Study Title: Combined analysis of a serum mRNA/miRNA marker signature and CA 19-9 for timely and accurate diagnosis of recurrence after resection of pancreatic ductal adenocarcinoma: A prospective multicenter cohort study Link: https://onlinelibrary.wiley.com/doi/10.1002/ueg2.12676 Guest: Professor Malte Buchholz

1. Featuring: KPIs in EGD, Rifaximin-α for HE, Updated Dysphagia Guidelines, AI in Endoscopy, and MSK Injuries in Endoscopists DOI: https://doi.org/10.1002/ueg2.70001 2.Rifaximin-α in Patients With Recurrent Episodes of Hepatic Encephalopathy Due to Cirrhosis Reduces Healthcare Utilization DOI: https://doi.org/10.1002/ueg2.12767 3. Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility DOI: https://doi.org/10.1002/ueg2.70062 4. Challenges in Implementing Endoscopic Artificial Intelligence: The Impact of Real-World Imaging Conditions on Barrett's Neoplasia Detection DOI: https://doi.org/10.1002/ueg2.12760 5. Endoscopy-Related Musculoskeletal Injuries: A Systematic Review and Meta-Analysis on Prevalence, Risk Factors and Prevention DOI: https://doi.org/10.1002/ueg2.70042

1. Concomitant Use of Etrasimod With Opioids or Antidepressants in Patients With Ulcerative Colitis—A Safety Analysis https://onlinelibrary.wiley.com/doi/10.1002/ueg2.12745 https://doi.org/10.1002/ueg2.12745 2.Multiple Concomitant Precipitating Factors of Hepatic Encephalopathy Are Associated With a Poor Prognosis in Patients With Cirrhosis Admitted to Intensive Care Unit https://onlinelibrary.wiley.com/doi/10.1002/ueg2.12706 https://doi.org/10.1002/ueg2.12706 3. Duodenal Laser Ablation for Treatment of Type 2 Diabetes: Results of First in Human Study https://onlinelibrary.wiley.com/doi/10.1002/ueg2.12762 https://doi.org/10.1002/ueg2.12762 4. Chronic Kidney Disease Increases Risk of Delayed Post-Polypectomy Bleeding: A Large-Scale Propensity Score-Matched Analysis https://onlinelibrary.wiley.com/doi/10.1002/ueg2.70013 https://doi.org/10.1002/ueg2.70013

GI pearls from the latest literature published in UEGJ

Ahsen Ustaoglu interviews Dr Celia Escudero-Hernandez on their transcriptomic study delving into the pathogenesis of lymphocytic colitis, where they identified two subtypes of lymphocytic colitis: channelopathic and inflammatory lymphocytic colitis, which could pave the way for novel biomarkers and therapeutic avenues. 

In this episode, Ahsen Ustaoglu interviews Prof Vincent Wong on their comprehensive review of non-invasive biomarkers and imaging tools for non-alcoholic fatty liver disease which has a rapidly rising incidence worldwide. 

Ahsen Ustaoglu interviews Dr Mathias Brugel on their targeted screening analysis of pancreatic adenocarcinoma risk with organoclorine pesticides from the PESTIPAC study

In this episode, Dr. Tarik Kani  interviews Dr Christian Agboton from USA about the optimal position of Vedolizumab in long-term Crohn's Disease

Join Ahsen Ustaoglu and H. Tarik Kani as they interview Dr Asa Frandemark on their study investigating work impairment in disorders of gut-brain interactions which assessed retrospective data from the Rome Foundation Global Epidemiology Study 

In this episode, Dr. Tarik Kani  interviews Dr Milou van Riswijk from The Netherlands about a new bowel cleansing system which was designed to overcome an important issue for endoscopists and patients.

In this episode, Ahsen Ustaoglu interviews Dr Raul Velamazan to discuss their findings from the multicentre RELAPSTONE study on recurrence patterns and risk factors for relapse after first admission of patients with symptomatic gallstone disease

Dr. Tarik Kani  interviews Dr Alberto Zanetto from Italy, on their study which they were created a new model to predict acute-on-chronic liver failure in decompensated cirrhosis.

Dr Ahsen Ustaoglu interviews Dr Rajan Singh and Dr Hannah Zogg from the University of Nevada, USA, on their study which investigated the role of microRNA 10b-5p in regulating gut barrier function in an in vivo model of diabetes and gastrointestinal dysmotility, important mechanistic work in the field of Neurogastroenterology.

In this December special episode, your UEG Journal podcast hosts H. Tarik Kani and Ahsen Ustaoglu are joined by UEG Talks podcast hosts Egle Dieninyte and Pradeep Mundre in hosting very special guests at UEG Week 2023 in Copenhagen. You can expect to hear important insights from Dr Enrique de Madaria and UEG Journal Editor-in-Chief Prof Joost Drenth, as well as Young GIs.

Dr. H. Tarik Kani talks to Dr. Anouk Wijnands (Netherlands) about her multicenter cohort study that investigated the relationship between smoking and colorectal neoplasia in patients with Inflammatory Bowel Disease with a 10-year follow-up.

Dr Ahsen Ustaoglu interviews Dr Iris Levink on her study investigating the additive value of CA19.9 monitoring in a pancreatic cyst surveillance program, part of the PACYFIC-trial (www.pacyfic.net).

Dr. H. Tarik Kani talks to Dr. Axel Dignass (Germany) about his recent publication about the impact of Ustekinumab on health-related quality of life in moderate-to-severe Crohn’s disease which was an open-label, multicenter, randomized study evaluated the quality of life prospectively in Crohn’s patients who treated with Ustekinumab.