Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:

• The risk of postoperative endophthalmitis after cataract surgery is significantly greater in eyes with uveitis, corticosteroid use, and immunosuppressant use.

• Pediatric patients who undergo lensectomy for traumatic cataracts have low likelihood of achieving age-normal visual acuity, with nearly 50% requiring a secondary surgery for visual axis opacification. 

• Fishing-related ocular injuries are on the decline, however they continue to be a large cause of corneal abrasions, contusions, and intraocular foreign bodies. Fishhooks and lures are the most common culprits.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:

• The incidence of sports-related orbital fractures in the U.S. has remained stable over the past decade, with baseball, cycling, and softball as leading causes.

• GLP-1 receptor agonist use in non-diabetic patients who are overweight or obese reduces risk of developing dry AMD.

• Changes in cup-to-disc ratio alone are unreliable for predicting glaucoma progression.

• Metformin protects against developing primary open-angle glaucoma in adults aged 40 years and older with diabetes.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:

• Pre-exposure prophylaxis nucleoside and nucleotide reverse transcriptase inhibitors found to be associated with an increased risk of primary open angle glaucoma.

• New study finds additional systemic drugs that could increase patient risk of macular toxicity.

• Retinopathy of prematurity is found to have a place-based association with a child’s neighborhood as measured by the childhood opportunity index.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss…

• Corticosteroids and DMARDs together were found to be superior to corticosteroids alone in treating non-anterior sarcoid uveitis. 

• Thousands of Americans have come to the ED over the past few years for pickleball-related ocular traumas, suggesting eye protection could be beneficial in this sport. 

• Glaucoma is associated with sleep-wake and Circadian rhythm disorders, likely secondary to damage to the RGCs and optic nerve causing irregular regulation of sleep-wake physiology.

• Novel statin nanoparticles injected intravenously can preserve and even double cone photoreceptors in retinitis pigmentosa mouse models by reducing inflammation.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss…

• A cohort study of NASA astronauts found that those who developed spaceflight-associated neuro-ocular syndrome during one long-duration mission were highly likely to develop it again on subsequent missions.

• Strabismus surgery is undervalued by Medicare, as evidenced by a surgical cost analysis underscoring the need for fair compensation to address the growing shortage of strabismus surgeons and ensure patient access to care.

• For acute acquired comitant esotropia, augmented medial rectus recession surgery achieved significantly better long-term eye alignment, fusion, and quality-of-life outcomes than botulinum toxin A injection.

In this episode, Dr. Sandra Lora Cremers joins us to explore the rising prevalence of dry eye disease and its impact on patients. We discuss how modern lifestyles and screen use are changing ocular surface health, the early warning signs not to overlook, simple and effective prevention strategies, and the innovative treatments shaping the future of dry eye care.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:

• Cultured corneal endothelial cell transplants maintained clear corneas and vision for up to 10 years, offering a scalable alternative to donor tissue.
• Long-term atropine use for myopia control showed no increased risk of cataract, glaucoma, or maculopathy in a nationwide cohort.
• Patients with giant cell arteritis had higher 5-year risks of aortic aneurysm and carotid stenosis, especially those with visual symptoms.
• Higher omega-3 fatty acid levels were linked to a significantly lower risk of developing primary open-angle glaucoma.

In this episode, Dr. David J Palmer, MD joins us as we dive into the topic of sustainability in ophthalmology. We explore three of the most environmentally pressing issues in ophthalmology today and hear about various studies, organizations, and resources that support efforts to make ophthalmology greener. 

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:

• The incidence of ocular surface squamous neoplasia in the US nearly tripled from 2014 to 2021.
• Trabeculectomy with mitomycin C fails more often in Hispanic patients.
• Ocular and orbital trauma in intimate partner violence identifies high-risk patients with elevated mortality, underscoring the need for early protective intervention.
• Swept-source AS-OCTA detects corneal vasoconstriction, showing reduced flow area and potential for monitoring neovascularization.
• Early-onset inherited retinal diseases show distinct refractive error shifts, highlighting the need for early screening and intervention.

In this episode, Dr. Puente joins us for a conversation about disability in ophthalmology from a clinical perspective - exploring successes, identifying gaps, and sharing lessons that can help shape more accessible eye care for the future.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode, we discuss:

• Asymmetric Multi-point Defocus Technique (AMDT) lenses reduced myopia progression in children compared with single-vision lenses

• There was no improvement in vision with the addition of corticosteroids or corneal cross-linking in the treatment of bacterial keratitis

• Tear cell-based assays had a greater sensitivity than serum in detecting ocular myasthenia gravis

• Antioxidant protein DJ-1 may be protective against the mechanisms behind diabetic keratopathy

Too busy to read The Lens? Listen to our weekly summary here! In this week’s episode we discuss:

• Genetic predisposition determined by polygenic risk score can predict glaucoma risk and visual field loss pattern.

