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In this episode Dr's J and Santhosh explore the medicine behind the music of some well known and lesser known songs. Along the way they cover the rolling stones, mother's little helper Miltown, the first psychiatric drug, the trouble trying to treat the heartbreak of Huey Lewis, the secret history of a spoonful of sugar and sabin sundays, imagine dragons chronic illness song, and a 1930s broadway song about an enthusiastic physician. So sit back and relax as we put a song in your heart of medical knowledge!
Further Reading
https://www.ncbi.nlm.nih.gov/books/NBK548721/
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IN this episode, Dr's J and Santhosh cover stories, studies, and general knowledge in their annual influenza special. Along the way they cover the poor decision making of the secretary for health and human services, the confluence of influenza and journal clubs, the original identification and discovery of the flu virus, a sneezy ferret, optimistic media, military vaccine testing, the discovery of seasonal flu changes, the art of flu surveillance, the damage done to surveillance by this administration, alternative vaccine production methods, dosing change recommendations and more! so sit back and catch some knowledge about whats coming to town!
Further Reading
https://utppublishing.com/doi/10.3138/jammi-2025-0025
https://www.cdc.gov/fluview/surveillance/2025-week-45.html
https://www.nejm.org/doi/full/10.1056/NEJMoa2416779?query=featured_home
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01742-8/abstract
https://www.ijidonline.com/article/S1201-9712(25)00322-4/fulltext
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In this episode Dr's J and Santhosh explore the history of off label prescribing of medications. Along the way they cover literature and the rise of food safety, the importance of legal phrasing, false statements versus false advertising, sulfanilamide tragedy of 1937, the creation of prescription and over the counter medications, the thalidomide scandal and the us physician who mostly prevented it, drug repurposing and some famous examples of off label uses for medication. So sit back and relax as we read the fine print on off label medications!
Further Reading
chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.fda.gov/files/about%20fda/published/The-Sulfanilamide-Disaster.pdf
https://www.pharmacytimes.com/view/pharmacys-past-the-soothing-syrup-known-for-causing-death-in-thousands-of-babies-#:~:text=Mrs.,to%20kill%20the%20average%20child.
https://www.medrxiv.org/content/10.1101/2022.09.08.22279709v1.full
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In this episode, Dr's J and Santhosh explore some of the creative ways medical issues have been addressed throughout the years. Along the way they cover surprising uses for nun urine, a heart stopping utilization of saran wrap, the rebellious lumberjack who changed cardiology forever and a reason to flood one's anus with hydrogen. SO sit back and relax as we cover some unusal solutions to modern problems!
Further Reading
https://pmc.ncbi.nlm.nih.gov/articles/PMC1430651/
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In this episode, Dr Santhosh takes the lead and educates Dr J on some great moments in public health. Along the way they cover medical tongue twisters, staphylococcus, toxic shock syndrome, menstruation, superantigens, deadly tampons, disease surveillance, product testing group b strep and more! So sit back and relax as Dr Santhosh takes us on a journey of public health!
Further Reading
https://www.sciencedirect.com/science/article/pii/S0140673678922742
https://academic.oup.com/jid/article/145/4/458/862059
https://www.nejm.org/doi/10.1056/NEJM198012183032501
https://www.fda.gov/consumers/consumer-updates/facts-tampons-and-how-use-them-safely
https://pmc.ncbi.nlm.nih.gov/articles/PMC8540901/
https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5910a1.htm
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In this episode, Dr's J and Santhosh dive into some studies and history of bodily fluids! Along the way they cover the crying classifications, tears on demand, the zone of inhibition, emotional leakage, limericks, the many suspected uses of saliva, recrements and excrements, congressional spittoons, fish sperm for wound healing, the science of sharts, harold and kumar go to whitecastle, and of course, the poop microbiome. So sit back and relax as we go all in on the things that come out of you!
Further Reading
https://www.inverse.com/innovation/fart-monitoring-ai
https://pmc.ncbi.nlm.nih.gov/articles/PMC7986284/
https://pmc.ncbi.nlm.nih.gov/articles/PMC6201288/
https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00360-4
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In this episode Dr's J and Santhosh peer deep into the windows of the soul to talk about ophthalmology. Along the way they cover the bangles and forced parodies, the oldest ophthalmology doctor and monument, eye anatomy in the time of ancient Greece, cataract couching in ancient India, the invention of eyeglasses and their european influence, fathering a scientific field, oculists and secret societies in Germany, early textbooks, the history of prosthetic eyes, the creation of an entire new field of surgery and the surprising medical studies behind sunglasses. SO sit back and relax as we attempt not to blind you with science of eyesight!
Further Reading
https://pubmed.ncbi.nlm.nih.gov/17637502/
https://pmc.ncbi.nlm.nih.gov/articles/PMC1772912/
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In this episode, Dr's J and Santhosh once again perform their biweekly roundup of whats new in the medical world, this time with an emphasis on feel good research. Along the way they cover the intersection of Les Mis and the muppets, fat bear week, ozempic effects on imaging studies, xenotransplantation of the first pig liver, gene manipulation, full metal alchemist, innies v outies, the belly button biodiversity project, greek mythology, peripheral immunity and the nobel prize, the 2025 Ignoble award winners, and more! so sit back and relax as we teach you whats new in medical research!
