not just a leadership interview - it’s a living case study in resilience, humility, and purpose. 🧠 Key Takeaways 🔥 From parking lots to the C-suite 🏢 The birth, growth, and controversy of PBMs 💊 Merck - Medco, and the spin-off that changed healthcare 💼 Crisis leadership 101 💰 Cigna, Evernorth, and the end of rebates? 🏪 Walgreens, reinvention, and going private 💡 The power of asking for help 🎯 Leadership as legacy Fun mentions as always: Shaine Borukhovich Jay Parkinson, MD, MPH Dr Jack Kreindler Roberto Ascione Mark Cuban Robert Pellegrini Glen Stettin, MD David Snow Kenny Klepper David Benshoof Klein Richard Lungen Frank Sheehy David Cordani Neal Sample Per Lofberg 00:00 — Cold open: Parking-lot beginnings & the teacher who changed Tim’s life 06:20 — Early career: Music industry, Pepsi, Mary Kay, discovering healthcare 13:40 — Joining Medco: First exposure to healthcare operations 21:10 — PBM history: Why PBMs exist, why pharma once owned them, and why that broke 31:55 — Merck → Medco spinout: Fixing the original conflict of interest 41:12 — Express Scripts: Crisis moments, lawsuits, leadership under fire 50:28 — Cigna acquisition: Building Evernorth and changing the role of services 01:02:00 — The “no more rebates” move: What it means and why it matters 01:15:45 — Why Tim came out of retirement to lead Walgreens 01:20:50 — Was he brought in to take Walgreens private? 01:29:30 — Running a 300,000-person company vs. running a PBM 01:38:40 — The future of community pharmacy & neighborhood care 01:46:10 — Startups, AI, and what founders keep getting wrong 01:54:50 — Leadership legacy & advice to his younger self

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had the pleasure of chatting with the globally minded and endlessly curious Alette Ramos Hunt, PhD, Global Director, Digital Innovation & AI for Drug Discovery at Novartis. From being a third culture kid (Danish dad, Filipino mom, born in Japan, raised in Hong Kong) to becoming one of the sharpest voices connecting biotech, digital health, and AI, Alette brings perspective that’s as international as it is insightful. We explored her fascinating path from studying proteins in Glasgow to driving AI innovation in pharma, and how she’s bridging the gap between molecules, humans, and machines. She reminded us that practical AI and game-changing AI both have a place - one makes us efficient, the other makes us dream bigger. It’s an episode filled with humility, humor, and yes.. human intelligence - proving that even in a world of algorithms, empathy still leads the way. Fun mentions as always: Chandana Fitzgerald Jeff Weness Milind Kamkolkar [00:00-02:00] Bloopers, sunshine, and background banter. [00:03-05:00] Alette’s third-culture upbringing — Japan, Hong Kong, Denmark. [00:05-07:00] Boarding school, biochemistry, and falling in love with proteins. [00:10-12:00] From academia to Pfizer — bringing science to life. [00:13-15:00] Leap to HealthXL — discovering digital health beyond the lab. [00:18-21:00] Entering Novartis — pre-ChatGPT AI strategy and innovation cycles. [00:22-25:00] Practical AI vs. game-changing AI — redefining productivity. [00:24-28:00] AI and drug discovery — startups, partnerships, and collaboration. [00:29-34:00] Lessons on open-minded leadership and partnering with purpose. [00:36-39:00] Jim’s classic closing story and Alette’s advice: Value your strengths, cherish your partners.

On episode #178 of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had a blast chatting with Jonathan Pearce, the thoughtful and forward-looking CEO of Masterlete - and previously the co-founder and CEO of Zipnosis, the company that pioneered asynchronous telemedicine long before it was mainstream. From balancing athlete-grade performance with mental resilience to building a company that refuses to compromise between data and empathy, Jon brings his trademark blend of humility and precision. He also opened up about his own mental health journey, reminding us that resilience isn’t just a leadership skill - it’s a human one. It’s an episode that reminds us - even in a world of algorithms and wearables, the human spirit still defines the win. 🔹 Top 5 Key Takeaways 💻 Lessons from Zipnosis: how DTC missteps became powerful playbooks 🤖 AI enables personalization - not replacement 🔥 Burnout prevention is the next performance edge 📊 From wearables to wisdom: data needs translation 🎯 Leadership = clarity, curiosity, and constant iteration Fun mentions as always: Pat Sukhum John Brownlee 00:00–02:30 — Welcome & banter: from sports metaphors to startup scars02:31–07:00 — Jon’s journey: building Masterlete and learning from athlete ecosystems07:01–12:30 — Data + empathy: the dual pillars of sustainable coaching12:31–16:00 — AI’s promise (and limits) in personal performance16:01–20:00 — Burnout and resilience: redefining “peak” for long-term success20:01–25:00 — The role of digital health platforms in preventive care25:01–30:00 — Leadership lessons: clarity, curiosity, and iteration in practice30:01–34:00 — Future of athlete engagement and real-time feedback34:01–38:00 — Building human connection in scalable tech models38:01–End — Lightning round + advice to Jon’s younger self