• Patients receiving GLP-1 Receptor Agonists had a lower risk of developing uveitis.

• One-third of corneal perforations still required penetrating keratoplasty after glue treatment.

In This Week's Issue:

• A cross-sectional study looking at patients after globe removal from US service members showed higher rates of suicidal ideation, alcohol use disorder, anxiety/depression, among other behavioral health diagnoses.
• As compared to European populations, Hispanic populations had lower success rates and higher bleb leaks with trabeculectomy.
• A post hoc analysis found that younger adjusted age at congenital cataract surgery was associated with higher glaucoma risk but better long-term visual acuity, whilegestational age alone was not associated with outcomes.
• H. pylori-positive patients developed temporal retinal nerve fiber layer thinning at slightly higher rates and also developed signs of macular degeneration at a significantly younger age than H. pylori-negative patients

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss…

• Ocular vascular occlusion is a rare complication of soft tissue filler injections that can cause vision loss
• Semaglutide may be associated with various ocular adverse effects, most notably increased risk of developing non-arteritic anterior ischemic optic neuropathy
• Glaucoma development is linked to poor sleep habits, insomnia, and sleep apnea
  

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss…

• In patients undergoing retinal detachment repair, patients with cannabis use had significantly less proliferative vitreoretinopathy compared to patients without. 

• Chronic oral nitrate use may be protective against open angle glaucoma through vascular and neuroprotective mechanisms.

• Intravitreal injection for retinopathy of prematurity results in enlargement of the cup-to-disc ratio.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:

• CorNeat EverPatch shows high exposure and revision rates compared to human donor cornea grafts.

• Diversified segmental defocus optimization lenses show promise in preventing development of myopia in children.

• Screening and stroke workups in the ED for patients with central retinal artery occlusion have increased in the USA.

• IL-7 blockade outperforms IL-15 in treating chronic autoimmune uveitis.

• Modest IOP elevations in myopic normal tension glaucoma eyes may lead to progressive retinal nerve fiber layer thinning.

Too busy to read The Lens? Listen to our weekly summary here! In this week’s episode we discuss:

• Implantable devices such as EYEMATE-SC show promise in safely and accurately measuring intraocular pressure without the assistance of a clinician. 

• There is promise in using machine learning algorithms in glaucoma risk assessment as an objective tool for measuring retinal nerve fiber layer thickness from optic disc images.

• Hormonal contraceptive use confers a higher relative risk of retinal vein occlusion, though the relative risk of retinal vein occlusions is low.

Too busy to read the Lens? Listen to our weekly summary here! In this week's episode we discuss...

• Certain systemic medications for T2DM may increase DME risk, while others are protective, suggesting medication choice impacts retinal health.

• Daily low-dose valacyclovir reduces herpes zoster ophthalmicus-related recurrence at 18 months, supporting utility in long-term suppression.

• RVO incidence rose during the COVID-19 pandemic in South Korea among middle-aged adults, while RAO rates remained stable. 

• Nanopore sequencing shows promise for uveitis diagnosis, detecting herpes viruses with up to 75% sensitivity and 100% specificity.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss…

• Glaucoma is linked with circadian rhythm sleep disorders and other sleep-wake disturbances.

• Physical activity acutely increases IOP in glaucoma patients, returning near baseline during recovery, with IOP closely tracking blood pressure and heart rate changes.

Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss:

• Thickening of the retinal pigment epithelium-Bruch (brook) membrane is associated with both age-related macular degeneration progression and higher genetic risk scores. 

• Early glaucoma diagnosis may increase emotional distress in patients, even without noticeable vision loss.

• Patients with diabetes may not be at increased risk of postoperative endophthalmitis after cataract surgery, regardless of A1C levels.

• High cholesterol in the aging lens may help protect against cataract formation by preventing protein-membrane interactions.

• A multi-task artificial intelligence platform used ultra-wide-field fundus images to accurately detect and triage multiple retinal diseases—including diabetic retinopathy, glaucoma suspect, and age-related macular degeneration—with high area under curves and interpretability features, offering a scalable solution for real-world screening.