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Timestamps:00:00 Intro00:44 My results in 202506:19 Body composition goals16:00 Bon Charge sponsorship16:52 My 2025 fitness results25:05 My 2026 fitness goals30:25 My workout plan for 202635:05 My nutrition plan for 202643:27 My supplement protocol for 202646:37 My sleep routine and goals48:47 My bloodwork results for 2025 and goals for 202601:01:07 Auxiliary routines01:05:05 ConclusionGet to top 1% health: https://youtu.be/8M9uHhFf26c

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Start rewinding your biological clock: https://www.siimland.co/course

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Timestamps:

00:00 Intro

00:15 100 supplements ranked from worst to best

57:00 Bon Charge sponsorship

57:55 How to eliminate microplastics and heavy metals from your body feat Dr Anil Bajnath

01:27:20 Nutrition masterclass with Physionic and Dr Greg Potter

02:27:25 Exercise masterclass with Physionic and Dr Greg Potter

03:17:15 Best performing video of the year

03:29:30 Top underrated video of the year

03:36:14 Sleep and circadian clock dysfunction feat Dr Greg Potter

04:04:38 Skin anti-aging masterclass with Dr Alexis Ortega

Get to top 1% health: https://youtu.be/8M9uHhFf26c

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/

Timestamps:

00:00 Intro

00:15 Zone 2 cardio

01:44 Napping

03:03 Walking

05:09 Polyphasic sleeping

06:47 Mouth breathing

07:52 Soleus pushups

09:40 Stretching

11:10 Mobility

12:03 Yoga

13:20 HIIT

14:20 Sprinting

14:48 Plyometrics

16:12 Morning sunlight

17:05 Evening sunset

17:52 Blocking out blue light

19:12 Red light therapy

20:37 Infrared light

21:43 Supplements

23:30 Education

25:20 Problem solving

26:14 Weight lifting

26:56 Bilingualism

27:10 Sunbathing

28:54 Tanning beds

30:06 Coffee and teas

31:28 Low carb diet

33:26 Low fat high carb diet

34:04 Vegan diet

34:36 Vegetarian diet

35:00 Carnivore diet

37:07 Paleo diet

37:45 Calisthenics

39:15 Mediterranean diet

40:20 Sugar diet

40:58 Hydration

41:42 Smoking

42:00 Alcohol

43:40 Vaping

44:00 Mouth tobacco

44:35 Hyperbaric oxygen therapy (HBOT)

45:40 Sauna

47:09 Total plasma exchange

47:53 Meditation

48:49 Religion

50:10 Purpose

51:30 Mindfulness

52:14 Intermittent fasting

53:15 Low calorie diet

55:40 If it fits your macros diet

57:30 Pet ownership

58:57 Marriage

01:00:57 Ice bath

01:01:57 Having children

01:03:29 Social health

01:04:23 Having fun and play

01:04:40 Mental health

01:05:03 Extended fasting

01:07:07 Forest bathing

01:08:02 Fasting mimicking diet

01:09:10 Juice fasting

01:09:41 Dry fasting

01:11:16 Protein restriction

01:12:17 Hot baths

01:13:40 Time-restricted eating

01:14:10 Circadian mismatch

01:14:50 Sleep consistency

01:15:23 Chronic stress

01:16:00 Junk food

01:16:25 Water filtration

01:16:50 Air filtration

01:17:00 Outdoor pollution

01:17:20 Sitting lifestyle

01:17:43 Sleep 7-8 hours

01:18:09 Regular bloodtests

01:18:40 Continuous glucose monitoring

01:19:19 Exercise snacks

01:19:57 Standing workdesk

01:20:53 Nasal breathing

01:21:03 Breathing exercises

01:21:38 Recreational drugs and weed

01:22:26 Peptides

01:23:30 HRT & TRT

01:27:04 Sleep 4-6 hours

01:27:28 Stem cell therapy

01:28:17 Team sports

01:28:40 Steroid cycle

01:29:10 Grounding

01:29:32 Mouth taping

01:29:51 Artificial sweeteners

01:31:30 Hypochondria

01:33:50 Overview

My 2025 supplement list guide: https://www.siimland.co/supplement-list-2025

100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Get to top 1% health: https://youtu.be/8M9uHhFf26c