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had the pleasure of catching up with the one and only Mike McSherry, serial entrepreneur and CEO of Xealth, whose journey goes from quitting Microsoft in Australia to co-founding Boost Mobile, to building the infrastructure behind digital health prescriptions - and now joining forces with Samsung. We covered everything from startups, serendipity, and Surescripts, to what it means to be insanely curious (his words!) and to always find your foxhole friends. Oh, and there may have been a few humble-brags about being the guy who helped power billions of Android phones ad their keyboards. 🦾 🔹 Top 5 Key Takeaways 💡 Curiosity drives innovation - be “insanely curious” about everything. 📈 Luck favors persistence - serendipity comes from hard work. 🤝 Build with trust - surround yourself with “foxhole friends.” 🏥 Healthcare is hard - slow, bureaucratic, but worth transforming. 🌍 Samsung + Xealth - connecting home devices to health data. Fun mentions as always: HLTH USA Samsung Electronics UPMC Providence 📋 00:00 – 02:00 | Catching up with Jim & Eugene, Vegas talk, and welcoming Mike. 📋 02:00 – 06:00 | Mike’s journey from Microsoft to Australia’s biggest web dev company. 📋 06:00 – 09:00 | Lessons from being a “Navy brat” and world traveler. 📋 09:00 – 13:00 | Founding Boost Mobile and its wild telecom legacy. 📋 13:00 – 17:00 | From Nuance to Providence: the path into healthcare. 📋 17:00 – 22:00 | Building Xealth as the “Surescripts for digital health.” 📋 22:00 – 27:00 | Selling to providers and the hard reality of healthcare economics. 📋 27:00 – 33:00 | Integrating with Epic & Cerner: the friend-or-foe dance. 📋 33:00 – 41:00 | The Samsung acquisition story and its big vision for connected health. 📋 41:00 – 49:00 | The future of ambient healthcare and consent-driven data. 📋 49:00 – 52:00 | Mike’s advice: be curious, find your foxhole friends, stay humble.

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had the pleasure of hosting Jeff Weness, VP of Growth & Strategy at RefinedScience. From small-town Minnesota roots to global ventures in digital health and now tackling cancer with AI, Jeff’s journey is as unexpected as it is inspiring. We joked about handstands, Russian accents, and Netflix DVDs (yes, mailed in red envelopes!), but his career lessons are pure gold: listen deeply, solve real problems, and don’t be afraid to reinvent yourself. 🚀 🔑 Top 5 Key Takeaways 🎓 Career pivots can fuel long-term impact 🧑‍🤝‍🧑 Partnerships drive innovation in healthcare 🖥️ Geek Squad in hospitals = genius move 💊 Molecule + digital = future of pharma 🤖 AI is reshaping oncology discovery Fun mentions as always: Daniel Couchman Kendall Health Podcast Network John Brownlee Click Therapeutics, Inc. David Benshoof Klein Curio Digital Therapeutics Inc. HealthRHYTHMS Optum 📋 00:00–03:00 | Happy Wednesday banter & Jeff joins 📋 03:00–07:00 | Minnesota roots, 4-H, and Russia exchanges 📋 07:00–11:00 | Insurance career and pivot to MBA/venture 📋 11:00–14:00 | Best Buy innovation & Geek Squad in hospitals 📋 14:00–18:00 | Corporate partnerships at Children’s Minnesota 📋 18:00–23:00 | UnitedHealth & Optum Labs: data, R&D, and digital health 📋 23:00–28:00 | Otsuka: digital therapeutics, patience, and cultural insights 📋 28:00–33:00 | The molecule + digital debate in pharma 📋 33:00–38:00 | Refined Science: AI, oncology, and drug rescue 📋 38:00–46:00 | Cancer prevalence, longevity, and Jeff’s advice: listen deeply

