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Two Onc Docs
Sam and Karine
175 episodes
1 day ago
This week’s episode is also due for an update since it aired in 2022. Will be focusing on Hodgkin Lymphoma (HL), both classical and nodular lymphocyte-predominant. We will go into important details on the pathology, staging, Deauville scoring, and treatment for early stage/advanced stage as well as relapsed and refractory HL.
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Medicine
Health & Fitness
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This week’s episode is also due for an update since it aired in 2022. Will be focusing on Hodgkin Lymphoma (HL), both classical and nodular lymphocyte-predominant. We will go into important details on the pathology, staging, Deauville scoring, and treatment for early stage/advanced stage as well as relapsed and refractory HL.
Show more...
Medicine
Health & Fitness
Episodes (20/175)
Two Onc Docs
Hodgkin Lymphoma 2025 UPDATE
This week’s episode is also due for an update since it aired in 2022. Will be focusing on Hodgkin Lymphoma (HL), both classical and nodular lymphocyte-predominant. We will go into important details on the pathology, staging, Deauville scoring, and treatment for early stage/advanced stage as well as relapsed and refractory HL.
Show more...
1 day ago
17 minutes

Two Onc Docs
Anal Cancer 2025 UPDATE
Today’s episode is focusing on what you need to know regarding Anal cancer. This was one of our first episodes back in 2022 so it is time for an updated episode! This will include the important details on risk factors, diagnostic work-up, staging and treatment of both localized and metastatic anal cancer.
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1 week ago
11 minutes

Two Onc Docs
Urothelial ESMO 2025 Updates
This week’s episode will be on many exciting updates were announced at ESMO this October in Berlin from Oct 17-21, 2025, especially in bladder cancer, we continue to make such progress! We discuss key trials in NMIBC (POTOMAC), MIBC (KN-905, IMvigor-011), and metastatic urothelial carcinoma (FORAGER-1, DV + Toripalimab).
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2 weeks ago
13 minutes

Two Onc Docs
Board Review Tidbits
This week’s episode will be focusing on details of the hematology & oncology board exams, how we prepared the days leading up to our exam, and we cover some highly tested topics in both hematology & oncology. We wish the best of luck to everyone taking their boards this year!
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3 weeks ago
16 minutes

Two Onc Docs
Porphyria
This week’s episode will be focusing on Porphyrias…which is very timely since this week is HALLOWEEN and porphyrias are the diseases many people believe started the vampire legend!
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4 weeks ago
9 minutes

Two Onc Docs
Metastatic Breast Cancer 2025 UPDATE
This week’s episode is part 3 of our breast cancer series, with a 2025 update focusing on metastatic breast cancer systemic therapies, toxicities, and supportive care considerations.
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1 month ago
11 minutes

Two Onc Docs
Localized Breast Cancer 2025 UPDATE
This week’s episode will be focusing on treatment options for localized breast cancer with 2025 updates. We will go over important details on indications for adjuvant radiation, as well as therapies based on the ER/PR/HER-2 receptor status.
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1 month ago
17 minutes

Two Onc Docs
Breast Cancer Screening, Prevention & Intro 2025 UPDATE
October marks Breast Cancer Awareness Month. We are providing 2025 update for our 3 part breast cancer episodes, in part 1 today we cover an introduction on breast cancer screening, prevention.
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1 month ago
17 minutes

Two Onc Docs
Esophageal and Gastrosophageal Junction (GEJ) Cancer 2025 UPDATE
This week’s episode will be focusing on Esophageal and Gastrosophageal Junction (GEJ) Cancer. We will go over important details on the risk factors, diagnosis, and treatment for both localized and metastatic esophageal cancer.
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1 month ago
14 minutes

Two Onc Docs
Immune Thrombocytopenia Purpura ( ITP) 2025 UPDATE
This week’s episode will be focusing on Immune Thrombocytopenia Purpura ( ITP). We will go all the important details on causes, mechanism, diagnosis and treatment. The last time we covered this topic was in Sept 2022, and this comes up ALL the time in heme consults, and there will definitely be board review questions. It may also be tested on IM boards.
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2 months ago
9 minutes