Start rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:00:00 What level of sports performance is unhealthy04:15 How much protein is bad for aging and longevity11:45 Bon Charge sponsorship12:45 Do I want to reach the longevity escape velocity16:40 Absorbing supplements through the skin18:40 Optimal level of testosterone for longevity22:50 Should you cycle supplements on and off27:26 How I managed to follow a healthy lifestyle in my 20s31:07 How much red light therapy can you do per day33:10 Role of stress in longevity39:35 What to do against smog and air pollution43:50 Training fast twitch muscle fibers instead of lifting weights48:30 My all out supplement stack

100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Jon Berner, MD PhD is a board certified Psychiatrist from Seattle with 27 years of experience. He's also published several scientific papers.

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:00:00 Intro00:20 Why Dr Berner became interested in lithium04:50 Lithium’s benefits in Alzheimer’s and dementia10:50 Lithium’s effects on mTOR and autophagy12:50 Bon Charge sponsorship13:40 Clinical evidence for lithium in dementia18:20 What’s the optimal dose for lithium26:25 Lithium for bipolar and hyperactive brains29:25 Lithium as potential treatment in neurodegeneration31:55 Lithium’s effects on kidneys34:20 Personal experience with taking lithium40:40 Is it safe to take lithium prophalactically over the counter47:55 Rapamycin synergy with lithium51:45 AI and human development

Dr Berner's practice: https://www.woodinvillepsychiatric.com/

100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Yip (Zico) Tszho is the Chief Executive of Lonvi Biosciences, a longevity-drug start-up, in Shenzhen, China. They're developing pharmaceuticals for extending human lifespan. We discuss their first senolytic called PCC1.

Timestamps:00:00 Intro00:15 Articles about a pill making people live to 15002:50 What is PCC1 and how is it made07:10 How much can targeting senescence extend lifespan12:25 Bon Charge sponsorship13:15 Dose of PCC1 for senolytic and senomorphic effects18:30 PCC1 extending lifespan in mice by 9.4%23:20 Absorption rate of PCC1 and other senolytics27:10 Senolytics for young vs old age31:10 Human study on PCC134:40 What’s the optimal dose for senolytics38:05 Biomarkers of cell senescence40:10 Senolytic benefits on skin and retina46:35 What’s going on in Chinese longevity science52:10 Future direction of PCC1PCC1 studies: https://lonvibio.com/pages/science

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Brady Holmer is a science writer and researcher with a Master's degree in Human Performance from the University of Florida

Timestamps:00:00 Intro00:40 Why heat acclimation has performance benefits08:10 How to train heat acclimation12:40 Bon Charge sponsorship13:30 Benefits of the sauna for fitness18:25 Saunas and injury recovery22:30 Cold exposure and exercise performance26:45 Cooling down during and before exercise31:40 How often to train heat acclimation and sauna37:05 Sauna and HRV38:10 How long to stay in the sauna41:15 Electrolytes and dehydration acclimation46:25 Differences between men and women in heat acclimation47:00 Does heat acclimation have longevity benefits49:05 Does cold exposure have longevity benefits54:30 Which research should be done more on heat acclimation

First podcast with Brady about VO2 max: https://youtu.be/xLDaFhN6h8I

Brady Holmer Twitter: https://x.com/B_Holmer

Brady Holmer website: https://www.bradyholmer.com/Start rewinding your biological clock: https://www.siimland.co/course

Join our upcoming retreat in January 2026: https://www.siimland.co/retreat

Timestamps:Introduction (00:00)Discussion on longevity clinics and testing (01:52)Essential health tests and biomarkers (05:45)Improving VO2 Max and cardiovascular health (11:28)Blood tests and metabolic health (16:42)Hormone tests and longevity (21:35)Microbiome tests and toxicity (26:55)Microplastics and environmental toxicity (32:14)Food sensitivity testing (39:01)NAD testing and energy metabolism (41:50)Comprehensive health retreat (49:29)

Dr. Joy Kong Youtube channel: https://www.siimland.co/retreat

Dr. Mark Tarnopolsky is a Professor and Division Head of Neuromuscular and Neurometabolic Disorders in the Department of Pediatrics at McMaster University. He completed a PhD in Cell Biology and Metabolism in 2001.