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I welcomed Mark S. Gaunya, GBA, LIA - benefits innovator, wrestling fanatic, rugby convert, and author - who’s on a mission to transform healthcare from a cost center into an asset. From cutting weight in high school wrestling to cutting healthcare costs, Mark brings equal parts grit, vision, and humor to the conversation. Some highlights: 🤼 Wrestling built resilience, discipline, and vision. 📊 Finance background fuels entrepreneurial leadership. 🏥 Healthcare system works well but for the system itself.... 📖 Insurance captives and small businesses We also talked about his new book "Captivated Health: Take Control. Gain Transparency. Leverage Confidence " (pre-order on Amazon - https://www.amazon.com/Captivated-Health-Control-Transparency-Confidence-ebook/dp/B0FDLRTN3M/ref=sr_1_1?crid=2K4OHVOK90G8X&dib=eyJ2IjoiMSJ9.Tm_j3D1shFbNcCw4NyAf7g.KQWzsyxI7bcNVqKl8zp1DYjpRcHsutI26QEvGZx-fIw&dib_tag=se&keywords=Captivated+Health%3A+Take+Control.+Gain+Transparency.+Leverage+Confidence&qid=1758741583&sprefix=captivated+health+take+control.+gain+transparency.+leverage+confidence%2Caps%2C168&sr=8-1) Fun mentions as always: Megan Donnell, MBA, PHR, SHRM-CP, Amanda Goltz, Jennifer Borislow CLU [00:00–02:00] Welcome & pronunciation of “Gaunya” [02:00–06:00] Family roots in healthcare & entrepreneurship [06:00–10:00] Wrestling, resilience, and rugby adventures [10:00–15:00] Finance background → entrepreneurial foundation [15:00–20:00] Transition to insurers: Blue Cross, Cigna, Destiny [20:00–26:00] Leadership lessons, early management challenges [26:00–34:00] Captivated Health model & balance sheet strategy [34:00–39:00] Captives, PBMs, and real employer ROI stories [39:00–49:00] NABIP Consumer Bill of Rights & policy vision [49:00–55:00] Advice to younger self: “Pick wisely”

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I welcomed Jason Campana, the freshly minted CEO of LifeSpeak Inc. who once learned business the hard way - running a painting company without knowing how to paint. From questionable brush strokes to scaling global wellness platforms, Jason’s career is proof that grit beats polish. Fun mentions as always: John Brownlee Kyle Rolfing Jason Von Bank Michael Held All Roads Lead to Minneapolis – Serendipitous intro & John Brownlee connection (00:00–02:00) Jason’s Early Hustle – Bootleg CDs & paper routes (02:00–04:00) College Pro Days – Painting houses, cold sales, and leadership lessons (04:00–07:00) From Paint to Fitness – Joining Fitness on Request → Wellbeats (07:00–10:00) Scaling Corporate Wellness – Pivot to digital, COVID growth, LifeSpeak acquisition (10:00–13:00) Going Public (and Back Private) – IPO, acquisitions, lessons learned (13:00–19:00) Holistic Wellbeing at LifeSpeak – Fitness, mental health, caregiving, substance use (16:00–20:00) AI & Integration – Personalization, platform unification, future of prevention (20:00–24:00) M&A Lessons – Integration pains, cultural challenges, COO perspective (25:00–28:00) What’s Next – New go-to-market, partnerships, prevention at scale (40:00–45:00)

After a summer podcasting break, Jim Joyce and I are back and on this episode of #TheShot of #DigitalHealth Therapy, we finally cornered the legendary Erik de Heus, CEO of SkinVision (yes, only 173 episodes in… shame on us). From biking along Amsterdam canals to catching curveballs in Dutch baseball, to scaling energy startups and now leading SkinVision, Erik’s story is a mix of persistence, humility, and “just follow your dream” wisdom. If you’ve ever wondered how a kid bossing his friends on the playground ends up building digital health business that catch melanoma early and save lives at scale - this one’s for you. Fun mentions as always: Steve Seuntjens HLTH Inc. Martin Kelly ⧉ 00:00 – 02:00 | Opening banter – Jim & Eugene finally get Erik on the mic. ⧉ 02:00 – 06:00 | Early career & HP days – Amsterdam to California and back. ⧉ 06:00 – 09:00 | Childhood & sports – Football, baseball, and bossing friends. ⧉ 10:00 – 15:00 | Energy startup journey – From inception to €500M revenue. ⧉ 15:00 – 20:00 | Scaling challenges – Processes, people, and persistence. ⧉ 22:00 – 28:00 | Philips DirectLife – Competing with Fitbit + coaching layer. ⧉ 30:00 – 33:00 | Birth of PHS Capital – Early digital health investing. ⧉ 34:00 – 41:00 | SkinVision origins – Melanoma detection at scale. ⧉ 42:00 – 47:00 | Aligning incentives – Insurance, NHS, and consumer trust. ⧉ 47:00 – 54:00 | Erik’s advice & future vision – Follow your dream, validate the problem.