Two Onc Docs
Bone Sarcomas 2025 UPDATE
This week’s episode will be an update on Bone Sarcomas. We will go over the important details on diagnosis, staging, subtypes and treatment of a few bone sarcomas. Just like Soft Tissue Sarcomas, these are RARE tumors encompassing 1% of all adult cancers and having multiple subtypes. They are more common in children, and most of our bone sarcoma recommendations that are testable are based on pediatric data.
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2 months ago
13 minutes

Two Onc Docs
Soft Tissue Sarcomas 2025 UPDATE
This week’s episode will be focusing on soft tissue sarcomas. We last recorded this topic in 2023, and well we have some new FDA approvals and updates since then. We will go over the important details on the diagnosis, subtypes and treatment of a few soft tissue sarcomas. These are RARE tumors encompassing 1% of all adult cancers and having multiple subtypes that range from noncancerous tumors such as desmoid tumors to aggressive cancers and everything in between.
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2 months ago
21 minutes

Two Onc Docs
Thrombotic Thrombocytopenic Purpura (TTP) and other TMAs 2025 UPDATE
Today’s episode will focus on an update for commonly tested Thrombotic microangiopathies (TMA) such as Thrombotic Thrombocytopenic Purpura (TTP). This will include the high yield facts on mechanism, presentation, diagnostic work-up, and treatment of TTP, and also discuss Hemolytic Uremic Syndrome (HUS), and atypical HUS.
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3 months ago
10 minutes

Two Onc Docs
Gastric Cancer 2025 UPDATE
This week’s episode will be focusing on Gastric Adenocarcinoma. We will go over all the important details on risk factors, diagnostic work-up, staging and treatment for both local regional disease and metastatic disease with updates in 2025 since we last covered this topic in 2023.
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3 months ago
18 minutes

Two Onc Docs
Endometrial (Uterine) Cancer 2025 UPDATE
We are updating another important GYN ONC topic: endometrial (uterine) cancer. We will go over all the important details on the risk factors, presentation, diagnosis, staging & treatment options. We will also cover rare uterine malignancies at the end of the episode.
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3 months ago
12 minutes

Two Onc Docs
Metastatic Kidney Cancer x Uromigos 2025 UPDATES (Part 2)
Today’s episode we will cover 2025 updates for metastatic renal cell carcinoma. We will discuss risk categories, treatment options, and variant histologies. We are so excited to have Dr. Tom Powles and Dr. Brian Rini from the urologic oncology podcast Uromigos sharing their expertise on today's episode as well!
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3 months ago
30 minutes

Two Onc Docs
Localized Kidney Cancer x Uromigos 2025 UPDATES (Part 1)
Today’s episode we will cover 2025 updates for localized renal cell carcinoma (RCC) with Dr. Tom Powles and Dr. Brian Rini from the urologic oncology podcast Uromigos! We will discuss risk factors, the presentation, staging, and treatment options.
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4 months ago
20 minutes

Two Onc Docs
Cervical Cancer 2025 UPDATE
This week’s episode will be focusing on Cervical Cancer with some updates since we last released this topic in 2022. We will go over important details on prevention, risk factors, diagnosis & treatment.
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4 months ago
11 minutes

Two Onc Docs
Oncologic Emergencies 2025 Update
This week’s episode is an update on a must-know topics both for new fellows & residents. We will go over clinically important oncologic emergencies including brain metastases, hypercalcemia of malignancy, cord compression and SVC syndrome.
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4 months ago
12 minutes

Two Onc Docs
ASCO 2025 Plenary - MATTERHORN
This week’s episode will be focusing on one of the GI plenary session abstracts presented at the ASCO Annual Meeting 2025, the MATTERHORN trial: phase 3 durvalumab + FLOT which is 5FU leucovorin, oxaliplatin and docetaxel in resectable gastric or GE junction CA.
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4 months ago
12 minutes

Two Onc Docs
This week’s episode is also due for an update since it aired in 2022. Will be focusing on Hodgkin Lymphoma (HL), both classical and nodular lymphocyte-predominant. We will go into important details on the pathology, staging, Deauville scoring, and treatment for early stage/advanced stage as well as relapsed and refractory HL.