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Timestamps:00:00 Intro00:25 What are mitochondria03:55 Mitochondria in aging and longevity06:00 Oxidative stress, inflammation, and longevity09:30 Antioxidants and benefits of exercise12:40 Bon Charge sponsorship13:30 Who should take antioxidants21:30 Mark’s antioxidant cocktail study24:30 Why is exercise the best thing for your mitochondria30:35 How endurance training shapes the mitochondria35:10 High intensity interval training36:50 Role of mitochondria in muscle loss42:00 Nutrition for mitochondrial health46:50 Supplements for mitochondrial health53:35 Stimulating mitophagy

Dr Mark Tarnopolsky research page: https://scholar.google.com/citations?user=4jhi_KkAAAAJ&hl=en

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:00:00 Intro00:48 The genetics of a 117-year-old woman08:16 Resilience, immunity and longevity14:33 Muscle building genetics19:33 FOXO3 and stress resilience24:53 FOXO3 gene editing32:08 Can telomere lengthening be harmful to some individuals38:58 IGF-1 and growth hormone and longevity50:08 Genetically short sleepers54:38 What you should know about your longevity genes

First podcast with Tyler about genetics and supplements: https://youtu.be/9GLbTEYewUs

Tyler Panzner channel: https://www.youtube.com/@drtylerpanzner

Timestamps

0:00 – Introduction

4:12 – Humans adapt, and that changes the rules

9:58 – Diet diversity, sensitivities, and n of 1

16:51 – Assess first: biomarkers that predict disease risk

18:27 – Fixing sleep, movement, diet, environment

22:47 – Caution on rapamycin, metformin, methylene blue

25:54 – FOXO3 stem-cell study and what it means

37:15 – Mindset and willpower as real enhancers

41:44 – TMG, astaxanthin, melatonin, creatine

47:09 – VO2 max priorities and performance trade-offs

48:51 – Balancing fitness with joy and purpose

53:18 – Biomarkers mediate risk more than labels

1:01:00 – 2030–2040: what is realistic

1:04:02 – Immortality probabilities and living well now

Julian Issa video podcast: https://youtu.be/vV8yMVGLG6Y?si=XiLxOx0bSSM-xT-v

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:

00:00 Does exercise increase inflammation

03:03 Melatonin megadosing research

04:23 NOVOS vs Blueprint VS DoNotAge

07:44 Hidden things that contribute to my health

12:14 Bon Charge sponsorship

13:05 How to improve night shift work

15:40 Supplements to take before the sauna

17:15 Does caffeine age the brain

19:34 Can you make up for lost sleep

20:40 Thoughts on Urolithin A

23:14 Doing too much for longevity

27:59 How to stop waking up at 3AM

30:57 How much sodium do I consume

33:20 Do sleep supplements blunt natural sleep

37:07 Inflammation in longevity

41:23 Importance of good relationship with food

Get my 2025 supplement guide: https://www.siimland.co/supplement-list-2025

Timestamps:00:00 Intro00:14 Taurine01:19 Apigenin01:55 Resveratrol03:20 Rapamycin04:55 Metformin06:11 Calcium AKG07:30 Melatonin08:16 SIRT609:05 NAC09:43 NMN, NR, Niacinamide11:10 Niacin13:58 Glycine15:16 Spermidine16:44 Omega-3s17:40 Creatine18:48 Pterostilbene19:19 Magnesium20:16 Vitamin K220:45 Sulforaphane21:34 Curcumin22:08 Methylated B vitamins22:33 Glutathione24:08 Lithium24:55 Lutein & Zeaxanthin25:30 Vitamin C26:29 Ergothioneine27:23 Methylene blue28:46 Multivitamin29:37 Aged garlic extract30:22 Astaxanthin31:06 TMG31:50 Ginger32:15 CoQ1032:53 PQQ33:24 Chondroitin33:45 MSM32:25 Glucosamine34:54 Conclusion

100 supplements ranked worst to best: https://youtu.be/W8DZbYyuDmA

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/

Chris Dancy is called 'the most connected man on Earth' because of his pioneering use of technology in everyday life and health optimization.