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I sit down with the Browns-abandoning, innovation-obsessed Peter Antall, MD. From dissecting cadavers to dissecting telehealth workflows, Peter shares his remarkable journey from pediatrician to healthtech pioneer - building national networks, taming 50 state regulations, and now, nudging GLP-1 users into long-term success. We also find out what gross anatomy has to do with true love. 💀❤️ Fun mentions as always: Olia Hibbard Naomi Allen Roy Schoenberg MD MPH Ido Schoenberg Ken Cahill Murray Brozinsky Julia Hu Neko Health 00:00 – Intro, garage jokes, and Peter’s warm welcome 02:30 – Growing up in Cleveland, med school romance 06:30 – Pediatrics, oncology dreams & the innovation gene 09:00 – Writing Pocket Pediatrician & symptom logic 11:00 – First telehealth forays: Specialists on Call 12:30 – Joining Amwell & the shift to consumer-grade video 18:00 – Why video > audio in clinical care 21:00 – Regulatory nightmare: 50 states, 7 were clear 23:30 – Never a malpractice case: 6M+ visits at Amwell 26:00 – AI note-taking & ambient documentation in care 30:00 – Going public with Amwell & moving on 31:30 – Brightline: Kids’ behavioral health & point solution woes 34:30 – Loneliness across all ages—tech as remedy or divider? 38:00 – Why Lark: scalable, daily AI + coach care 44:00 – GLP-1 support model: 80% persistence at 7 months 48:00 – Advice to young Peter: Think big, disrupt wisely

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I freeze time (and nearly our toes) with the extraordinary Dr Jack Kreindler -longevity doctor, tech founder, and Antarctic explorer. This is only our second-ever long-form episode, and we couldn't be more honored to have Jack join us for it. From designing UX with Douglas Adams to running diagnostics in sub-zero temperatures, Jack shares wisdom at the intersection of tech, healthspan, and philosophy. Yes, there's creatine. Yes, there's metaphysics. And yes, you’ll want to rethink your bedtime and your bucket list. It’s a ride through resilient humans, wild biohacks, and the hilarious humility of medicine in the age of AI. Dont miss this episode: Fun mentions as always: Daniel Kraft, MD Jordan Shlain, MD Peter H. Diamandis ☀️Maneesh Juneja Vishal Gulati 00:00:00 - Jack’s origin story: From tech to medicine 00:05:00 - UX with Douglas Adams & first tech ventures 00:12:00 - Founding CHHP & insights into performance science 00:21:00 - Commitment, coaching, and who makes it through 00:30:00 - The biohacking movement: Hope, hype, and hazards 00:41:00 - The pursuit of longevity vs acceptance of death 00:49:00 - Preventive diagnostics & experience design (Neko, Echo) 00:58:00 - AI in medicine: Augmenting empathy & reducing burnout 01:06:00 - WellFounded & experiential medicine adventures 01:18:00 - South Pole expedition & commencement reflections

