The Incubator's Journal Club

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The Incubator's Journal Club

Ben Courchia MD & Daphna Yasova Barbeau MD

124 episodes

6 hours ago

In this Journal Club episode of the Incubator Podcast, Ben Courchia and Daphna Yasova-Barbeau review a study from the Journal of Perinatology evaluating NT-proBNP as a diagnostic tool for chronic pulmonary hypertension in extremely preterm infants. The discussion walks through the clinical burden of pulmonary hypertension in babies with bronchopulmonary dysplasia, the limitations of echocardiography, and the appeal of accessible biomarkers. Using data from a SickKids Toronto cohort, the hosts...

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Health & Fitness

All content for The Incubator's Journal Club is the property of Ben Courchia MD & Daphna Yasova Barbeau MD and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.

In this Journal Club episode of the Incubator Podcast, Ben Courchia and Daphna Yasova-Barbeau review a study from the Journal of Perinatology evaluating NT-proBNP as a diagnostic tool for chronic pulmonary hypertension in extremely preterm infants. The discussion walks through the clinical burden of pulmonary hypertension in babies with bronchopulmonary dysplasia, the limitations of echocardiography, and the appeal of accessible biomarkers. Using data from a SickKids Toronto cohort, the hosts...

Show more...

Health & Fitness

Episodes (20/124)

The Incubator's Journal Club

#393 - [Journal Club] - 📌 Can NT-proBNP Guide Clinical Suspicion of Chronic Pulmonary Hypertension?

In this Journal Club episode of the Incubator Podcast, Ben Courchia and Daphna Yasova-Barbeau review a study from the Journal of Perinatology evaluating NT-proBNP as a diagnostic tool for chronic pulmonary hypertension in extremely preterm infants. The discussion walks through the clinical burden of pulmonary hypertension in babies with bronchopulmonary dysplasia, the limitations of echocardiography, and the appeal of accessible biomarkers. Using data from a SickKids Toronto cohort, the hosts...

23 hours ago

20 minutes

The Incubator's Journal Club

#392 - [Journal Club] - 📌 Do Antenatal Corticosteroids Improve Survival for Babies Born at 21–24 Weeks?

In this Journal Club episode, Ben and Daphna review a large national cohort study examining the association between antenatal corticosteroid exposure and survival in extremely preterm infants born between 21 and 24 weeks’ gestation. They discuss biologic plausibility, practice variation, and the challenges of interpreting retrospective data, while focusing on how these findings may inform counseling and shared decision-making at the margins of viability. ---- The Effects of Antenatal Corticos...

4 days ago

15 minutes

The Incubator's Journal Club

#392 - [Journal Club] - 📌 Could Longer Caffeine Treatment Reduce Hypoxia and Speed Discharge?

Ben and Daphna review the ICAF randomized clinical trial evaluating extended caffeine therapy in preterm infants and its impact on intermittent hypoxia through 41 weeks postmenstrual age. They discuss the study design, oximetry outcomes across multiple saturation thresholds, inflammatory biomarkers including TNF-α, and clinically relevant safety signals such as oxygen restart rates, length of stay, and weight gain. The conversation focuses on what intermittent hypoxia may mean for ongoing ris...

5 days ago

13 minutes

The Incubator's Journal Club

#392 - [Journal Club] - 📌 Early Outcome Data After Resuscitation at 21 Weeks’ Gestation

In this Journal Club episode, Ben and Daphna review a salient study from JAMA Network Open examining outcomes of infants born at 21 weeks’ gestation at the University of Iowa. They walk through resuscitation practices, early physiologic challenges, survival trends, and short-term developmental outcomes, while placing the data in the broader context of shifting limits of viability. The discussion highlights both cautious optimism and the many unanswered questions that remain as neonatology con...

6 days ago

26 minutes

The Incubator's Journal Club

#392 - [Journal Club] - 📌 Is PDA Treatment Doing More Harm Than Good in Preterm Infants?

In this Journal Club episode, Ben and Daphna review a major randomized clinical trial published in JAMA comparing expectant management with active pharmacologic treatment of patent ductus arteriosus in preterm infants. They walk through the trial design, inclusion criteria, and outcomes, highlighting the unexpected survival difference favoring expectant management despite similar rates of bronchopulmonary dysplasia. The discussion explores the implications for bedside decision-making, the lim...

1 week ago

20 minutes

The Incubator's Journal Club

#388 - [Journal Club Shorts] - 📌 Can Maternal Mental Health Predict Neurodevelopmental Delays in Toddlers?