Further Reading
https://www.researchsquare.com/article/rs-7514267/v1
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0329983
https://www.eurekalert.org/news-releases/1100522
https://linkinghub.elsevier.com/retrieve/pii/S0168827825024973
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In this episode Dr's J and Santhosh take on the talk about Tylenol! Along the way they cover some thoughts about the current health and human services secretary, the accidental discovery of a new fever reducer due to a pharmaceutical mix up, methemoglobinemia, brilliant marketing strategies, brand trivia, the Tylenol murders, the dinosaur link, the actual studies on Tylenol and autism, the memory fallacy, and more! So sit back and relax as we pop a couple chill pills to teach the truth about tylenol!
Further Reading
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202400234
https://pmc.ncbi.nlm.nih.gov/articles/PMC8654482/
https://montrealgazette.com/opinion/columnists/the-right-chemistry-the-history-of-tylenol
chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/http://www.nancywest.net/pdfs/McNeilConsumerHealthcareCompany.pdf
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IN this episode Dr's J and Santhosh explore some of the surprising influence and contributions France has made to the medical field. Along the way they cover the French revolution, the beginning of hospital medicine as a specialty, eliminating class barriers in medical practice, the shift away from humoral theory, the creation of health restaurants, the macabre catalyst that drove the new fields of study, empirical medicine and the stethoscope, origins of pathology and research departments, differential diagnosis
Further Reading
https://www.sciencemuseum.org.uk/objects-and-stories/medicine/revolutionary-hospital-medicine
https://pubmed.ncbi.nlm.nih.gov/12964569/
https://www.jstor.org/stable/3655283
https://pdxscholar.library.pdx.edu/cgi/viewcontent.cgi?article=1168&context=younghistorians
https://www.mdpi.com/2409-9252/4/3/18
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In this episode Dr's J and Santhosh continue their halloween hijinks moving on from the undead to the walking dead as they continue to discuss medicine of the spooky! Along the way, they cover the monster mash, historical Haitian zombies studies, tetrodotoxin, the reason zombies need brains, developing undead immunity and the Z nation, our own zombie senescent cells, Tutankhamun's curse and its medical veracity, the real dangers of opening tombs, cancer fighting curses and more! So sit back, relax and join us as we dig up information on grave diseases!
Further Reading
https://www.scientificamerican.com/blog/primate-diaries/a-natural-history-of-vampires/
https://www.jstor.org/stable/3814375
https://pmc.ncbi.nlm.nih.gov/articles/PMC139048/
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In this episode Dr's J and Santhosh open their 12th season with the much looked forward to Halloween special! Along the way, they cover Young Frankenstein, the disease risks of dead bodies, the morticians guide to the recently deceased, vampire tuberculosis and the mercy brown incident, how decomposition can make the dead appear alive, vampire medical weakness to water, possible medical origins of shapeshifting myths, rabies, porphyria and historical blood drinking, medical phlebotomy and vampire cures, the celtic curse
Further Reading
https://www.scientificamerican.com/blog/primate-diaries/a-natural-history-of-vampires/
https://www.jstor.org/stable/3814375
https://pmc.ncbi.nlm.nih.gov/articles/PMC139048/
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In our final episode of season 11, Dr's J and Santhosh once again peruse the pages of proud and perfidious persona as we cover our annual comic book medicine for comicon! ALong the way they discuss the Krakoan age of the Xmen and the mutant pharmacy, drugs that effect longevity, universal antibiotics, vaccine based food, xmen coachella, outside forces effecting drugs, Lazarus anime, time delay medications, Marvels first family, effects of space on gender and memory, medical issues of the fantastic four, and a cosmic comic case study. So sit back and relax as we bring medicine from the page to the real world in this years comic book medicine!
Further Reading
https://www.science.org/doi/10.1126/sciadv.abg6702
https://pmc.ncbi.nlm.nih.gov/articles/PMC11440958/
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In this episode, Dr's J and Santhosh dive into the history and pathology of Entamoeba Histolytica...along the way they cover jurassic poops, artisanal infections, paleoparasitology, medical etymology, protozoan life cycles, amebic evil twins, medical kittens, mitochondria like organisms, trophozoite pathology, diagnosis, symptoms zombie nibble cells, and ipecac and more modern treatment and more! So sit back and relax as we teach you all about the flukes of ameoba!