On this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I went from cowbells to code to campaign trails with the one and only Owen McCarthy. We covered a LOT: ✅ Bootstrapping MedRhythms from a napkin sketch to FDA approval ✅ Licensing Stevie Wonder’s music to help stroke patients walk again ✅ Why Maine needs robotic homes (and maybe fewer regulations) ✅ How it feels to run for Governor with a quick thought on the Big Beautiful Bill ✅ oh... and even spoke about the very real Uncle Thump (not Trump) Owen’s journey from logging trucks to legislative vision is the very definition of full circle. And spoiler: you don’t want to miss his advice to future founders 👇 Fun Mentions as always: Steve Seuntjens Marco Mohwinckel Roberto Ascione William Stevens Tech Tour Brian Harris Ann Mond Johnson Megan Coder 00:00–02:00 — Opening from Switzerland: Cowbells, Confessions & TechTour Hosts kick off with scenic vibes and introduce Owen from a mountaintop moment. 02:00–04:30 — Roots in Rural Maine: Logging, Cows & College Dreams Owen shares his upbringing in Patten, Maine, with stories of family, hard work, and dad’s unforgettable advice. 04:30–08:30 — From Engineering to Entrepreneurship: How MedRhythms Started From water treatment sales to Harvard to building a healthtech company with heart (and rhythm). 08:30–14:00 — Bootstrapping to Breakthrough: MedRhythms, Brian Harris & Real Outcomes The early days of therapy, scaling manually, and why universal music licensing took 18 months. 14:00–16:30 — Working with Stevie Wonder: Music, IP, and Big Biz Buy-In The surprising (and charming) tale of pitching Universal and name-dropping Stevie mid-deal. 16:30–21:00 — Defining DTx: Alliance Building, Policy Work, and Lessons Learned What it takes to create an industry from scratch, and why “starting with reimbursement” matters. 21:00–24:00 — The Case for Rural Tech: Healthcare Access in Remote Maine Why digital care and EMS are urgent lifelines in the U.S.’s oldest and second-most rural state. 24:00–27:30 — Jumping into Politics: What Drove Owen to Run for Governor Owen reflects on his decision to run, family conversations, and chasing calm in the hurricane. 27:30–37:30 — Platform Breakdown: Housing, Energy, Healthcare & Modular Dreams A detailed look at his policies: robotic homes, energy equity, and cancer care via telehealth. 37:30–43:00 — Legacy, Leadership & Advice to Future Founders From Uncle Thump to reimbursement-first strategy, Owen gets real about impact and longevity.

Who knew that picking up that Yellow pages at age 24 would lead to Big Brothers Big Sisters Twin Cities ? In this episode #169 of #TheShot of #DigitalHealth Therapy, Jim Joyce & I spoke to Pat Sukhum who took us from attic-living startup grit to changing lives at scale - 2200 youths and counting. We talked Definity Health (sold to United), RedBrick Health (sold to Virgin), Thai food, and why the humble leader is the fiercest force for good. There’s wisdom, there’s vulnerability, there’s even an IRS - Harvard study drop. Pat proves you can be both a CEO and a sidekick, and still lead with heart. Just a few highlights: 🧒 Mentorship isn’t charity, it’s shared transformation. 🤝 Relationships power nonprofit scale and social change. 🧭 Belief plus humility = true leadership growth. 💙 Oh - and don’t forget to say hi to your inner shy kid. Fun mentions as always: John Brownlee Kyle Rolfing Dave Dickey Anthony Miller Daniel Couchman Kendall TimestampTopic Summary[00:00:00]–[00:02:00]Show intro and Pat joins the session[00:02:00]–[00:04:00]Pat’s Minnesota roots and Thai-American identity[00:04:00]–[00:07:00]Early assimilation and family background[00:07:00]–[00:10:00]High school, identity crisis, and Carleton College[00:10:00]–[00:13:00]Deloitte days and founding Definity Health[00:13:00]–[00:17:00]The Big Brothers Big Sisters call and early match[00:17:00]–[00:22:00]Consumer-driven care and Definity’s acquisition[00:22:00]–[00:26:00]RedBrick Health and behavior change lessons[00:26:00]–[00:30:00]Consulting, Bind, and learning to sell[00:30:00]–[00:45:00]CEO transition, mission-driven work, and future vision

⚠️ Warning: Listening to this episode may cause spontaneous inspiration, side effects include rethinking innovation, falling in love with Denmark, and Googling “intelligent bricks.” Meet Anne C. Fleischer — engineer, innovator, former LEO Pharma exec, and now leading Consumer Engagement & New Business Models for Obesity at Novo Nordisk. She grew up in a village so small that your soccer team was whoever showed up to class that day. She wanted to be a helicopter pilot or a doctor, but got motion sickness and couldn’t get into med school...... So she built a new path- literally - constructing heart pump mannequins, NFC-enabled pavement tiles, and eventually digital health products that helped millions. 💥 This episode is a masterclass in doing things differently—with a sense of humor, a killer vision, and a very Danish ability to keep it real. PS. See the link below in comments for a new partnerships portal that the team at Novo announced today at HLTH Europe Fun mentions as always: Malin Johansson Anish Shindore Steve Seuntjens Erik de Heus SkinVision Chandana Fitzgerald Jonathan Weiner Rich Scarfo HLTH Inc. Michael Pace Marina Borukhovich Ali Hashemi Tom Hale 00:00 From Danish Countryside to Dreams of Medicine 07:00 Engineering Meets Creativity 11:00 Building Intelligent Bricks & Early Innovations 13:00 From Fuel Cells to Pharma Strategy 15:00 Founding Leo Innovation Lab 19:00 Build vs. Buy: Pharma’s Digital Dilemma 22:00 Creating Leo Ventures 24:00 Novo Nordisk: Tackling Obesity with Empathy 29:00 Feelings That Shape Health Outcomes 44:00 Anne’s Advice: Speak Boldly, Share Your Purpose