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Timestamps:00:00 Intro00:23 Why Chris is the most connected man on earth03:38 How Chris used technology to lose weight and get healthy08:43 How technology changes the human experience in the future10:43 Best tools 16:28 The technology Renaissance period20:43 Bon Charge sponsorship21:38 Implants24:18 Hacking time33:28 Meditation and mindfulness36:48 Does time go by faster if you’re stuck in daily routines47:38 How Chris’ perception of time has changed as he got older52:43 Will virtual reality extend perception of lifespan59:03 How to make technology better for your health

Chris Dancy website: https://www.chrisdancy.com/

Josh Witteldorf is a PhD in physics who pivoted to researching aging and investigated the evolutionary reasons for aging and human lifespan. He's written the book Cracking the Aging Code.

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Timestamps:00:00 Intro00:30 How Josh, as a physicist, got into aging research04:35 Why aging is an evolutionary program13:50 Why humans die and age20:45 Bon Charge sponsorship21:35 Why did aging evolve as an adaptation24:40 Species that are biologically immortal30:25 Shocking way group selection selects for aging and death33:55 How predator-prey relations select for aging43:15 Can humans control our own evolution48:15 A long-term human calorie restriction experiment in Biosphere 252:50 Insulin’s effects on aging 55:20 mTOR and aging57:15 Can you deprogram aging and extend lifespan01:10:00 Gene editing01:15:15 Josh’s predictions for the future

Josh Mitteldorf blog: https://scienceblog.com/joshmitteldorf/

Josh's book Cracking the Aging Code: https://amzn.to/4mFmC6m

Start rewinding your biological clock: https://www.siimland.co/course

Get my free bloodwork cheat sheet: https://www.siimland.co/bloodwork-cheat-sheet

Timestamps:00:00 Intro00:32 Resting heart rate02:27 hsCRP03:32 VLDL03:52 LDL particle count04:31 Homocysteine 05:26 Respiratory rate06:30 VO2 max07:36 Body fat percentage09:18 BMI11:57 HRV14:14 Waist circumference and waist to hip ratio16:00 Visceral fat mass and liver fat18:42 White blood cells20:35 Albumin21:11 Muscle mass22:40 Grip strength24:15 Appendicular lean mass index25:31 Creatinine27:55 eGFR29:20 Cystatin C29:32 Biological age tests31:45 Speed of aging test32:45 Phenoage34:25 Bone density36:00 Lung force36:59 Lp(a)38:15 Oxidized LDL39:00 Testosterone43:40 SHBG45:22 Estradiol (E2)46:42 Resting metabolic rate49:00 Body temperature51:48 Liver enzymes (ALT, AST, GGT, ALP)53:14 ApoB55:10 IGF-157:30 ApoA59:30 Calcium score in the arteries (CAC)01:00:46 Carotid intima media thickness (CIMT)01:03:18 Iodine01:05:09 Thyroid hormones (T3 and T4)01:08:00 Progesterone and pregnenolone01:08:51 Thyroid-stimulating hormone (TSH)01:09:47 BNP (cardiac stress)01:10:22 Hemoglobin01:11:22 Iron and ferritin01:12:56 Uric acid01:13:49 HDL cholesterol01:14:53 HbA1c01:15:39 Fasting insulin01:15:58 Fasting glucose01:17:23 Fructosamine01:18:11 Triglycerides01:19:07 Omega-3 index01:20:26 Omega-6-to-3 ratio01:21:01 Red cell distribution width (RDW)01:21:22 Platelets01:22:22 Mean corpuscular volume (MCV)01:22:39 LDL cholesterol01:23:18 Mean corpuscular hemoglobin (MCH)01:23:33 Blood urea nitrogen (BUN)01:23:57 DHEA-S01:24:52 Vitamin D01:26:07 HOMA-IR01:26:26 Red blood cells01:26:38 Hematocrit01:27:01 Erythrocyte sedimentation rate (ESR)01:27:38 LP-PLA201:28:15 Electrolytes01:29:09 Total cholesterol01:29:23 B vitamins01:30:29 Total iron binding capacity (TIBC) and transferrin saturation01:31:00 Heavy metals01:32:48 Microplastics01:34:54 Cortisol01:36:10 TNF-alpha01:36:50 How much can you lift?01:39:22 Cooper test01:40:25 Microbiome diversity01:42:08 Conclusion