Further Reading
https://jamanetwork.com/journals/jama/article-abstract/441647
https://sci-hub.ru/https://www.sciencedirect.com/science/article/abs/pii/S1567134816301575
https://journals.asm.org/doi/10.1128/jcm.41.10.4745-4750.2003
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In this episode Dr's J and Santhosh once again perform a roundup of whats new in the medical world, this time with an emphasis on some creative engineered solutions to medical issues. Along the way they cover the plural of hiatus, 3d printing cells inside the body, shape shifting drug treatments, italian respirator innovations, snorkeling ventilators, time dosed vaccine delivery, a brief rant about rfk junior and the vaccine commision, mosquito STD's and more! so sit back, relax and learn whats new in medicine!
Further Reading
https://www.science.org/doi/10.1126/science.adt0293
https://advanced.onlinelibrary.wiley.com/doi/10.1002/adma.202501168
https://www.nature.com/articles/s41598-024-83242-5
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In this episode Dr's J and Santhosh do a body good discussing the history of raw milk and how civilization vastly improved upon it. Along the way, they cover science for spite, Louis Pasteur and his famous revenge beer, nineteenth century infant mortality, Kochs postulates, petty science deathmatch fights, scientist franchise dreams, the definition of pasteurization, Dr Santhosh farmhand upbringing, history of the raw milk moo-vement, bovine tuberculosis, brucellosis, the parsifal study, refutations of raw milk arguments and more! so sit back and relax as this episode, unlike raw milk, does a body good!
Further Reading
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In this classic episode from season 7 Dr’s J and Santhosh cover the cloak and dagger world of espionage medicine. Along the way they cover Cold War Era soviet medicine, Project Artichoke, Dengue fever, brainwashing, truth serums, anticholinergic syndrome, cyanide pills, hydra agents and henchmen preparedness, and a surprising place to keep an escape kit. So sit back and relax as we debrief you on the secrets of the medical spy world!
Sources
1) http://factsanddetails.com/russia/Education_Health_Transportation_Energy/sub9_6b/entry-5145.html
2)truth serum https://www.cia.gov/library/center-for-the-study-of-intelligence/kent-csi/vol5no2/html/v05i2a09p_0001.htm
3) http://www.bioethics.net/2016/03/military-suicide-capsules-and-medical-ethics/
4)https://www.atlasobscura.com/articles/cia-issued-rectal-tool-kit
5)https://www.historyonthenet.com/8-amazing-spy-gadgets-used-during-the-cold-war
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In this classic episode, Dr’s J and Santhosh cover the bacteria actinomyces and its associated diseases. Along the way, they cover infected Egyptian murals, carmen sandiego, lumpy bumpy jaw, anaerobic bacteria, medical etymology, disrespectful bacteria, unique properties of bully bacteria, antibiotic contributions, bacterial colonization, actinomycosis, insidious infections, sulfur granules, diagnosis, treatment and the possible return of just the tip! So sit back and relax as as we dive into a lesser known bacteria and dish the dirt on actinomyces!
Sources
1) https://cmr.asm.org/content/28/2/419
3) https://www.sciencedirect.com/science/article/pii/S0944501318308267
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In this episode, Dr's J and Santhosh dive into the recent spate of religious holidays and news to sift for medical tidbits. Along the way, they cover the history of public health in the church, Pope Francis, the collection of scientific knowledge, variolation, moral objections to vaccination and counterarguments, board certification in the vatican, the pope hospital and personal trainer, passover restrictions on healthcare, kosher medications, healthcare restrictions on shabbat and more! so sit back and relax as we cover holiday healthcare!
Further Reading
https://consumer.crckosher.org/otcmeds/
https://pmc.ncbi.nlm.nih.gov/articles/PMC9121677/
https://epublications.marquette.edu/cgi/viewcontent.cgi?article=3908&context=lnq
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In this episode Dr's J and Santhosh examine the medical conditions and contributions of some famous historical figures. Along the way they discuss Dr J's upcoming nuptials, Dr Santhosh first foray into episode production, Alexander of Macedon, the mysterious circumstances surrounding his death, ancient differential diagnoses, pseudothanatos, guillan barre, timeless treatments, catherine the great and public health initiatives, russian roller coasters, smallpox, escape yachts, vaccination ballets, Peter the Great and bladder dysfunction and more! So sit back and relax as we show you a GREAT time in medicine!
Further Reading
- https://www.ncbi.nlm.nih.gov/books/NBK470418/
- JOHN T. ALEXANDER, Catherine the Great and Public Health, Journal of the History of Medicine and Allied Sciences, Volume XXXVI, Issue 2, April 1981, Pages 185–204, https://doi.org/10.1093/jhmas/XXXVI.2.185
- https://collections.libraries.indiana.edu/iulibraries/s/smallpox-vaccine-exhibit/page/russian-empire
- https://www.passporthealthusa.com/2023/09/catherine-the-greats-advocacy-for-inoculation/
- Griffiths J. Doctor Thomas Dimsdale, and smallpox in Russia. The variolation of the Empress Catherine the Great. Bristol Med Chir J. 1984 Jan;99(369):14-6. PMID: 6367898; PMCID: PMC5077001. https://pmc.ncbi.nlm.nih.gov/articles/PMC5077001/
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