Picture this: you’re 7 years old, just got rejected from every game on the block, so you cannonball into the YMCA pool… 15 years later, you’re one of the top U.S. swimmers. Fast forward another few decades, you’re sitting at a desk once occupied by Andy Molnar at Pear, building the digital health reimbursement movement one payer at a time. 🧠💥 This week on #TheShot of #DigitalHealth Therapy Jim Joyce and I dive into OG territory with Michael Pace, the swimming, startup-slaying, palm-loving advisor. 🔍 MAHA Movement 🖥️ Digital Health’s Role in New Administration Policies 💊 DTx and the Reimbursement Policy 🧠 PDURS Software Guidelines: Pharma Meets Digital 🧩 Trump's executive order on pharma pricing... 👇 Hit play.

Ever wonder what happens when a German economics grad skips the surf lessons in Sydney and builds one of Australia’s fastest-scaling startups? Farina Schurzfeld did exactly that — and then turned the same operational firepower toward mental health. In this episode of #TheShot of #DigitalHealth Therapy, Jim Joyce and I speak with Farina who shares her journey from launching Groupon in Australia to co-founding Selfapy (Germany’s leading digital mental health platform) and taking it through the bureaucratic gauntlet of DiGA approval - before stepping back to build AndRobin, a sidekick-for-hire growth and ops squad. 💻 Fast growth isn't sustainable without long-term thinking and ethical grounding. 🛒 What scales in e-commerce doesn’t always translate to regulated, B2B-driven systems. 🏥 Selfapy didn’t start with DiGA—but became a pioneer anyway. They built for users, then adapted as policy opened the reimbursement door. 🛠️ Startups need senior operators, not just advisors or consultants AndRobin fills the Series A void with hands-on executional leadership. 🚪 Step out when your superpower isn’t needed anymore 👇If you're in digital health, health tech, or just building something that matters - this one’s for you Fun mentions as always: Roberto Ascione Frontiers Health Andrew Mason Bundesinstitut für Arzneimittel und Medizinprodukte hims & hers

What do William Wallace, smart pill bottles, and pharma sales have in common?They all showed up in this week's #TheShot of #DigitalHealth Therapy. Jim Joyce and I had a chat with Innes Meldrum - Scottish-born, New Jersey-rooted CEO of AdhereTech. Innes unpacks his journey from flunking high school to running $Big brands and now cracking one of healthcare’s stickiest problems: medication adherence. We covered: 🤖 Tech vs. human behavior in adherence 🧩 Pharma’s paradox (have to watch to get more) 🧠 Leadership = authenticity + heart 🫥 Tech must be invisible for patients 📈 Adherence is greater than acquisition in long run Big lessons. Big heart. Big impact. 🎧 Listen now and learn why belief might just be your biggest asset. Fun mentions as always: Josh Stein Dave Griffiths 🇮🇪 Kaiser Permanente YourCoach.Health 00:00 – 03:00 — Opening Banter & Setup Eugene, Jim & Innes kick things off across time zones with laughs and backstory. 03:00 – 08:00 — From Scotland to Kentucky Innes shares his multicultural roots, flunking high school, and a summer teaching soccer in the US. 08:00 – 14:00 — Career Leap: Tech to Pharma The unexpected journey from engineering at Nortel to global marketing at Novartis. 14:00 – 18:00 — Mental Health & Authentic Leadership How neuroscience drew Innes in—and why emotional connection is key to commercial success. 18:00 – 22:00 — Joining AdhereTech Why Innes took the CEO seat and what surprised him when he arrived. 22:00 – 27:00 — Solving the Adherence Problem A dive into AdhereTech’s smart pill bottle and how it’s changing patient behavior. 27:00 – 32:00 — Pharma Economics & Ownership Gaps The financial burden of non-adherence—and who really owns the problem in healthcare. 32:00 – 36:00 — Stress, Behavior, and Health Coaching Exploring the real reasons patients don’t take meds—and how health coaching can help. 36:00 – 41:00 — Resilience & System Innovation Innes reflects on leadership growth, system constraints, and building a startup culture. 41:00 – 45:00 — Future Vision & Final Advice A keynote moment: belief, purpose, and what Innes would tell his younger self.