100 supplements ranked worst to best: https://youtu.be/W8DZbYyuDmA

Greg Potter, PhD, is a circadian rhythm and time-restricted eating expert who researches sleep, circadian rhythms, and time-restricted eating

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Timestamps:00:00 Intro01:05 Circadian clock dysfunction and hallmarks of aging10:35 How the circadian clocks affect aging and lifespan17:00 Bon Charge sponsorship17:55 Why clock dysfunction contributes to aging24:50 What causes circadian clock dysfunction30:00 NAD metabolism and clock function31:30 Calorie restriction and meal timing36:00 Night owls vs morning larks39:35 Shift work42:18 Melatonin supplementation46:00 Clock enhancing nutraceuticals49:10 Should you supplement melatonin at old age59:45 Morning cortisol circadian rhythm01:04:50 Sunlight and UV & infrared light exposure01:09:05 How to keep your circadian clock system working well during aging

Greg Potter YouTube channel: https://www.youtube.com/@gregpotterphd

Greg Potter PhD Instagram: https://www.instagram.com/gregpotterphd/

Exercise roundtable with Greg and Nic: https://youtu.be/8eW5gNiSxUU

Longevity supplement roundtable with Greg and Nic: https://youtu.be/OBPacg_tVuQ

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:

00:00 Intro00:22 Dr Robbins background in longevity research01:57 What is cell senescence07:52 Benefits of senescent cells early in life09:07 Does eliminating senescent cells increase lifespan14:50 How to eliminate senescent cells17:35 Most researched senolytics22:15 Can you reverse the age of senescent cells24:00 Immune system and aging26:20 Rapamycin29:20 Practical tips to reduce your senescent cell burden33:50 Are GLP-1 receptor agonists anti-aging drugs36:55 Should people take senolytics41:05 Gene therapies for senescent cells50:45 What things need to be focused on for breakthroughs in longevity research

Dr. Robbins is a Professor of Biochemistry, Molecular Biology and Biophysics and Associate Director of the Masonic Institute on the Biology of Aging and Metabolism (MIBAM) and the Medical Discovery Team on the Biology of Aging at the University of Minnesota. Paul Robbins Research lab: https://robbins.umn.edu/

Full routine to go from average to top 1% health: https://youtu.be/dHfhTQSBAfg

➡ Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Start rewinding your biological clock: https://www.siimland.co/course

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Timestamps:00:00 Intro00:20 Greg and Siim's background06:35 Our opinion on what’s the best diet12:50 What is most important: how much you eat, what you eat, when you eat18:15 Bon Charge sponsorship19:05 How important is the timing of when you eat42:30 Best diet for top 1% longevity, top 1% athletics and general wellbeing53:00 How to structure your calories, protein, carbs and fats01:07:15 Better and worse forms of protein, carbs and fats01:30:20 Low protein vs high protein for longevity02:09:25 Low carb vs plant-based diet02:10:00 Diet tribalism on social media02:33:00 Final words

Exercise roundtable with Greg and Nic: https://youtu.be/8eW5gNiSxUU

Longevity supplement roundtable with Greg and Nic: https://youtu.be/OBPacg_tVuQ

Greg Potter YouTube channel: https://www.youtube.com/@gregpotterphd

Greg Potter PhD Instagram: https://www.instagram.com/gregpotterphd/

Physionic Instagram: https://www.instagram.com/physionic_phd/

Physionic YouTube channel: https://www.youtube.com/@PhysionicStart rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Get your free personalized health review: https://www.siimland.co/review

Timestamps:00:00 Intro01:10 Summary of our biomarker differences02:30 Fitness markers09:45 Body composition markers14:45 Inflammation and immune markers19:30 Metabolic health markers24:15 Cardiovascular markers36:30 Kidney markers43:45 Liver markers47:00 Hormone markers53:20 Experimental longevity tests56:45 PhenoAge biological age test01:01:40 RecapMy Evidence-Based Longevity Routine: https://youtu.be/4xkRcfeGDooStart rewinding your biological clock: https://www.siimland.co/course