Maternal Psychological Distress Before and After Childbirth and Neurodevelopmental Delay in Toddlers. Matsumura K, Tanaka T, Kuroda M, Tsuchida A, Hatakeyama T, Kasamatsu H, Inadera H; Japan Environment and Children’s Study Group.JAMA Netw Open. 2025 Oct 1;8(10):e2540907. doi: 10.1001/jamanetworkopen.2025.40907.PMID: 41171271 Free PMC article. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the sh...

1 week ago

13 minutes

The Incubator's Journal Club

#388 - [Journal Club Shorts] - 📌 EBNEO Commentary - Treatment of Hypotension of Prematurity: a randomised trial.

Treatment of Hypotension of Prematurity: a randomised trial. Alderliesten T, Arasteh E, van Alphen A, Groenendaal F, Dudink J, Benders MJ, van Bel F, Lemmers P. Arch Dis Child Fetal Neonatal Ed. 2025 Dec 15;111(1):F60-F66. doi: 10.1136/archdischild-2024-328253.PMID: 40413017 Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or cont...

1 week ago

22 minutes

The Incubator's Journal Club

#371 - [Journal Club Shorts] - 📌 Risk Factors for NEC in Preterm Infants on an Exclusive Human Milk Diet

Risk factors associated with the development of necrotizing enterocolitis in preterm infants on an exclusive human milk diet: a single-center case-control study. Ailumerab H, Miller JL, DeShea L, Beasley WH, Chaaban H, Bergner EM.J Perinatol. 2025 Aug 30. doi: 10.1038/s41372-025-02401-2. Online ahead of print.PMID: 40885806 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram...

1 week ago

16 minutes

The Incubator's Journal Club

#388 - [Journal Club Shorts] - 📌 Does Early High-Volume Feeding Improve Body Composition in Preterm Infants?

Early body composition outcomes of infants born very preterm and receiving high volume, human milk feedings (≥170 ml/kg/day) before postnatal day 14. Gunawan E, Molleti M, Salas AA.J Perinatol. 2025 Oct 31. doi: 10.1038/s41372-025-02469-w. Online ahead of print.PMID: 41174086 No abstract available. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast....

1 week ago

8 minutes

The Incubator's Journal Club

#388 - 📑 Journal Club - The Complete Episode from December 21st 2025

In this Journal Club episode, Ben and Daphna review five recent studies with practical implications for neonatal care. The FEED1 trial examines whether starting full milk feeds from day one is safe in 30-32 week preterm infants, finding no difference in length of stay compared to gradual feeding but fewer central line days. A brief communication from UAB explores high-volume feeding strategies (≥170 ml/kg/day) and their impact on body composition in very preterm infants. The hosts discuss a ...

1 week ago

1 hour 25 minutes

The Incubator's Journal Club

#371 - 📑 Journal Club - The Complete Episode from October 26th 2025

What’s new in neonatal innovation and research this week? Join Ben and Daphna for a lively Journal Club episode of The Incubator Podcast, recorded after a long NICU day but packed with energy and insight. They begin with an update on the newly released NRP 9th Edition, preview their excitement for the upcoming Delphi Neonatal Innovation Conference, and then dive into five remarkable studies shaping neonatal care. From the use of CARPEDIEM for renal replacement therapy in the tiniest infants...

1 week ago

1 hour 11 minutes

The Incubator's Journal Club

#371 - [Journal Club Shorts] - 📌 EIT-Guided PEEP Optimization in Severe Bronchopulmonary Dysplasia

Identifying optimal positive end-expiratory pressure with electrical impedance tomography guidance in severe bronchopulmonary dysplasia. Shui JE, LaVita CJ, Alcala GC, Nichols JH, Jassar RK, Turcu RM, Lerou PH, Cereda MF, Carroll RW, Ribeiro De Santis Santiago R, Berra L.J Perinatol. 2025 Sep 30. doi: 10.1038/s41372-025-02433-8. Online ahead of print.PMID: 41028823 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You c...

1 week ago

12 minutes

The Incubator's Journal Club

#388 - [Journal Club Shorts] - 📌 Are forces applied to a baby's airway lower with video laryngoscopy?

Applied forces during neonatal intubation with direct and video laryngoscopy at different bed elevations: a randomized crossover manikin study. Cavallin F, Pasquali G, Maglio S, Villani PE, Menciassi A, Tognarelli S, Trevisanuto D.Eur J Pediatr. 2025 Nov 5;184(12):732. doi: 10.1007/s00431-025-06524-8.PMID: 41191125 Free PMC article. Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact t...

1 week ago

14 minutes

The Incubator's Journal Club

#388 - [Journal Club Shorts] - 📌 Should Preterm Infants Receive Full Feeds from Day One?

Full exclusively enteral fluids from day 1 versus gradual feeding in preterm infants (FEED1): a open-label, parallel-group, multicentre, randomised, superiority trial. Ojha S, Mitchell EJ, Johnson MJ, Gale C, McGuire W, Oddie S, Hall SS, Meakin G, Anderson J, Partlet C, Su Y, Johnson S, Walker KF, Ogollah R, Mistry H, Naghdi S, Montgomery A, Dorling J; FEED1 collaborative.Lancet Child Adolesc Health. 2025 Dec;9(12):827-836. doi: 10.1016/S2352-4642(25)00271-8. Epub 2025 Oct 17.PMID: 41115446 F...

1 week ago

15 minutes

The Incubator's Journal Club

#388 - [Journal Club Shorts] - 📌 Can We Predict Which Extremely Preterm Infants Need Early Cord Clamping?

Antenatal Prediction of Early Cord Clamping among Infants Born Extremely Preterm. Katheria A, Dorner RA, Grobman W, Rysavy MA, Koo J, Wyckoff MH, Sandoval G, DeMauro SB, Das A, Lee HC, Cotten M, Calvo L, Saha S; Eunice Kennedy Schriver National Institute of Child Health and Human Development Neonatal Research Network.J Pediatr. 2025 Oct 31:114878. doi: 10.1016/j.jpeds.2025.114878. Online ahead of print.PMID: 41177398 Support the show As always, feel free to send us questions, comments, or s...

1 week ago

14 minutes

The Incubator's Journal Club

#364 - [Journal Club Shorts] - 📌 Improving Neonatology Staffing With the INS Toolkit

Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

1 week ago

16 minutes

The Incubator's Journal Club

#364 - [Journal Club Shorts] - 📌 How Do Neurodevelopmental Outcomes Compare After Transcatheter PDA Closure Versus Surgical Ligation in Extremely Preterm Infants?

Comparison of neurodevelopmental outcomes of extremely preterm infants undergoing trans-catheter closure of the patent ductus arteriosus compared to surgical ligation. Kaluarachchi DC, Chock VY, Do BT, Rysavy MA, Sankar MN, Laughon MM, Backes CH, Colaizy TT, Bell EF, McNamara PJ, Hintz SR, Natarajan G.J Perinatol. 2025 Sep 23. doi: 10.1038/s41372-025-02417-8. Online ahead of print.PMID: 40987835 Support the show As always, feel free to send us questions, comments, or suggestions to our emai...

1 week ago

10 minutes

The Incubator's Journal Club

#371 - [Journal Club Shorts] - 📌 Nebulized Nitroglycerin for Persistent Pulmonary Hypertension of the Newborn

Nebulized nitroglycerin as an adjuvant drug in management of persistent pulmonary hypertension of newborns: a randomized controlled trial. Farag MM, Ghazal HAE, Abdel-Mohsen AM, Rezk MA.Eur J Pediatr. 2025 Sep 1;184(9):586. doi: 10.1007/s00431-025-06381-5.PMID: 40888971 Free PMC article. Clinical Trial. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupod...

1 week ago

11 minutes

The Incubator's Journal Club

#364 - [Journal Club Shorts] - 📌 Does DHA With or Without ARA Supplementation Improve Outcomes in Preterm Infants? A Meta-Analysis

Effect of enteral supplementation of DHA with or without ARA in preterm infants: a meta-analysis. Dang D, Gao Z, Zhang C, Mu X, Lv X, Wu H.Arch Dis Child Fetal Neonatal Ed. 2025 Apr 15:fetalneonatal-2024-327606. doi: 10.1136/archdischild-2024-327606. Online ahead of print.PMID: 40233974 Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact ...

1 week ago

12 minutes

The Incubator's Journal Club

#364 - [Journal Club Shorts] - 📌 Are Infants With Critical Congenital Heart Disease at Higher Risk for Cancer in the First Year of Life?

Critical Congenital Heart Disease and Infant Cancer. Chin S, Lupo PJ, Baer R, Hobbs CA, Chambers CD, Bandoli G.Pediatrics. 2025 Sep 25:e2025072934. doi: 10.1542/peds.2025-072934. Online ahead of print.PMID: 40992753 No abstract available. Support the show As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profile...

1 week ago

7 minutes